The Curbsiders Internal Medicine Podcast

#253 COVID-19 Vaccines with Dr Monica Gandhi

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Answer all your burning questions (and your patients’ burning questions) about the different COVID-19 vaccines currently authorized in the US. Infectious diseases / HIV expert, Dr Monica Gandhi @MonicaGandhi9 (UCSF) joins us to cover: the Pfizer-BioNTech and Moderna novel mRNA vaccine mechanisms, trial data, and practicalities of who should receive them.  We discuss data around the Oxford-AstraZeneca adenovirus vaccine, which is authorized in the UK and India, and may be available in the US later this year.  Feel confident recommending COVID-19 vaccines to your patients!

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Credits

  • Written and Produced by: Molly Heublein, MD
  • Cover Art: Chris Chiu, MD, FACP, FAAP
  • Infographic: Tima Karginov
  • Hosts: Chris Chiu, MD, FACP, FAAP; Molly Heublein, MD; Paul Williams, MD, FACP
  • Editor: Emi Okamoto MD (written materials); Clair Morgan of Nodderly.com (audio)
  • Guest: Monica Gandhi, MD, MPH



    • Sponsor: Panacea Financial 
    This episode is supported by Panacea Financial, digital banking built for doctors, by doctors. At Panacea Financial you can have your own free personal banker and a support team that works around the clock- just like you do. Open your free checking account today at panaceafinancial.com

    Panacea Financial, a Division of Sonabank, Member FDIC



    Sponsor: VCU Health CE
    The Curbsiders are partnering with VCU Health Continuing Education to offer FREE continuing education credits for physicians and other healthcare professionals. Visit curbsiders.vcuhealth.org.



    Time Stamps

    • Intro, disclaimer, guest bio - 00:00
    •  Guest one-liner, book recommendation - 3:40
    • Authorized vaccines in the US - 8:30
    • AstraZeneca vaccine mechanism- 9:26
    • mRNA vaccine mechanism - 10:30
    • Vaccine distribution issues (cold chain) - 16:05
    • mRNA safety - 18:24
    • mRNA vaccine efficacy/data from phase 3 trials - 19:40
    • How did we get this so quickly - 23:40
    • Vaccine impact on asymptomatic infection - 26:18
    • AstraZeneca trials - 28:20
    • Pregnancy - 35:10
    • Anaphylaxis - 37:10
    • Prior COVID-19 infection - 39:07
    • Side effects - 42:05
    • Pediatric patients - 45:12
    • Phases of role outs in the US -46:50
    • Herd immunity - 48:16
    • Thoughts of how to make this happen - 52:45
    • Preexisting conditions - 53:40
    • How long will immunity last - 57:15
    • Mutant strains - 58:25
    • Future of mRNA vaccines - 1:00:30
    • Take home points and Outro - 1:02:12
      • ...more
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