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Most women have been told at some point that their menstrual cycle should dictate how they train, that fasted workouts are wrecking their hormones, or that muscle-building becomes nearly impossible after 40. In this episode, Dr. Sasha Hakman sits down with researcher and women's health expert Dr. Lauren Colenso-Semple to separate what the science actually shows from what the fitness industry is selling. They break down why cycle syncing isn't backed by the data, whether fasted training really matters, how much protein your body can actually use at once, and what's really true (and not true) about building muscle in perimenopause and menopause. If you've ever felt confused, discouraged, or like you needed to buy one more program to finally "get it right," this episode is for you.
In this episode, we cover:
Why the fitness industry profits from confusion — and how "cycle syncing" programs oversell the effect of hormones on your training
Fasted vs. fed training: does it affect fat loss, muscle growth, or strength adaptations? (Spoiler: no)
Low energy availability explained — who's actually at risk, and why it's different from simply training fasted
The truth about the "anabolic window" and post-workout protein timing
How much protein your body can actually use in one sitting, and why more isn't always better
Why weight training under stable, loaded conditions beats unstable-surface or "functional" exercises for building muscle
Understanding "the neighborhood of failure" — how close to failure you really need to train, and how to get started if you're intimidated by the weight room
Rep ranges myths: why sets of 5 and sets of 25 can build the same amount of muscle
Does the menstrual cycle affect training performance or adaptation? What the actual research says (not the extrapolated animal studies)
Hormonal birth control, "brain changes," and exercise capacity — what's real and what's not
Why so much of exercise science excluded women — and why that gap is closing faster than the internet gives it credit for
Testosterone and muscle growth: why massive differences in testosterone levels between men and women don't translate to massive differences in ability to build muscle
Can you make up for "lost time" if you didn't start lifting until your 40s, 50s, or later?
Menopause and muscle: does estrogen decline really make it harder to build muscle, and does hormone therapy change that?
Supplements that are actually worth your money — creatine dosing, why BCAAs are a waste, and why collagen is a poor protein source for muscle
Whey vs. pea protein, jumping for bone health, and whether weighted vests actually do anything
The single biggest myth stopping women from reaching their fitness goals
Follow Dr. Lauren Colenso-Semple! Instagram: @drlaurencs1
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
Thank you to our sponsors!
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You asked for it, and here it is. In this solo episode, Dr. Sasha Hakman walks through her own two IVF cycles in full detail — the exact medications, doses, trigger decisions, lab outcomes, and the reasoning behind every choice she made. As a reproductive endocrinologist who has navigated IVF both as a clinician and a patient, she brings a level of transparency you rarely get from a doctor. From a purely elective embryo freeze at 32 to a second retrieval at 37, this episode breaks down what actually goes into building a family through IVF — and helps you understand your own protocol along the way.
In this episode, we cover:
Follow Dr. Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingpod
YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more!
If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week.
If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
Thank you to our sponsors!
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Endometriosis affects at least 1 in 10 women, yet the average patient waits years for a diagnosis — often after being told their pain is normal. In this episode, Dr. Sasha Hakman sits down with board-certified OB/GYN and endometriosis surgeon Dr. Mallory Stuparich to break down what endometriosis actually is, why it's now understood as a systemic immune and neuro-inflammatory condition rather than a purely hormonal one, and how patients can push back when they're being dismissed. If you've ever been told your pain is "just part of being a woman," this episode is for you.
