DNA Today: A Genetics Podcast

#335 Neanderthals, Denisovans, and Us: How DNA Reveals Evolution


Listen Later

This conversation is a follow-up to Episode #326: How DNA Solves Crimes – The Forensic Science Behind True Crime, where we explored the role of DNA in forensic investigations including the infamous O.J. