We talk about the mathematics of pain and pleasure. Lots here if you want to understand the science of bliss without the dogma that comes from the traditional understanding of pleasure and pain.

Wireheading Done Right: https://qualiacomputing.com/2016/08/20/wireheading_done_right/   The Neuroscience of Meditation: https://opentheory.net/2018/12/the-neuroscience-of-meditation/   Glossary: https://qualiacomputing.com/2019/08/21/glossary-of-qualia-research-institute-terms/