In this episode, we cover:
What endometriosis actually is — and why "endometrial-like tissue" outside the uterus is now understood as part of a systemic neuro-inflammatory and neuro-immune disorder, not just a hormonal one
Why endometriosis so often overlaps with mast cell activation, POTS, Ehlers-Danlos syndrome, autoimmune conditions, and migraines
The leading theories on what causes endometriosis, and why retrograde menstruation alone doesn't explain it
Normal period pain vs. abnormal period pain — and the questions to ask yourself to know the difference
Red flag symptoms beyond pelvic pain: GI issues (painful bowel movements, incomplete emptying, bleeding), bladder urgency, pelvic floor dysfunction, painful sex, and brain fog
Why the amount of pain a patient feels doesn't always correlate with how much disease is actually present
What a real diagnostic workup looks like, and why a "normal" ultrasound or MRI does not rule out endometriosis
Post-surgical hormone therapy — why suppression after excision matters, and who isn't a candidate
Adenomyosis explained: what it is, how it differs from fibroids, and treatment options including adenomyomectomy, uterine artery embolization, and microwave ablation
The links between endometriosis, infertility, and miscarriage — including why 50% of women with endo do not experience infertility
Recurrence after excision surgery, and why what looks like "recurrence" is often incomplete removal the first time around
Lightning round: Is endometriosis genetic? Can you have it with completely normal labs and imaging? Does a hysterectomy cure it? Can it still affect you after menopause?
Follow Dr. Mallory Stuparich! Instagram/social: @MalloryStuparichMD
Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
Thank you to our sponsors!
Head to bioptimizers.com/drsasha and use code DRSASHA
try OneSkin with 15% off using code DRSASHA at oneskin.co/DRSASHA
Head to vitaclean.co and use code DRSASHA for 20% off Shower head Starter Kits
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Pregnancy loss affects 15–25% of clinically recognized pregnancies, yet so many people are left without answers — or without hope. In this solo episode, Dr. Sasha Hakman breaks down everything you need to know about miscarriage and recurrent pregnancy loss: the five major causes, how each one is diagnosed, what treatment actually looks like, and which lifestyle factors are (and aren't) worth worrying about. If you've experienced a loss and are searching for answers, this episode is for you — and remember, it is not your fault.
In this episode, we cover:
Follow Dr. Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingpod
YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
Thank you to our sponsors!
Head to cozyearth.com and use my code DRSASHA for an exclusive 20% off.
Use code DRSASHA at carawayhome.com for 10% off
Subscribe, rate, and review if this episode helped you — and share it with someone who needs to hear it. New episodes drop every Wednesday.
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In this solo episode, Dr. Sasha dives into one of the most requested topics on the podcast: trying to conceive and being pregnant after 40. She cuts through the noise of misleading celebrity headlines and online misinformation to give you a clear, honest, and compassionate look at the biology, statistics, and real options available to you.
In This Episode, You'll Learn:
Why more women are having babies in their 40s than ever before — and why that's a good thing
The biology of egg aging: how quantity and quality decline, and what's actually happening at the cellular level (mitochondrial dysfunction, meiosis errors, chromosomal abnormalities)
What your AMH level means after 40, and why high ovarian reserve can be a game-changer
Natural fertility rates by age and when ASRM guidelines say to seek immediate care
IVF success rates broken down by age: from 43% live birth rate under 35, all the way down to 3% over 42
Follow Dr. Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingpod
YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
Thank you to our sponsors!
Save 20% Off Honeylove by going to honeylove.com/DRSASHA! #honeylovepod
For a limited time, try OneSkin with 15% off using code DRSASHA at oneskin.co/DRSASHA.
Head to AirDoctorPro.com and use promo code DRSASHA to get $250 off select AirDoctor air purifiers, including the 3500, 4000, and 5500 models
New episodes of Trying with Dr. Sasha Hakman drop weekly. If this episode resonated with you, leave a review and share it with someone who needs a doctor they can trust in their corner.
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If you've ever gone through a failed embryo transfer and wondered why , this episode is for you. Dr. Sasha sits down with Jeremy Grushcow, co-founder and CEO of Juniper Genomics, to break down a groundbreaking advancement in IVF: whole genome and transcriptome embryo testing.
Jeremy holds a PhD in molecular genetics and cell biology from the University of Chicago, along with a law degree, and has published research in DNA repair, cancer, gene therapy, bioethics, and patent law. He's building the technology that could change the odds for IVF patients everywhere.
