The Lab Report

Today we meet Dr. Casey Means - a head & neck surgeon who made a big leap from traditional to functional medicine. She specializes in metabolic health with a focus on the whole-food, plant-based approach to diet. Dr. Means is also co-founder and Chief Medical Officer for a company called Levels . Levels produces digital health products, such as continuous glucose monitors, to inspire healthy behavior change.

In this episode, you’ll hear part 1 of an extensive interview discussing a variety of topics. Listen as we delve into Dr. Means’ path to functional medicine and her thoughts on plant-based diets. 

Today on The Lab Report:

• 3:10 Introducing Dr. Casey Means and her path to functional medicine
• 11:10 Nutrigenomics and the plant-based diet
• 15:00 Curcumin and sulforaphane
• 16:25 What about meat?
• 19:00 Biochemistry and metabolizing fatty acids
• 21:20 What about other diets (keto, carnivore, etc.)?

Additional Resources:

Dr. Means' Website

Levels

NutrEval

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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Did you know that there is a connection between the brain and the GI tract? This gut-brain axis communicates information in both directions. The commensal bacteria in our gut and their metabolites can directly affect our memory and mood, while our brain can alter bacterial patterns and GI function.

Today we discuss some of the mechanisms by which this axis sends and receives those signals. We also talk about the importance of addressing both when optimizing health.

Today on The Lab Report:

• 2:30 New Game Alert!  Vegetablization of names
• 4:05 Question of the Day/Fireball:

Since the gut-brain axis is bidirectional, where do you start when it comes to treatment?

• 6:45 What is the gut-brain axis?
• 8:10 Communication mechanisms from the GI tract to the brain
• 13:20 How the brain affects the gut
• 16:50 Where do you start when it comes to treatment?
• 18:20 Psychobiotics
• 20:10 Testing

Additional Resources:

GI Effects Comprehensive Stool Profile

Adrenocortex Stress Profile

 Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

In functional medicine, we often focus on the GI tract to uncover and treat the root causes of many chronic diseases. But many clinicians just don’t know where to start. The “5R Protocol” is a helpful tool to guide treatment decision-making. The “5 R’s” are Remove, Replace, Re-inoculate, Repair, and Rebalance. What exactly does this mean? How do you translate this to clinical practice?

 In this episode, we discuss the meaning of each “R”. We also explain how to apply these to a patient’s clinical presentation and stool test results.

Today on The Lab Report:

• 2:15 Introducing the “5R Protocol”
• 4:30 Remove - remove what? How?
• 13:30 Replace – supporting underlying GI function
• 21:40 Re-inoculate – pre- and probiotics
• 25:00 Repair – intestinal permeability and inflammation
• 27:45 Rebalance – lifestyle modification and the GI tract
• 30:10 Did we just add a sixth R?  Yep!
• 30:50 Question of the Day: How long do you wait to retest?

Additional Resources:

GI Effects Comprehensive Stool Profile

 Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Drew Manning is a health and fitness expert who became a world-wide sensation with his Fit2Fat2Fit experiment years ago. He gained and lost 75 pounds on purpose to understand the psychology behind weight loss. This transformed the way the fitness industry approached helping clients. He recently announced he’s doing it again this year as he turns 40 (Fit2Fat2Forty) to bring awareness to the mental-emotional part of body transformation.

In this episode, Drew discusses his latest journey and his new approach. Hear about the incredible amount of education he’s hoping to bring to this experiment and how you can follow along and learn. Additionally, because Drew is a leading voice in the ketogenic diet industry, we engage him in a rapid-fire “Keto FAQ” segment.

“Empathy is one of those things that can be so transformative and a huge catalyst for change.” – Drew Manning

Today on The Lab Report:

• 3:25 Meet Drew Manning and hear about why he’s undertaking “Fit2Fat2Forty”
• 7:15 What he learned from his first journey and how it changed his current approach
• 11:25 The psychology of gaining and losing weight
• 16:00 Mind-body practices for emotional eating
• 17:45 Gaining the weight - challenging popular diets
• 22:10 Rapid-fire Keto FAQ’s with Drew
• 29:00 The Fireball

Additional Resources:

fit2fat2fit

fit2fat2forty

Drew's Podcast

fit2fat2fit Facebook

@fit2fat2fit Instagram

Complete Keto Guide

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Proteins are large molecules made up of smaller building blocks called amino acids. As a macronutrient, protein can be obtained in our diet from both plants and animals. Protein is metabolically critical and structurally necessary to keep us healthy. When protein is broken down into amino acids, each of them have their own function and importance as well. Are you getting enough protein in your diet? What happens in the body if you’re deficient? How do you get more?

In today’s episode, we discuss all things protein. We also single out a few specific amino acids and touch on what makes them important.

Today on The Lab Report:

• 2:45 Introducing protein and amino acids
• 4:35 What’s the difference between a peptide and a protein?
• 6:00 How much protein do we need every day and where do we get it?
• 11:35 Protein digestibility and other important dietary factors
• 13:10 Amino acids – essential and nonessential
• 16:00 ‘Off the Cuff’ with the Medical Affairs Team: What’s your favorite amino acid?
• 31:35 How do we test amino acid levels?
• 33:00 Question of the Day: What are some patterns of amino acids and what do they mean?

Additional Resources:

Amino Acid Analysis

Metabolomix +

NutrEval

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Multi-omics is the layering of genetic information (genomics) with laboratory biomarker results (metabolomics) to understand the root cause of disease and risk. This educational series focuses on genetic variants in specific enzymes and explains how to evaluate the systemic effects.

