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Clopidogrel (Plavix) is an antiplatelet medication. You need to understand the pharmacokinetics of clopidogrel and how CYP2C19 affects this medication.

Doxycycline is a tetracycline antibiotic. Calcium, iron, and other metal cations can bind doxycycline and reduce the absorption of the medication.

Hyzaar is a combination of losartan and hydrochlorothiazide. Losartan is an ARB and hydrochlorothiazide is a thiazide diuretic.

Kytril (granisetron) is an antiemetic medication. It is from the same class of medication as the more commonly used ondansetron.

Restoril (temazepam) is a benzodiazepine. It is primarily used to treat insomnia as it has a much shorter half-life than many of the other benzodiazepines.

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On this episode of the Real Life Pharmacology Podcast, we will cover medications 186-190 on the Top 200 Drugs List.

The medications included in the podcast episode are Sonata, Zebata, Zovirax, Coumadin, and Luvox.

Sonata (ezopiclone) is a Z-drug used for insomnia. It has many similar effects to benzodiazepines and a similar mechanism of action.

Zebeta (bisoprolol) is a beta-blocker used for the treatment of hypertension, atrial fibrillation, and heart failure amongst other indication.

Zovirax (acyclovir) is an antiviral medication used to treat various viral infection. It needs to be dosed numerous times throughout the day which is a downside to use.

Coumadin (warfarin) is an anticoagulant. It is most well known for its need to have INRs drawn to assess drug levels.

Luvox (fluvoxamine) is an SSRI antidepressant. It is well known for its ability to cause drug interaction and is often not a first line agent because of this reason.

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On this Real Life Pharmacology Podcast episode, we cover medications 181-185.

Proscar is the brand name for finasteride. This medication can be helpful in shrinking the size of the prostate but it does typically take a while to work (months).

Sinemet is a combination of carbidopa and levodopa. Levodopa is converted in the central nervous system to dopamine to help alleviate a shortage of dopamine in the brain.

Risedronate is a bisphosphonate medication that can be used in the treatment of osteoporosis.

Albuterol (Ventolin) is a short-acting beta-agonist that is used to relieve symptoms of acute respiratory distress most often associated with an asthma exacerbation.

Tramadol is classified as an opioid analgesic. It also has activity similar to SNRIs as it has the ability to increase serotonin and norepinephrine in the brain.

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Prednisolone is a corticosteroid that is often used in pediatrics. Hyperglycemia, insomnia, and GI upset are relatively common adverse effects.

Ibuprofen is a commonly used OTC pain reliever. It is classified as an NSAID and can increase GI bleed risk and exacerbate heart failure.

Aceon is the brand name for perindopril. ACE inhibitors are well known to cause drug induced cough and will cause hyperkalemia.

Trazodone is classified as an antidepressant but is frequently used to treat insomnia because of its sedative properties.

Pioglitazone is an oral anti-diabetes medication that should be avoided in patients with heart failure.

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On this episode of the Top 200 drugs podcast, we are going to cover these 5 medications: Cyclosporine, insulin glargine, tadalafil, amitriptyline, and gemfibrozil.

Cyclosporine is a calcineurin inhibitor that suppresses the immune system. This is useful in patients who have had an organ transplant.

Insulin glargine is a long-acting insulin product that can be used in type 1 and type 2 diabetes. I discuss adverse effects, dosing, and much more.

Tadalafil is a PDE-5 inhibitor that can be used to treat sexual dysfunction. The nitrate drug interaction is one of the most highly tested drug interactions in school.

Amitriptyline is a TCA. It is highly anticholinergic and because of this is not a great medication to utilize in elderly patients.

Gemfibrozil is primarily used to lower triglyceride levels. This medication can significantly increase the risk for rhabdomyolysis in patients taking statin medications.

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On this episode of the Top 200 Drugs podcast from Real Life Pharmacology, we cover Percocet, Epogen, quetiapine, glimepiride, and tirzepatide. These are drugs 166-170.

