Answers from the Lab

Unique pediatric evaluation targets relevant autoimmune/CNS antibodies: Andrew McKeon, M.B., B.Ch., M.D.


Listen Later

(00:31)
 Could you tell us a little bit about yourself and your background?

(01:15)
 Can you give us a little understanding of this disease state and why a tailored evaluation for pediatric patients is important?

(02:47)
 What makes it more challenging to diagnose a pediatric autoimmune neurological disorder?

(03:32)
 Is the tailored evaluation necessary because different antibodies are evaluated?

(04:08)
 How common are these disorders in pediatric patients?

(04:40)
 How does our assay for adults differ from the pediatric assay?

(05:17)
 Do we evaluate for the ANNA-1 paraneoplastic antibody in both children and adults?

(05:59)
 Are our decisions on which antibodies to include based on our clinical experience?
 
(06:46)
 Which patients would this kind of testing be appropriate for?

(07:29)
 Should antibody testing be ordered early in the process of differential diagnosis?

(08:29)
 Do other disorders mimic these autoimmune disorders?

(09:00)
 What do test results mean in terms of next steps for physicians and patients?

(09:55)
 What are the most critical antibodies to test for in this pediatric population?

(10:30)
 Is it important for physicians to send both serum and CSF samples?

(10:48)
 In what specimen type is MOG most readily detected?

(11:18)
 What are the repercussions of not using a tailored evaluation?

(13:04)
 Do we use any patterns we see in test results to build future evaluations?

(14:15)
 Does a tailored evaluation mean faster test results?

(15:21)
 Are there any other key takeaways that you want to share with physicians to help them understand the importance of this evaluation and how it can be used in their clinical practices?

...more
View all episodesView all episodes
Download on the App Store

Answers from the LabBy Mayo Clinic Laboratories

  • 5
  • 5
  • 5
  • 5
  • 5

5

21 ratings


More shows like Answers from the Lab

View all
Freakonomics Radio by Freakonomics Radio + Stitcher

Freakonomics Radio

32,245 Listeners

HistoryExtra podcast by Immediate

HistoryExtra podcast

3,214 Listeners

20/20 by ABC News

20/20

11,952 Listeners

48 Hours by CBS News

48 Hours

10,980 Listeners

The Daily by The New York Times

The Daily

113,290 Listeners

Up First from NPR by NPR

Up First from NPR

56,909 Listeners

Dateline NBC by NBC News

Dateline NBC

47,431 Listeners