Today’s episode revolves around the enzyme cystathionine-beta-synthase (CBS). This enzyme is important for homocysteine metabolism, sitting at a branch point between two important cycles: methylation and transsulfuration. The action of this enzyme is important for balancing the critical functions of methylation with the creation of glutathione and energy. Listen to understand why this enzyme is important and what a genetic variant in CBS might mean for your patients.

“You’ve got to zoom out. You’ve got to look at all of the factors which regulate the CBS enzyme.” – Michael Chapman, ND

Today on The Lab Report:

• 2:20 Reminder of what we mean by multi-omics
• 4:50 Introducing the CBS enzyme and the sink drain metaphor
• 7:40 The genetics of CBS – the silent mutation – and its potential effects
• 12:40 Better Know A Biomarker:  Cystathionine!
• 16:20 Activators and inhibitors of CBS and its effects on other biomarkers
• 18:55 Question of the Day:  Does a CBS SNP cause elevated ammonia levels?
• 21:40 Evaluating surrounding biomarkers and how do you treat this SNP?

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Most of us in functional medicine understand the importance of nutrition in addressing chronic disease. Dr. Kasia Kines holds a doctorate degree in Clinical Nutrition and has helped thousands of patients get to the root cause of their illnesses. Dr. Kines also happens to be a key opinion leader on the Epstein-Barr virus and how reactivation of chronic EBV infection can impact health. In this episode, Dr. Kasia Kines discusses the interplay of nutrition, toxic exposures, and chronic EBV.

Today on The Lab Report:

• 3:45 Meet Dr. Kasia Kines and hear about her path to functional nutrition
• 8:40 Using nutrition to navigate a toxic world
• 11:00 Diet therapeutics and choices
• 17:50 Why did Dr. Kines choose to specialize in EBV?
• 26:20 Chronic EBV as a hidden trigger, reactivation, and susceptibility
• 32:55 Therapies for management of EBV
• 36:30 Stress and sleep in reactivation illness
• 39:40 The Fireball 

Additional Resources:

EBVHelp

Kasia's website

The Epstein-Barr Virus Solution

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

See omnystudio.com/listener for privacy information.

In the last episode, we met Dr. Bryan Walsh, a naturopathic physician and well-renowned teacher with a unique way of approaching medicine. He challenged us to remain humbly skeptic and excitedly curious. He spends his time scouring the literature and redefining his approaches to learning, teaching, and practicing clinical medicine.

Today he discusses the latest science on some tried and true traditional biomarkers and the art of applying them clinically.

“There is a science to blood chemistry, but there’s also an art.” – Dr. Bryan Walsh

Today on The Lab Report:

• 4:00 Revisiting traditional blood chemistries and the importance of the reference range
• 7:20 Using albumin as an example to tell a clinical story
• 19:05 Why Dr. Walsh developed his online teaching: “Metabolic Fitness Pro”
• 22:40 Knowing basic biochemistry and physiology is key
• 25:30 Stop looking for the next big thing, take a fresh look at the basics

Additional Resources:

Metabolic Fitness Pro

drwalsh.com

Dr. Walsh's YouTube Channel

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

The history of medicine is riddled with shifting paradigms, disproven theories, and treatment protocols that may not be beneficial. Dr. Bryan Walsh is a naturopathic physician with a humble and deep curiosity which frames his unique approach to practicing medicine. By continually questioning the norm, he reminds us to dig deeper and follow the literature on topics that the medical community currently accepts as true.

Today’s episode is part one of our in-depth interview with Dr. Walsh where he discusses new ways of looking at detoxification and glucose regulation.

“We’ve been wrong before, what makes us think we’re right now. Let’s question things.” – Dr. Bryan Walsh

Today on The Lab Report:

• 2:40 Meet Dr. Bryan Walsh and hear about his overarching philosophies to medicine
• 8:45 Rethinking the concept of detoxification
• 13:35 Milk thistle and Curcumin: Friend or foe
• 16:05 Whole herb vs. Supercritical extracts
• 18:50 Missing conversations in glucose regulation
• 27:30 The importance of glycemic variability and ways to measure it

Additional Resources:

Metabolic Fitness Pro

drwalsh.com

Dr. Walsh's YouTube Channel

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

On our last episode, we introduced Dr. Brad Lichtenstein. Dr. Brad is a naturopathic physician who has spent his career teaching and practicing mind-body medicine, mindfulness, and meditation. This topic is crucial to optimal health, yet many patients find it intimidating and don’t know where to start. Today in part two of our interview, Dr. Brad dives into what mindfulness is, and how to cultivate mindful practices. Additionally, if you stick around to end of the show credits, Dr. Brad also leads us in a mindful meditation.

“Mindfulness means attention to the present moment without judgement or without elaboration. A lot of our suffering is because we are living in the judgement of something and missing the moment.” – Dr. Brad Lichtenstein

Today on The Lab Report:

• 3:05 What is mindfulness?
• 9:05 How can we incorporate mindfulness into our daily lives?
• 16:25 Attitudes regarding behavior change
• 22:30 Dealing with Zoom, social media, and devices
• 29:33 The Fireball: Dogs vs. Cats – which animal is more mindful?
• 34:30 Brad guides us in a ‘Mindfulness Meditation’

Additional Resources:

The Breath Space

Dr. Brad's TEDx Talk: Breathing Into Life

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and show not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.