Patients with cirrhosis are frequently transfused with platelets and plasma, yet the optimal role of these blood products may be poorly understood by ordering providers. It is important for pathologists to evaluate the available evidence supporting or refuting the use of these blood products in this population and be able to have conversations with gastroenterology colleagues about optimizing the transfusion plans for their mutual patients, explains Dr. Alexis Peedin in this CAPcast interview. Dr. Peedin led the development of a Clinical Pathology Improvement Program—also known as CPIP—on this topic (https://capatholo.gy/3hIpY7g).