Sci Guys

153: Xenotransplants: The Man With a Pig Heart


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Human organs are in short supply - but this year scientists decided to genetically modify a pig heart to save the life of a man with terminal heart disease. This xentoransplant is brand new science & had never been done before. This week we go over the crazy experiments and mind-blowing science that led to this medical marvel.

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References & Further Reading

Xenotransplantation
https://archive.bio.org/articles/xenotransplantation-benefits-and-risks-special-organ-transplantation
https://www.omixon.com/brief-history-xenotransplantation/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684730/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246856/
https://www.who.int/ethics/en/ETH_Nuffiled_xenotransplantation.pdf
https://www.frontiersin.org/articles/10.3389/fimmu.2019.03060/full
https://www.fda.gov/vaccines-blood-biologics/xenotransplantation
https://www.groomers-online.com/professional-c1/scissors-c22/left-handed-scissors-c265/groomers-elite-45-straight-left-handed-bull-nosed-scissors-p755
https://pubmed.ncbi.nlm.nih.gov/34697231/

Organ Donation & Transplants
https://www.organdonation.nhs.uk/helping-you-to-decide/about-organ-donation/statistics-about-organ-donation/
https://www.organdonation.nhs.uk/helping-you-to-decide/about-organ-donation/living-donation/
https://www.nhsbt.nhs.uk/what-we-do/transplantation-services/organ-donation-and-transplantation/

First Pig Heart Transplant
https://www.economist.com/science-and-technology/2022/01/15/the-science-behind-the-first-successful-pig-to-human-heart-transplant
https://www.bbc.co.uk/news/world-us-canada-59944889.amp
https://www.nature.com/articles/d41586-022-00111-9
https://secure.jbs.elsevierhealth.com/action/consumeSsoCookie?redirectUri=https%3A%2F%2Fwww.thelancet.com%2Faction%2FconsumeSharedSessionAction%3FJSESSIONID%3DaaaBetSmryb39fIGYw37x%26MAID%3DcerwNnXJRoDD37sdGKDXfw%253D%253D%26SERVER%3DWZ6myaEXBLFD8VbcQEfOcg%253D%253D%26I2KBRCK%3D1%26ORIGIN%3D695817921%26RD%3DRD%26exp%3DTEn4cY9Dbt214rWTophWGQ%25253D%25253D&code=null&acw=Secure;SameSite=None&utt=
https://amp.theguardian.com/science/2022/feb/03/german-researchers-to-breed-pigs-for-human-heart-transplants
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