Does intelligent life exist elsewhere in the universe? The question has captivated us for centuries, but despite decades of searching it remains frustratingly unanswered. Every so often a curious signal appears — fossilized structures in a meteorite, say, or an unusual gas in an exoplanet’s atmosphere — and for a moment it seems possible that we are not alone before the excitement gives way to a more mundane explanation. 

So what would it actually take to find life in the cosmos — and how would we know when we saw it?

David Kipping, an astronomer at Columbia University, has spent his career finding better ways to answer these questions. His approach is statistical: rather than chasing individual detections, he develops mathematical frameworks for reasoning about where habitable worlds are likely to exist and how confidently we can interpret the signals they produce. In this episode of The Joy of Why, Kipping joins co-host Janna Levin to discuss efforts to frame one of humanity’s oldest existential questions as a tractable scientific problem, why biosignatures have proved so difficult to interpret, and why he believes exomoons may be an overlooked place to search for life.