January 6, 2016 You likely won’t hear about the MTHFR genetic mutation in your doctor’s office, but 60% of the population has this condition. If you have the MTHFR mutation, it means that (among other things) your body cannot convert folic acid into folate that you need for a healthy baby and your own cell replication. Listen in as I speak with expert, Angela Heap about: what is MTHFR what tests can determine whether you have the MTHFR mutation the difference between folic acid and folate how MTHFR affects women trying to conceive and those that have suffered multiple miscarriages what supplements for folates and B12 you should take if you have the MTHFR mutation.