The Moonshot Podcast

By X, The Moonshot Factory

The Moonshot Podcast chronicles the untold stories of innovation - both highs and lows - from inside Google’s Moonshot Factory. In Season 2, Captain of Moonshots Astro Teller sits down with a ne... more

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FAQs about The Moonshot Podcast:

How many episodes does The Moonshot Podcast have?

The podcast currently has 23 episodes available.

The Moonshot Podcast episodes:

April 01, 2026 The Moonshot Podcast S2, Episode 2: Coding The Natural World
This episode of The Moonshot Podcast dives into the future of biology, exploring how to harness life's "tiny factories" to solve humanity's biggest challenges.
Host Astro Teller sits down with Brad Zamft, CEO of Heritable Agriculture, to talk about programming plants to dramatically increase yield, pest, and drought resistance for a more sustainable food system.
Next Astro speaks with Relly Brandman from project A-Life about unlocking the manufacturing power of biology, using AI to create a "virtual cell" that shifts biomanufacturing from slow trial-and-error to a predictable engineering discipline for making materials like medicines, fuels, and textiles.
Hosted by Astro Teller, Captain of Moonshots, The Moonshot Podcast goes behind the scenes with creators and inventors trying to find radical solutions and breakthrough technologies to the world’s biggest problems. These are the untold stories of innovation from 15 years of Alphabet’s Moonshot Factory.
The Moonshot Podcast is a Pique Action production for X, The Moonshot Factory, produced in association with Blanchard House.

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40min
March 25, 2026 The Moonshot Podcast S2, Episode 1: Supercharging Human Health
The Moonshot Podcast is back!
In the season 2 premiere, X’s Captain of Moonshots Astro Teller explores how three X projects developed technology to transform the future of healthcare.
He first sits down with Kathryn Zealand and Anna Roumiantseva from Skip to hear about how the world’s first “e-bike for walking” evolved from their team’s mobility moonshot at X. They recount how an early prototype of Skip’s powered pants helped carry a colleague to top of the Salesforce Tower, and share how the product has developed since spinning out into an independent company (Astro even tries a pair on for size to see their progress firsthand).
Microelectronics expert Will Biederman then joins Astro for a conversation about the origins of Project Iris, a computerized contact lens designed to help measure diabetes risk, which laid the foundation for the continuous glucose monitors that millions of people use today. Finally, Astro chats with Verily CEO Stephen Gillet to hear about his mission to make precision healthcare accessible to anyone, anywhere, at any time.
0:00 - Intro
1:08 - Meet Kathryn Zealand and Anna Roumiantseva, Skip
1:57 - An “e-bike for walking”
2:35 - Why mobility needs a moonshot
3:42 - Limitations with current mobility solutions
6:19 - Criteria for the world’s first “movewear”
7:37 - Understanding the complexities of human motion
9:13 - How much weight Skip’s pants can carry
9:40 - Racing to the top of the Salesforce Tower
13:54 - Skip’s partnership with Arc’teryx
14:40 - The “kill criteria” for Skip’s moonshot
17:29 - Astro tries Skip’s pants on for size
18:55 - Meet Will Biederman, Project Iris
19:26 - Can a computerized contact lens help prevent diabetes?
20:19 - The potential worldwide impact of glucose monitoring
20:52 - Can tears help measure glucose?
22:50 - How to put a computer into a contact lens
24:11 - Project Iris’s early findings using glasses
25:20 - Fitting the “world’s smallest batteries” onto a contact lens
26:18 - A close-up view of the Project Iris contact lens
28:55 - How Project Iris transformed continuous glucose monitoring
31:18 - The origins of the Dexcom 7
32:08 - How glucose monitoring could lead to other health breakthroughs
32:55 - The future of everyday medical technologies
33:42 - Liftware’s “robot in a spoon” to counter tremors
34:16 - Meet Steven Gillett, Verily CEO
35:09 - Verily’s mission to democratize precision healthcare
36:30 - How Verily can aggregate a person’s entire medical history
39:05 - How Verily’s technology keeps private data secure
39:43 - Steve’s vision for how Verily can change the world
41:17 - What needs to happen in order to reach autonomous healthcare
42:27 - Conclusion
–
Hosted by Astro Teller, Captain of Moonshots, The Moonshot Podcast goes behind the scenes with creators and inventors trying to find radical solutions and breakthrough technologies to the world’s biggest problems. These are the untold stories of innovation from 16 years of Alphabet’s moonshot factory.
The Moonshot Podcast is a Pique Action production for X, The Moonshot Factory, produced in association with Blanchard House.

