Carter is an extremely active little boy. A typical day for him would be spent outside climbing, running, riding his bike, or just "getting into it" as he puts it. He attends Wilkins Elementary School, Amherst, NH. In September 2015, during the beginning of first grade his mom and dad noticed that he was slowing down and complaining of knee pain. They brought him to the doctor and she immediately sent him for x-rays. The next day the x-rays revealed a tumor on his lower left femur. He was diagnosed with fibroblastic osteosarcoma. Carter is following the MAP chemotherapy treatment commonly used to treat osteosarcoma. This includes 29 weeks of chemotherapy. In addition, Carter had surgery on January 8, 2016 to remove the tumor on his left femur and to have rotationplasty preformed. The family chose rotationplasty because it was the surgery option that allowed Carter to continue living his active lifestyle. Carter's family includes his parents, Danielle and John and Marble, his cat. Carter's hobbies include climbing anything, riding bikes, playing hockey, swimming, going to the beach, sailing, kayaking, spending time with his cat Marble, skiing, playing jokes on people, making inventions, hanging out in his treehouse, going in the swamp in his backyard, building Legos, playing with remote control cars, and just being outside! Carter has become very interested in the process of making his prosthesis and is thinking he wants to become a prosthetist. Carter has become friends with a young man named Jack who had Carter's surgery 10 years ago. Jack has become an amazing role model for Carter. He truly looks up to Jack and his friendship with Jack has made this journey easier for Carter to understand and keep positive. Katherine Janeway, MD, is clinical director of the Solid Tumor Clinic at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. Her research focuses on the genomics of pediatric solid tumors and bringing the benefits of precision medicine to children with these cancers. Dr. Janeway also leads clinical trials of new therapies for pediatric sarcomas and serves as the lead pediatric investigator for Profile, Dana-Farber’s genotyping study, which has enrolled and sequenced tumor samples from 500 pediatric patients. Dr. Janeway is extremely knowledgeable and seeks input from other colleagues to ensure she finds the best possible treatment paths for her patients. She treated Carter and his family like team members in Carter's care. The family were always listened to and their concerns were taken into consideration. They always looked forward to their meetings with Dr. Janeway. Especially on days when they may have been feeling worried she always reassured them that she had a plan. They have full confidence in her and know that Carter