In this episode, we cover:
Follow Dr Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingwithdrhakman
YouTube: @sashahakmanmd
Resources & Links:
Juniper Genomics website: junipergenomics.com
Instagram: @junipergenomics
Want to receive my weekly newsletter?
Sign up at sashahakmanmd.com/newsletter to receive updates, answers to Q&A and more !If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every 2 weeks.
If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
If this episode helped you, the best thing you can do is subscribe, rate, review, and share it with a friend. So many women deserve this information, help get it to them. Episodes drop every Wednesday.
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What does it actually mean to try as a woman, as a patient, as a person navigating a healthcare system that wasn't built with you in mind? In this first solo episode of the newly rebranded Trying with Dr. Sasha Hakman, Dr. Sasha shares why she changed the name, what this podcast is really about, and who it's for.
She opens up about the conversation that sparked the rebrand, the reality of practicing medicine in a field driven by IVF incentives, and why she started a podcast in the first place. She also shares a personal update (18 weeks pregnant with baby #3!) and answers one of the most frequently asked questions from her community: how do you know if you can actually trust your doctor?
In This Episode, You'll Learn:
Why Dr. Sasha rebranded from Trying to Conceive to Trying with Dr. Sasha Hakman
What a Reproductive Endocrinologist actually specializes in beyond IVF
How to know if your doctor's IVF recommendation is truly evidence-based or financially motivated
The green flags to look for when choosing a fertility doctor or clinic
How to read online reviews and pregnancy success rates without being misled
What actually makes an exceptional doctor
Follow Dr. Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingpod
YouTube: @sashahakmanmd
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
Thank you to our sponsors!
head to http://www.bioptimizers.com/DRSASHA and use my exclusive code DRSASHA to get 15% off any order
Use our exclusive link to save 20% off Honeylove at honeylove.com/DRSASHA
Go to ogee.com/DRSASHA and use code DRSASHA for 20% off.
New episodes of Trying with Dr. Sasha Hakman drop weekly. If this episode resonated with you, leave a review and share it with someone who needs a doctor they can trust in their corner.
Learn more about your ad choices. Visit megaphone.fm/adchoices
Are you being told to stop exercising while trying to conceive or going through IVF? You're not alone and according to today's guest, you're also likely being given advice that isn't backed by science.
In this episode, Dr. Shannon joins us for a conversation that is equal parts empowering and eye-opening. As both a physical therapist and a patient who exercised throughout her own fertility journey, she brings a rare dual perspective to the table. She and host Dr. Sasha take on the pervasive fear around exercise during fertility treatment, break down why the "rest and raise your legs" mentality is outdated (and potentially harmful), and share a practical, research-backed framework for building and maintaining muscle at every stage of the journey.
Whether you're in the thick of fertility treatments, newly pregnant, postpartum, or just trying to understand your body better, this episode is packed with actionable guidance and a refreshing dose of truth.
In This Episode, You'll Learn:
Why most doctors tell patients to stop exercising during IVF — and why there's no evidence behind it
How months of exercise restriction can harm your long-term recovery and postpartum body
The REPS Framework: the four principles that actually build muscle while TTC or pregnant
What "training to failure" really means — and why it's safe even during fertility treatment
Why you need to train near failure just to maintain the muscle you already have
How to choose exercises that actually target the right muscles (and why combo moves fall short)
Protein targets for TTC and pregnancy, and how to realistically hit them
When HIIT is okay to keep during TTC — and when it may be hurting your chances
How to safely return to exercise postpartum without setting yourself back
One simple trick to improve your form without a personal trainer
Follow Dr. [email protected] @evlofitness
Follow Dr Sasha!TikTok: @sashahakmanmdInstagram: @sashahakmanmd @tryingtoconceivepodYouTube: @tryingtoconceivepod
Resources Mentioned:
Evlo App (Dr. Shannon's fitness app) — Use code DRSASHA for 6 weeks free (first 2-week trial + 1 month at $0)
American College of Obstetricians and Gynecologists (ACOG) — exercise contraindications list available on their website
Want to receive my weekly newsletter?