Percocet is a combination analgesic. It contains acetaminophen and oxycodone. Pay attention to acetaminophen intake from all sources when patients are on this medication.

Epogen (epoetin alfa) stimulates the production of red blood cells. This medication can be useful in treating anemia.

Quetiapine (Seroquel) is an antipsychotic. It is often used in patients with hallucinations and delusions associated with Parkinson’s disease because it has a lower potential to block dopamine receptors compared to other antipsychotics.

Glimepiride is a sulfonylurea. This medication stimulates the release of insulin which can help lower blood sugars in diabetes.

Tirzepatide (Mounjaro) is a combination GIP and GLP-1 receptor agonist that can be used for weight loss and the treatment of diabetes.

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On this podcast episode of the top 200 drugs, I’m covering liraglutide, folic acid, clotrimazole, empagliflozin, and semaglutide.

Liraglutide is a GLP-1 agonist that can be used for weight loss as well as diabetes. The most common adverse effect of this medication is nausea.

Folic acid is a commonly used supplement in pregnancy as well as in those patients taking methotrexate. Deficiency of folic acid can lead to anemia.

Clotrimazole is an antifungal agent. It is mostly used for topical purposes such as athlete’s foot and vaginal yeast infections.

Empagliflozin was originally developed as a diabetes medication but can be helpful in patients with heart failure and CKD. I discuss this in greater detail in the podcast.

Semaglutide is another GLP-1 agonist that is used for diabetes care as well as weight loss. The formulation used for diabetes is Ozempic while the weight loss product is Wegovy.

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Welcome back to the Real Life Pharmacology podcast! We are on the home stretch of the top 200 medications. This is meant to be a quicker refresher of some of the most important drugs you’ll come across in practice. Please be sure to go search the archives at RealLifePharmacology.com if you are looking for more information on one specific medication. We have over 300 individual episodes on specific drugs!

On this episode of the Top 200 medications, we’ve covered the medications below.

Niaspan (niacin) is vitamin B3 and may be used in patients who fail other therapies for triglyceride management.

Uroxatral (alfuzosin) is a selective alpha-blocker that can be helpful in relieving urinary retention symptoms in BPH.

Biaxin (clarithromycin) is a macrolide antibiotic that is notorious for many drug interactions because it inhibits CYP3A4.

Zomig (zolmitriptan) is a “triptan” medication that can be used for the acute relief of migraine headaches.

Invokana (canagliflozin) was one of the first SGLT2 inhibitors invented that can be used to lower blood sugar in type 2 diabetes.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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On this episode of the Top 200 Drugs Podcast, I cover medications 151-155. This podcast includes; cefuroxime, ketoconazole, pregabalin, esomeprazole, and ipratropium/albuterol.

Cefuroxime is a 2nd generation cephalosporin that has a very similar bacterial coverage profile to amoxicillin. It has significant gram positive coverage.

Ketoconazole is an azole antifungal medication. It is well known for causing hepatotoxicity as well as interactions via CYP3A4.

Pregabalin has a lot of similarities with gabapentin. It can be used fo various pain syndromes such as neuropathy and fibromyalgia.

Esomeprazole is a PPI and has a similar profile to omeprazole. It inhibits CYP2C19 and has a few notable interactions that I cover in this episode.

Ipratropium and albuterol is a combination of a short acting anticholinergic and short acting beta agonist.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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On this episode of the Top 200 Drugs Podcast, I cover medications 146-150. This podcast includes; sevelamer, dalteparin, sertraline, clonazepam, and irbesartan.

Sevelamer is a phosphate binder that is used to treat hyperphosphatemia in patients with chronic kidney disease.

Dalteparin is a low molecular weight heparin product that is used to prevent and treat blood clots.

Sertraline is a commonly used SSRI that can be helpful in managing depression and anxiety.

Clonazepam is a benzodiazepine that can be used for acute relief of anxiety. Sedation, confusion, and fall risk are potential adverse effects.

Irbesartan is an ARB that can be used for hypertension. Hyperkalemia and angioedema are two adverse effects to be aware of.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!