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Exocrine Pancreatic Insufficiency (EPI) is a condition caused by damage to the pancreas that results in reduced capability to produce or deliver digestive enzymes which break down fats, carbohydrates or proteins — or to a decrease in the enzyme activity in the small intestine. EPI is most commonly associated with chronic pancreatitis (in adults), cystic fibrosis (in children), diabetes (both type 1 and type 2) and other etiologies such as acute pancreatitis, pancreatic cancer or resection, celiac and Crohn’s disease. Consequently, individuals with EPI may suffer malnutrition and fat-soluble vitamin deficiency; loss of bone mass; growth and immune deficiencies; and may experience poorer outcomes such as longer hospital stays and lower survival rates of underlying medical conditions secondary to malnutrition.
Listen to guests Kimberly Kearns MS, APRN, ANP-BC and Amy Stewart FNP-C discuss EPI on this episode of the official podcast of the American Association of Nurse Practitioners® (AANP), NP Pulse: The Voice of the Nurse Practitioner®
Additionally, two new tools are also available on AANP’s Tools and Resources page in both the Gastroenterology and in the Pulmonology and Respiratory therapeutic areas:
Pancreatic Enzyme Replacement Therapy (PERT) – Patient Guide to diet and lifestyle modifications, and to the self-administration of PERTs to help reduce symptoms including gas, bloating, abdominal pain and diarrhea caused by undigested food in the gut.
Diagnosing and Managing Exocrine Pancreatic Insufficiency (EPI) – Provider Resource including evaluation of symptoms and common high-risk conditions, diagnostic testing and management goals combining diet, lifestyle and therapies to reduce symptoms and improve quality of life.
Your voice counts here: EPI Podcast Follow Up Survey (surveymonkey.com)
**This podcast is unaccredited.
By American Association of Nurse Practitioners (AANP)4.7
7676 ratings
Exocrine Pancreatic Insufficiency (EPI) is a condition caused by damage to the pancreas that results in reduced capability to produce or deliver digestive enzymes which break down fats, carbohydrates or proteins — or to a decrease in the enzyme activity in the small intestine. EPI is most commonly associated with chronic pancreatitis (in adults), cystic fibrosis (in children), diabetes (both type 1 and type 2) and other etiologies such as acute pancreatitis, pancreatic cancer or resection, celiac and Crohn’s disease. Consequently, individuals with EPI may suffer malnutrition and fat-soluble vitamin deficiency; loss of bone mass; growth and immune deficiencies; and may experience poorer outcomes such as longer hospital stays and lower survival rates of underlying medical conditions secondary to malnutrition.
Listen to guests Kimberly Kearns MS, APRN, ANP-BC and Amy Stewart FNP-C discuss EPI on this episode of the official podcast of the American Association of Nurse Practitioners® (AANP), NP Pulse: The Voice of the Nurse Practitioner®
Additionally, two new tools are also available on AANP’s Tools and Resources page in both the Gastroenterology and in the Pulmonology and Respiratory therapeutic areas:
Pancreatic Enzyme Replacement Therapy (PERT) – Patient Guide to diet and lifestyle modifications, and to the self-administration of PERTs to help reduce symptoms including gas, bloating, abdominal pain and diarrhea caused by undigested food in the gut.
Diagnosing and Managing Exocrine Pancreatic Insufficiency (EPI) – Provider Resource including evaluation of symptoms and common high-risk conditions, diagnostic testing and management goals combining diet, lifestyle and therapies to reduce symptoms and improve quality of life.
Your voice counts here: EPI Podcast Follow Up Survey (surveymonkey.com)
**This podcast is unaccredited.

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