Dr. Roy Perlis, editor-in-chief of JAMA AI and psychiatrist-researcher at Mass General Brigham, joins to explore the evolving intersection of artificial intelligence and healthcare. Drawing on his deep experience and expertise working in neural networks, genetics, and electronic health records, Roy outlines where AI is genuinely delivering — like ambient scribes and clinical decision support — while urging clinicians to stay skeptical, look for clinically meaningful outcomes, and resist the de-skilling that comes with over-reliance on automation. We also discuss mental health stigma among physicians, the promise and peril of AI chatbots in psychiatric care, and the looming psychiatry workforce crisis, leaving listeners with one essential question: will AI actually make things better?

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