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In this episode of Real Life Pharmacology, we take a closer look at several NSAIDs that are commonly encountered in clinical practice: nabumetone, diclofenac, meloxicam, piroxicam, etodolac, indomethacin, sulindac, and ketorolac.
These medications may all belong to the same general class, but they have important differences in dosing, adverse effects, drug interactions, and clinical use. We’ll discuss which NSAIDs tend to be more COX-2 selective, which ones carry significant gastrointestinal or cardiovascular concerns, and why some agents are used much more cautiously than others.
We’ll also cover practical pharmacology pearls for medications such as indomethacin, which is commonly used for acute gout, ketorolac, which is generally reserved for short-term pain management, and diclofenac, which has important cardiovascular considerations.
Whether you’re studying for a pharmacology exam, working with patients, or simply want to strengthen your knowledge of NSAIDs, this episode focuses on the clinically relevant points you need to know about these eight medications.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
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Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Aspirin, ibuprofen, naproxen, and celecoxib are some of the most commonly used NSAIDs, but they are not interchangeable when it comes to safety, indications, and patient-specific risks. In this episode of Real Life Pharmacology, we compare these four medications and highlight the key differences pharmacists and other healthcare professionals need to know.
We’ll review how NSAIDs work, including COX-1 and COX-2 inhibition, and discuss their effects on pain, inflammation, platelets, the gastrointestinal system, kidneys, cardiovascular system, and fluid balance. We’ll also compare the GI, cardiovascular, renal, and heart failure risks of aspirin, ibuprofen, naproxen, and celecoxib.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
NAPLEX Study Materials
BCPS Study Materials
BCACP Study Materials
BCGP Study Materials
BCMTMS Study Materials
Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
On this podcast episode, I cover the basics of NSAIDs, including how they work, what they are used for, significant drug interactions, and what adverse effects are important to monitor. I’ll educate about some of the major risks associated with NSAIDs and what I look out for as a practicing pharmacist.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
NAPLEX Study Materials
BCPS Study Materials
BCACP Study Materials
BCGP Study Materials
BCMTMS Study Materials
Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
In this episode of Real Life Pharmacology, we’re taking a closer look at three unique opioids: tramadol, tapentadol, and meperidine. These medications have some important differences in their mechanisms, clinical uses, drug interactions, and safety concerns. We’ll review the key pharmacology and practical clinical pearls you should know when using these opioids in real-world practice.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
NAPLEX Study Materials
BCPS Study Materials
BCACP Study Materials
BCGP Study Materials
BCMTMS Study Materials
Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
In this episode of Real Life Pharmacology, we’re taking a closer look at two unique opioids: methadone and buprenorphine. Both medications have important roles in pain management and opioid use disorder, but their pharmacology, dosing, drug interactions, and safety considerations are quite different. We’ll review the key clinical pearls you need to know when using these medications in real-world practice.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
NAPLEX Study Materials
BCPS Study Materials
BCACP Study Materials
BCGP Study Materials
BCMTMS Study Materials
Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
On this podcast episode, we will explore the most important practice pearls of codeine and fentanyl. Both medications are opioids, but codeine is frequently found in combination with acetaminophen. Fentanyl has numerous unique dosage forms, including the transdermal formulation which is a source of frequent test questions. I break these two medications down in this podcast episode.
In Part 2 of my series on opioids, I cover hydromorphone, oxycodone, and oxymorphone. Hydromorphone and oxycodone are two opioids that are used frequently in clinical practice, and I will discuss what makes them unique, in addition to numerous other practice pearls and test prep nuggets. Enjoy the podcast and be sure to share it with friends, colleagues, and students!
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
NAPLEX Study Materials
BCPS Study Materials
BCACP Study Materials
BCGP Study Materials
BCMTMS Study Materials
Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
On part 1 of opioids, I’ll discuss morphine, morphine equivalents, conversion, and hydrocodone. The pharmacokinetic differences will be important between opioids, as well as the dosage forms. I hope you enjoy this podcast episode and share it with your friends!
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
NAPLEX Study Materials
BCPS Study Materials
BCACP Study Materials
BCGP Study Materials
BCMTMS Study Materials
Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
On this episode of the Real Life Pharmacology podcast, I’m going to cover important practice pearls on skeletal muscle relaxants. Important medications that will be covered in this podcast include baclofen, cyclobenzaprine, tizanidine, and diazepam.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
NAPLEX Study Materials
BCPS Study Materials
BCACP Study Materials
BCGP Study Materials
BCMTMS Study Materials
Nursing Pharmacology Review Course
Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)
Guide to Drug Food Interactions (Amazon Best Seller)
Pharmacy Technician Study Guide by Meded101
Pharmacy Technician Bootcamp (PTCB Exam Prep Course) – 4.8/5 star course rating
Abdominal cramping and intestinal spasms are common complaints in patients with conditions such as irritable bowel syndrome (IBS). Two of the most frequently prescribed medications for these symptoms are dicyclomine and hyoscyamine. These medications work by blocking muscarinic receptors, reducing smooth muscle contractions in the gastrointestinal tract and helping relieve painful spasms.
While these medications can be effective, they are not without risks. Because of their anticholinergic effects, patients may experience dry mouth, constipation, blurred vision, dizziness, and urinary retention. Older adults are particularly susceptible to these adverse effects, making careful patient selection and monitoring especially important. Patients with benign prostatic hyperplasia (BPH), glaucoma, or cognitive impairment may be at higher risk for complications.
In this episode of the Real Life Pharmacology podcast, we’ll review how dicyclomine and hyoscyamine work, discuss their most common clinical uses, compare their adverse effect profiles, and highlight practical education points to help optimize safe and effective use.
Huge thank you to our sponsor – Mechanism of Action Podcast; Go check them out on all your favorite podcast platforms!
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
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