Sign up at sashahakmanmd.com/newsletter to receive updates, answers to Q&A and more!If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every 2 weeks.
If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
New episodes of Trying to Conceive with Dr. Sasha Hakman drop weekly. If this episode resonated with you, leave a review and share it with someone on their fertility journey.
Learn more about your ad choices. Visit megaphone.fm/adchoices
In this solo episode, Dr. Sasha goes deep on one of her most-requested topics: endocrine disrupting chemicals (EDCs). What they are, where they're hiding, how they affect your hormones and fertility, and exactly what you can do about it.
As a reproductive endocrinologist and infertility specialist, she brings both clinical expertise and personal practice to this conversation. This episode is grounded in evidence-based research, including a 136-page scientific statement from the Endocrine Society, and is designed to inform, not alarm.
In This Episode, You'll Learn:
What the endocrine system is and why hormones are the body's "keys and locks"
The definition of EDCs and why exposure is considered a global public health crisis
Why even tiny exposures can have outsized health impacts (it's not always dose-dependent)
The major classes of EDCs to know: BPA/bisphenols, phthalates, PFAS (forever chemicals), parabens, glyphosate, heavy metals, and triclosan and where each one hides
The 4 mechanisms EDCs use to disrupt your hormones - including epigenetic modification that can be passed down through generations
Why in utero exposure is the most critical window, and what effects have been linked to fetal EDC exposure (including hypospadias, cryptorchidism, diminished egg reserve, and premature ovarian insufficiency)
How EDC exposure impacts puberty, fertility, and the TTC window specifically - including the finding that phthalate metabolites were detected in the follicular fluid of 99% of women undergoing egg retrieval
The link between EDC exposure and sperm count decline (down 50% in 50 years, per Dr. Shanna Swan's research)
Health risks in adulthood: endometriosis, PCOS/PEMOS, diminished ovarian reserve, thyroid dysfunction, breast cancer, prostate cancer, and more
The Tier 1 vs. Tier 2 framework for prioritizing what to eliminate first
Why "BPA-free" is a marketing gimmick and what to look for instead
Why "unscented" ≠ fragrance-free - and what that means for your products
Why fragrance is banned entirely in IVF embryology labs (and what that tells us)
A study showing BPA urinary levels drop significantly after just 3 days of cutting out heated plastic
Follow Dr Sasha!
TikTok: @sashahakmanmd
Instagram: @sashahakmanmd @tryingtoconceivepodYouTube: @tryingtoconceivepod
Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter to receive updates, answers to Q&A and more!
If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every 2 weeks.
Thank you to our sponsors!
Head to AirDoctorPro.com and use promo code DRSASHA to get $250 off select AirDoctor air purifiers.
Head to cozyearth.com and use my code DRSASHA for an exclusive 20% discount.
New episodes of Trying to Conceive with Dr. Sasha Hakman drop weekly. If this episode resonated with you, leave a review and share it with someone on their fertility journey.
Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Sasha Hakman is finally joined by her husband, Dr. Eryk Hakman. In this honest, funny, and surprisingly emotional episode, Sasha and Eryk sit down together for the first time to share the full story: how they met on labor and delivery, why Eryk almost didn't commit, and what it has really been like to navigate three rounds of IVF as a couple, including a failed embryo transfer that hit them both harder than either expected. Eryk opens up about feeling powerless in a process driven by his wife's expertise, what grief looked like from the partner's side, and what finally convinced him to say yes to baby number three. They wrap it all up with a fertility quiz that is equal parts educational and hilarious.
In This Episode, You'll Learn:
Follow Dr Sasha!
Want to receive my weekly newsletter?
If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every 2 weeks. If you're interested in becoming a patient go to sashahakmanmd.com to learn more!
Thank you to our sponsors:
Learn more about your ad choices. Visit megaphone.fm/adchoices
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