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45min
March 11, 2026 Season 2: The Moonshot Podcast Trailer
The Moonshot Podcast is back!
The Moonshot Podcast chronicles the untold stories of innovation - both highs and lows - from inside Google’s Moonshot Factory. In Season 2, Captain of Moonshots Astro Teller sits down with a new crop of moonshot takers exploring the next frontiers in health, biology, computing and more.
From energy kites and robotic pants, to sea fuel and digital immune systems, go behind the scenes with the inventors and creators working to turn "what if" into what’s next.
Available from March 25, wherever you get your podcasts.

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3min
January 13, 2026 Moonshot Podcast Deep Dive: Emily Ma on Solving Food Waste
In the ninth installment of the Moonshot Podcast Deep Dive series, Astro Teller and Emily Ma explore how to solve humanity’s food waste and hunger problems.
They discuss how Project Delta built an “air traffic control” system for the world’s surplus food. They also discuss the origins of Chorus, X’s moonshot to give every object a voice which is now focused on optimizing global supply chains using advanced sensors and orchestration software.

For more on the future of food waste, tune into Episode 6 of the Moonshot Podcast, “Trash to Treasure”: https://www.youtube.com/watch?v=WgRASA92Dco
Video Segmentation
00:00 - Introduction
01:38 - The origins of Emily’s passion for food waste
04:07 - Why food waste is such a big problem
07:09 - How Emily wound up at X
10:24 - Google Glass in early food waste prototypes
12:06 - Emily’s “waste audit” sifting through physical trash
15:08 - How food is wasted in every phase of the production process
20:36 - An “air traffic control” system for the world’s surplus food
23:54 - How X’s food waste technology helped tackle that surplus
29:25 - What the team learned by working in the field
30:40 - Food waste “nodes” to reroute surplus food
33:34 - Applying X’s food waste technology outside the U.S.
35:41 - The team’s early vision for a supply chain moonshot - Chorus
39:56 - How Chorus evolved from the Delta team
41:26 - How Delta graduated to Google
45:06 - Emily’s fondest moonshot memories
46:54 - The importance of play when taking moonshots

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50min
November 25, 2025 The Moonshot Podcast Deep Dive: Jason Rugolo on iyO and the Future of Audio Wearables
In the eighth installment of the Moonshot Podcast Deep Dive series, Astro Teller discusses the future of audio wearables with iyO Founder Jason Rugolo.
They discuss the many unexpected use cases for machine-mediated hearing, what it was like to build the world’s first audio computer and how to make audio wearables “cool.”

For more on the origins of iyO and the next generation of audio wearable technology, tune into Episode 9 of the Moonshot Podcast, “Supersenses”: https://www.youtube.com/watch?v=QlpF2QJNL5Y
00:00 - Introduction
02:17 - The first company Jason started at age 14
04:02 - How Jason came to X
06:40 - Jason’s earliest “fail fast” moonshot ideas
09:54 - The importance of being “the right amount too early”
12:45 - Radical idea for digital humans
14:59 - Early explorations into tele-video
18:49 - The original pitch for what became iyO
22:24 - Why designing great wearables for the ear is so hard
24:52 - Design considerations for audio wearables
29:41 - Making audio wearables “cool”
31:32 - The limitations of current in-ear devices
32:33 - The “superpowers” we’d have with machine-mediated hearing
35:30 - Building the first audio computer
36:30 - What the team’s first audio wearable looked like
38:01 - How audio wearables could help with translation
40:55 - The potential for wearables to protect from hearing loss
41:57 - The future of “hearing enhancement” apps
44:45 - The unexpected value of voice-to-audio interaction
48:34 - Astro’s “holy s**t” moment with audio wearables
52:26 - Why audio wearables need to change sound sources so quickly
55:47 - iyO’s public debut
57:23 - Surprising agentic AI use cases
58:50 - Physics conversations with the Einstein app using iyO
01:00:58 - Musical conversations with the iyO DJ app using iyO
01:01:51 - Jason’s hard-won lessons from taking moonshots

