Sci Guys

134: The Science of Gene Editing & Treating Blindness

Listen Later
For the first time ever we’ve used CRISPR  to edit someone’s genes INSIDE THEIR BODY! So far we’ve been able to reverse some effects of rare genetic eye disease that results in blindness, and this is only the beginning!

You can WATCH the podcast over on our YouTube channel:
http://youtube.com/SciGuys

Help keep the show running by supporting us on Patreon!
http://patreon.com/sciguys

If you'd like to see more of us, follow our socials!

Facebook
http://facebook.com/SciGuysPod

Twitter
http://twitter.com/SciGuysPod

Instagram
http://instagram.com/SciGuysPod

Follow the SCI GUYS
@notcorry / @jampkin / @lukecutforth

References & Further Reading

  1. https://medlineplus.gov/genetics/condition/leber-congenital-amaurosis/
  2. https://rarediseases.info.nih.gov/diseases/634/leber-congenital-amaurosis
  3. https://luxturna.com

    4. Gene Therapy
    1. https://www.nature.com/articles/d41586-018-06195-6
    2. https://www.nature.com/articles/s41587-020-0493-4
    3. https://www.nature.com/articles/s41573-019-0012-9

      4. The EDIT-101 Trial
      1. https://clinicaltrials.gov/ct2/show/study/NCT03872479
      2. https://www.nature.com/articles/s41591-018-0327-9
      3. https://text.npr.org/2021/09/29/1040879179/vision-loss-crispr-treatment
      4. https://www.nature.com/articles/d41586-020-00655-8https://www.nature.com/articles/d41586-020-00655-8
      5. https://jamanetwork.com/journals/jama/fullarticle/2764428https://jamanetwork.com/journals/jama/fullarticle/2764428
        6. ...more
        View all episodesView all episodes
        Download on the App Store
        Sci GuysBy The Sci Guys
        • 4.9
        • 4.9
        • 4.9
        • 4.9
        • 4.9

        4.9

        293 ratings

        More shows like Sci Guys

        View all
        Dear Hank & John by Complexly

        Dear Hank & John

        7,718 Listeners

        No Such Thing As A Fish by No Such Thing As A Fish

        No Such Thing As A Fish

        4,869 Listeners

        Escape This Podcast by Escape This Podcast

        Escape This Podcast

        333 Listeners

        Ologies with Alie Ward by Alie Ward

        Ologies with Alie Ward

        24,310 Listeners

        Gender Reveal by Tuck Woodstock

        Gender Reveal

        1,253 Listeners

        SciShow Tangents by Complexly

        SciShow Tangents

        1,509 Listeners

        Sad Boyz by Jarvis Johnson & Jordan Adika

        Sad Boyz

        1,213 Listeners

        I Could Murder A Podcast by I Could Murder A Podcast

        I Could Murder A Podcast

        123 Listeners

        Taskmaster The Podcast by Avalon

        Taskmaster The Podcast

        742 Listeners

        Maintenance Phase by Aubrey Gordon & Michael Hobbes

        Maintenance Phase

        16,474 Listeners

        Let's Learn Everything! by Maximum Fun

        Let's Learn Everything!

        421 Listeners

        Lateral with Tom Scott by Tom Scott and David Bodycombe

        Lateral with Tom Scott

        451 Listeners

        Chosen Family by Chosen Family & Studio71

        Chosen Family

        904 Listeners

        A Bit Fruity with Matt Bernstein by Matt Bernstein

        A Bit Fruity with Matt Bernstein

        2,405 Listeners

        The Rest Is Entertainment by Goalhanger

        The Rest Is Entertainment

        989 Listeners