Teriflunomide (Aubagio) is approved as disease-modifying therapy for mild to moderate RRMS from 10 years of age.

You can find the full article to read on my blog: https://ms-perspektive.com/70-teriflunomide

This time it’s about teriflunomide, which is known under the trade name Aubagio. The immunotherapy is used for mild to moderate courses of relapsing forms of MS.

Teriflunomide also has a broader mechanism of action and is one of the immunomodulating drugs. Please remember that I can only provide an overview here. Ask your neurologist and MS nurse for detailed advice on choosing the right therapy for you. They should know your complete state of health and be aware of your goals, wishes, fears and preferences.

Table of Contents

• General Information
• How is teriflunomide (Aubagio and generics) classified in immunotherapies?
• What is teriflunomide (Aubagio) approved for?
• What is the situation for special patient groups?
• Who should avoid teriflunomide?
• How does teriflunomide works?
• How is it taken?
• How effective is teriflunomide (Aubagio and generics)?
• Risks and side effects of teriflunomide (Aubagio and generics)
• Vaccinations
• Sources
• Final note

Sources

I used the following sources to create the content:

• Quality manual of the KKNMS on teriflunomide (Aubagio)
• MS-Selfie Infocards by Prof. Dr. Gavin Giovannoni 
• German Multiple Sclerosis and Fertility Registry (DMSKW) 
• Information from the German interview with Prof. Dr. Barbara Kornek on pediatric MS 
• DMSG information on teriflunomide
• DECIMS information on teriflunomide

Final note

Please remember, there is no one great medication that helps everyone, but it must always be weighed up what suits a particular person best. Other illnesses, personal goals and preferences must also be taken into account. Your neurologist and MS nurse are the right persons to talk to and can make individual recommendations. This article is for information purposes only and does not constitute a recommendation. What helps one person may not help another.

I hope that, together with your neurologist and MS nurse, you will quickly find the right immunotherapy for you. And that you can lead a fulfilled, happy and self-determined life with MS, supported by a healthy lifestyle and a dose of fortune.

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You may also want to look at the posts on the other DMTs:

• Dimethyl fumarate (Tecfidera) and diroximel fumarate (Vumerity)
• Glatiramer acetate (Copaxone, Brabio)
• Interferon-beta (Avonex, Betaferon, Extavia, Plegridy, Rebif)

See you soon and try to make the best out of your life, Nele

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