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1h 6min
October 13, 2025 Deep Dive: Ivy Ross & Isabelle Olsson on the Early Days of Google Glass
In this installment of the Moonshot Podcast Deep Dive series, Astro Teller explores the origins of Google Glass with designers Ivy Ross and Isabelle Olsson.
They discuss the unexpected design and tech challenges the team faced creating such a bold new form factor, the surprising ways people ended up wanting to use Glass, how their backgrounds in art influenced their approach, and the importance of timing when creating new technologies.
For more on Glass’s early days, tune into Episode 9 of The Moonshot Podcast, “Supersenses”: https://www.youtube.com/watch?v=QlpF2QJNL5Y
00:00 - Introduction
01:43 - How Isabelle wound up at X
03:37 - How Ivy came to X
07:25 - The big challenges Glass was solving
11:04 - The origins of the Glass Explorer Program
11:43 - Glass’s public debut
14:46 - Ivy’s earliest memories of Glass in action
18:37 - How art influenced the design of Glass
22:19 - Glass’s second generation design
27:20 - From sunglasses to monocles: Early design debates
31:30 - Surprising “fringe” uses of Glass in industry
34:33 - Reinventing Glass for industry
35:47 - Why timing matters
41:45 - Memorable team traditions
44:50 - When Glass moved from X to Google
47:41 - Early explorations with the Google Watch
49:37 - Lessons learned from taking moonshots

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53min
September 05, 2025 Deep Dive: David Guerena on the Future of Agriculture
In the sixth installment of our Moonshot Podcast Deep Dive series, X’s Captain of Moonshots, Astro Teller, discusses plant breeding and the future of agriculture with Agricultural Scientist, David Guerena. David works with The International Center for Tropical Agriculture (CIAT) — a partner of Mineral, X’s moonshot for computational agriculture. They discuss plant breeding, the challenges facing smallholder farmers around the world, and how the tools Mineral developed are helping plant breeders grow more resilient crops.
For more on Mineral’s impact on agriculture, check out Episode 4 of The Moonshot Podcast, “Feeding the World”: https://www.youtube.com/watch?v=eQS3lY6pRvY
And to learn more about how Mineral’s technology is being used by public plant breeding programs in the Global South, check out The Artemis Project: https://alliancebioversityciat.org/projects/artemis
00:00 - Introduction
1:09 - Why humans eat certain plants
3:20 - How plants have historically been domesticated
4:53 - The origins of plant breeding
6:52 - The changing face of plant breeding
8:42 - Gene banks that preserve genetic diversity
10:22 - Helping small farmers with plant breeding
12:33 - How David’s career started
14:00 - The process of identifying and cataloguing plants
23:32 - CIAT and CGIAR’s partnership with Mineral
26:13 - Mineral’s technology
32:59 - Unexpected findings from Mineral’s early days
38:40 - Solving for the biggest challenges in plant breeding
40:08 - Phenotyping 101
41:06 - The impact of Mineral’s technology
44:39 - The challenges of existing breeding systems
50:10 - The future of computational agriculture
57:00 - The impact of AI on plant breeders and farmers
59:19 - A surprising insight about bean cooking time
1:01:47 - The future of plant breeding
1:03:58 - David, finally, talks about Bruno

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1h 7min
August 22, 2025 Deep Dive: Jeff Dean on Google Brain’s Early Days
In the fifth installment of our Moonshot Podcast Deep Dive video interview series, X’s Captain of Moonshots Astro Teller sits down with Google DeepMind’s Chief Scientist Jeff Dean for a conversation about the origin of Jeff’s pioneering work scaling neural networks.
They discuss the first time AI captured Jeff’s imagination, the earliest Google Brain framework, the team’s stratospheric advancements in image recognition and speech-to-text, how AI is evolving, and more.
For more on X’s AI moonshots, check out Jeff on Episode 3 of The Moonshot Podcast, “Machines That Think”: https://www.youtube.com/watch?v=_jLPA8Qpc74
00:00 - Introduction
00:35 - What Jeff’s childhood was like
03:50 - The first “non-trivial” thing Jeff coded
05:02 - Jeff’s “love/hate” relationship with C++
06:59 - The first time AI captured Jeff’s imagination
10:40 - When neural networks fell “out of vogue”
12:24 - How Jeff made a career out of “starting over”
14:23 - The origins of Google Brain
17:30 - Critical components of scaling neural networks
18:43 - The earliest Google Brain framework
19:32 - How the team first built a 100x bigger neural network
22:04 - The cat video that started it all
25:02 - Google Brain’s major progress on image recognition
26:24 - Google Brain’s major progress on speech to text
27:29 - The origins of TensorFlow and TPUs
31:56 - Three breakthroughs in understanding language models
37:41 - Where Jeff thinks the world is headed
40:07 - The shift from “making things” to designing prompts
42:38 - How Jeff uses AI to enhance his own life
43:51 - Safety, security, and privacy in AI
50:26 - The future of understanding neural network behavior
53:34 - When computers are “smarter” than humans
56:52 - Jeff’s next-five-years plan

