We reach the Big 1-5-0, in which I discuss the venerable history of mRNA vaccines, from the 1960s to the present, from a chemical point of view. We hear of transferring mRNA into cells, then transferring anti-viral mRNA into cells. There are a variety of mRNA vaccines under study--not merely COVID, but flu, RSV, and even cancer treatments. Patreon supporters may download a supplemental sheet with diagrams of some of the biochemical systems I describe.

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