The Stem Cell Report with Janet Rossant

In this episode, we will talk about morphogenesis in embryo development, a process that in mammalians is known to show considerable plasticity. Understanding how this process is coordinated and how it responds to stress and physiological regulatory mechanisms provides us with a more complete picture of the regulation of mammalian development. We will talk with the authors of new research published in Stem Cell Reports on the regulation of embryo size and the timing of morphogenesis, critical early steps in embryonic development.

Show Notes
Guests
Lorenzo Orietti, PhD – Medical Advisor, Onco-Hematology Unit,  Amgen, Inc, (Italy)
Website: https://www.amgen.com/

Marta Shahbazi, PhD – MRC Laboratory of Molecular Biology, Cambridge, UK
Website: https://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/marta-shahbazi/
Twitter: @Marta_Shahbazi

Magdalena Zernicka-Goetz, PhD – Mammalian Embryo and Stem Cell Group and The Centre for Trophoblast Research, University of Cambridge, UK and the California Institute of Technology, US
Websites: http://zernickagoetzlab.pdn.cam.ac.uk/, https://zernickagoetzlab.caltech.edu/
Twitter: @ZernickaGoetz and @MZG_Lab

Host
Martin Pera, PhD – Editor-in-Chief, Stem Cell Reports and The Jackson Laboratory
Website: https://www.jax.org/research-and-faculty/faculty/martin-pera
Twitter: @martinperaJAX
Podcast Website: https://thestemcellreport.buzzsprout.com/

Supporting Resources
Embryo Size Regulates the Timing and Mechanism of Pluripotent Tissue Morphogenesis
DOI: https://doi.org/10.1016/j.stemcr.2020.09.004

 About Stem Cell Reports
Stem Cell Reports is the open access journal of the International Society for Stem Cell Research for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.
Twitter: @stemcellreports

About ISSCR
With nearly 4,000 members from more than 65 countries, the International Society for Stem Cell Research is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.
Twitter: @ISSCR 

ISSCR Staff
Keith Alm, Chief Operating Officer
Bethany Almon, Senior Manager of Integrated Marketing
Yvonne Fisher, Managing Editor, Stem Cell Reports
Kym Kilbourne, Director, Media and Strategic Communications
Jack Mosher, Senior Manager, Scientific Affairs
Nancy Witty, Chief Executive Officer

Voice Work
Julie Perlin
Ben Snitkoff

Music
@KonovalovMusic

In this episode Drs. Janet Rossant and Patrick Tam, join the podcast. They are experts in early embryonic development and authors of new Perspective article in Stem Cell Reports,  Opportunities and Challenges with Stem Cell-Based Embryo Models. Embryo modeling is a rapidly emerging area of science which can help advance the understanding of early development, especially human development where insight has been limited due to technical and ethical issues. The article is online now and will appear in the May 2021 special issue of the journal.

Show Notes

Guests
Janet Rossant, PhD - Hospital for Sick Children, the University of Toronto and the Gairdner Foundation. Website: https://lab.research.sickkids.ca/rossant/

Patrick Tam, PhD - University of Sydney, Australia
 Website: https://www.cmrijeansforgenes.org.au/researchers/patrick-tam

Host
Martin Pera, PhD – Editor-in-Chief, Stem Cell Reports and The Jackson Laboratory
Website: https://www.jax.org/research-and-faculty/faculty/martin-pera
Twitter: @martinperaJAX (https://twitter.com/martinperajax)
Podcast Website: https://thestemcellreport.buzzsprout.com/

Supporting Resources
Opportunities and Challenges with Stem Cell-Based Embryo Models
Website: https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(21)00082-5
DOI: https://doi.org/10.1016/j.stemcr.2021.02.002

NIH Blog
Website: https://osp.od.nih.gov/2021/03/11/human-embryo-development/

About Stem Cell Reports
Stem Cell Reports is the Open Access journal of the International Society for Stem Cell Research for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.
Website: https://www.cell.com/stem-cell-reports/home
Twitter: @stemcellreports (https://twitter.com/stemcellreports)

About ISSCR
With nearly 4,000 members from more than 60 countries, the International Society for Stem Cell Research is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.
Website: International Society for Stem Cell Research
Twitter: @ISSCR (https://twitter.com/isscr)

Acknowledgements

ISSCR Staff
Keith Alm, Chief Operating Officer
Bethany Almon, Senior Manager of Integrated Marketing
Yvonne Fisher, Managing Editor, Stem Cell Reports
Kym Kilbourne, Director, Media and Strategic Communications
Jack Mosher, Senior Manager, Scientific Affairs
Nancy Witty, Chief Executive Officer

Voice Work
Ben Snitkoff

Music
KonovalovMusic, @KonovalovMusic