On this top 200 drugs podcast, we are covering medications 141-145. Raltegravir, ustekinumab, meloxicam, infliximab, and Nighttime Cold and Flu are the medications that are covered on this episode.

Raltegravir is an integrase inhibitor that is used to manage HIV infection and may also be used for post-exposure prophylaxis.

Ustekinumab is a monoclonal antibody that can help reduce inflammation by binding interleukins.

Meloxicam is an NSAID used for pain and anti-inflammatory purposes. GI bleeding risk is a top adverse effect to monitor for.

Infliximab is a monoclonal antibody that can be used for autoimmune disorders such as psoriatic arthritis, rheumatoid arthritis, ulcerative colitis, and Crohn’s disease.

Nighttime Cold and Flu medication is a combination product that often includes acetaminophen, dextromethorphan, and doxylamine.

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On this episode, I cover cinacalcet, solifenacin, haloperidol, hydrocortisone (focused on topical), and insulin NPH.

Cinacalcet is a calcimimetic medication that can be helpful in hyperparathyroidism and useful for managing hypercalcemia.

Solifenacin is a urinary antimuscarinic used primarily for overactive bladder. It is an anticholinergic medication that can be problematic in our geriatric patients.

Haloperidol is a first generation antipsychotic that has a high incidence of EPS relative to many newer antipsychotics.

Hydrocotorisone is one of the most common topical corticosteroids that can be used to reduce inflammation and redness from skin reactions.

Insulin NPH is an intermediate acting insulin that is meant to be given on a routine basis. It has fallen out of favor since insulin glargine and other long acting agents allow for few injections and more stable kinetics.

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On this episode of the Top 200 drugs podcast from Real Life Pharmacology, I cover medications 131-135 which include enoxaparin, methylphenidate, rosuvastatin, denosumab, and dabigatran.

Enoxaparin is an injectable anticoagulant that can cause heparin-induced thrombocytopenia.

Methylphenidate is a stimulant medication that can be used to treat ADHD. Cardiovascular adverse effects are possible.

Rosuvastatin inhibits HMG-CoA Reductase which helps lower LDL in the management of hypercholesterolemia.

Denosumab is a monoclonal antibody that is indicated for osteoporosis and may cause hypocalcemia.

Dabigatran was one of the first direct oral anticoagulants to be produced. It is dosed twice daily and has warnings about use in patients over the age of 75.

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In this episode of the Top 200 Drugs Podcast, we cover medications 126-130.

Trastuzumab is a monoclonal antibody that can be used for breast cancer that expresses the HER2 protein.

Atripla is an HIV medication that contains three separate medications that are beneficial in reducing viral load.

Rivaroxaban is an anticoagulant that may be commonly used in the management of stroke and deep vein thrombosis.

Fioricet is a combination of three medications. Butalbital, acetaminophen, and caffeine are the three ingredients in this medication.

Insulin detemir is a long-acting insulin analog that lowers blood sugar. This medication is used to target fasting blood sugars.

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On the top 200 drugs podcast, we cover 5 more medications. The medications covered on today’s episode include; omalizumab, nitroglycerin, apixaban, gabapentin, and etanercept.

Omalizumab is a monoclonal antibody used in moderate to severe asthma. It targets IgE-mediated asthma attacks and reactions. Anaphylaxis is a significant concern with the use of this medication.

Sublingual nitroglycerin is frequently used on an as needed basis for angina symptoms. I discuss major drug interactions and much more.

Apixaban is an anticoagulant used to prevent stroke in atrial fibrillation. It can also be used in DVT/PE treatment and prevention.

Gabapentin is classified as an antiepileptic agent but is most commonly used for neuropathic type pain.

Etanercept targets TNF alpha which plays an important role in autoimmune diseases such as rheumatoid arthritis.

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In this episode of the Top 200 Drugs Podcast, I cover glyburide, citalopram, olmesratan, carvedilol, and tiotropium.

Glyburide is a sulfonylurea that is well known to cause hypoglycemia and weight gain because it stimulates the pancreas to increase insulin release.

Citalopram is an SSRI most well known for its potential to increase the risk for QTc prolongation. It has a notorious drug interaction with omeprazole

Olmesartan is an ARB that can be used for hypertension. Hyperkalemia is an electrolyte imbalance that can be caused by its use.

Carvedilol is one of the few beta-blockers with significant alpha-blocking and beta-blocking activity. I discuss what this means in this Top 200 drugs podcast.

Tiotropium is an anticholinergic medication that can open the airway. It is most commonly used for COPD.

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Clindamycin is an antibiotic for infection. It inhibits protein synthesis by binding to the 50s ribosomal subunit and is well known to contribute to C. Diff. risk.

Acetaminophen is a common over-the-counter medication that relieves pain and fever. It does not have much benefit in reducing inflammation, however.

Ferrous sulfate is a supplement that can be useful in treating anemia. Dark stools and constipation are two common adverse effects.

Eletriptan is a medication used to abort migraine headaches. It has serotonin action. I discuss the potential for interactions with other serotonergic medications.

Methocarbamol is an older skeletal muscle relaxant that makes an appearance on the Beers list as it can cause sedation, confusion, and increase the risk of falls.

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Zoledronic acid is a bisphosphonate that can be used to manage hypercalcemia of malignancy and osteoporosis.

Glipizide is an anti-diabetes agent that is classified as a sulfonylurea. Weight gain and hypoglycemia and two big concerns with this agent.

Lactulose is classified as a laxative but is more commonly used to reduce ammonia levels in hepatic encephalopathy.

Rabeprazole is a PPI used to reduce gastric acid secretions and improve conditions such as GERD, peptic ulcer disease, and Barrett’s esophagus.

Methotrexate is classically grouped with oncology agents but is frequently used in autoimmune conditions like rheumatoid arthritis and Crohn’s disease.

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On this episode of the Real Life Pharmacology podcast, we cover medications 101-105 of the top 200 drugs

Atomoxetine is a norepinephrine reuptake inhibitor that is used in the management of attention deficit hyperactivity disorder.

Zolpidem is a medication that is used for insomnia. It has a very similar adverse effect profile to benzodiazepines.

Advair is a commonly used respiratory medication for asthma. It is a combination of a long-acting beta agonist and inhaled corticosteroid.

Levofloxacin is a quinolone antibiotic that has a boxed warning for neuropathy, tendon rupture, and CNS adverse effects.

Imipramine is a tricyclic antidepressant that is highly anticholinergic. Dry eyes, dry mouth, constipation, urinary retention, sedation, and memory impairment are potential adverse effects.

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We have finally reached 100 of the top 200 drugs podcasts!

On this episode, we tackle methadone. This is a complex opioid used for opioid use disorder and may also be used for pain.

Enalapril is an ACE inhibitor that is used for hypertension. Cough and hyperkalemia are two major adverse effects to remember.

Oseltamivir is a neuraminidase inhibitor. In patients with poor renal function, we need to make sure to adjust the dose accordingly.

Ropinirole is a dopamine agonist. This medication is primarily used for restless leg syndrome but is also indicated for Parkinson’s disease.

Penicillin VK is the original penicillin antibiotic. Common indications of this medication are strep throat, skin and soft tissue infections, and syphilis.

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