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59min
August 08, 2025 The Moonshot Podcast Deep Dive: Andrew Ng on Deep Learning and Google Brain
In the fourth installment of our Moonshot Podcast Deep Dive video interview series, X’s Captain of Moonshots Astro Teller sits down with Andrew Ng, the founder of Google Brain and DeepLearning.AI, for a conversation about the history of neural network research and how Andrew’s pioneering ideas led to some of the biggest breakthroughs in modern-day AI.
Hear about the origins of Google’s deep learning work, how Andrew’s teenage frustrations led him to pursue a career in machine learning and automation, and the work that led up to Google Brain’s infamous “cat video” paper.
For more on X’s AI moonshots, check out Andrew on Episode 3 of The Moonshot Podcast, “Machines That Think”: https://www.youtube.com/watch?v=_jLPA8Qpc74

00:00 - Introduction
03:30 - Andrew’s groundbreaking early theories about neural networks
08:16 - Why Andrew came to X with his ideas
10:30 - The unlikely history of neural network research
15:25 - Jeff Dean as Andrew’s “partner in crime”
17:16 - The origins of Google Brain’s neural networks
18:32 - Google Brain’s evolution in and out of hardware
22:01 - Google Brain’s innovation around transformers
24:36 - Google Brain’s earliest leaps forward in AI
28:24 - Google Brain’s graduation from X into Google
31:50 - What Andrew is up to these days
34:07 - Where the AI and machine learning field is going
35:19 - Andrew’s passion for education
36:51 - Why Andrew became interested in AI as a teenager
37:53 - AI’s democratizing effect on humanity
41:34 - How Andrew defines the term “artificial intelligence”
43:51 - Google Brain’s “cat video” coming out moment
45:51 - AI’s potential positive impact on the workforce
47:17 - Andrew’s favorite aspects of moonshot-taking

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52min
July 24, 2025 Deep Dive: Catie Cuan on Dancing and Living With Robots
In the third installment of our Moonshot Podcast Deep Dive video interview series, X’s Captain of Moonshots Astro Teller sits down with Dr. Catie Cuan, robot choreographer and former artist in residence at Everyday Robots, for a conversation about how dance can be used to build beautiful and useful robots that people want to be around.
Watch the video to hear how Catie and the Everyday Robots team transformed robotic motion into music, what it feels like when she’s dancing with a robot and why she’s “hyper-optimistic” about the future of robotics.
For more, check out Catie on Episode 5 of The Moonshot Podcast, “Living With Robots”: https://www.youtube.com/watch?v=aUcB73KgEVs
00:00 - Introduction
00:29 - Catie’s mission to make robots more humanistic and whimsical
02:12 - How Catie came to X and Everyday Robots
03:40 - Using dance to make robots less “robotic”
07:38 - Teaching robots human social cues
11:00 - Transforming robotic motion into sound with “music mode”
15:16 - Programming robots to “flock” together like animals
18:31 - How young kids interact with robots
20:15 - Catie’s own experience interacting with her robots
22:18 - Working with experts outside the field
24:36 - Designing robots to not look like “robots”
28:44 - Helping humanity face their visceral fear of robots
32:40 - The moonshot and legacy of Everyday Robots
35:42 - Catie’s advice for moonshot-takers
37:27 - Catie’s vision for what the future looks like

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42min

FAQs about The Moonshot Podcast:

How many episodes does The Moonshot Podcast have?

The podcast currently has 23 episodes available.

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