A new mishnah! One who has intent to handle the food of an offering to be eaten at the wrong time or wrong location - or parts of the animal that are not customarily eaten - with a measurement of a kezayit, an olive's worth. But note that less than an olive's worth of something eaten does not combine with less than an olive's worth that is burned in the wrong place or the wrong way. Plus, many other cases, including a fetus or eggs in a female animal at the time of slaughter. The Gemara on the mishnah begins with a statement from the amora R. Elazar, which is unusual. Also, further discussion of intent in such a way that the result is pigul - and pigul itself carries a karet punishment.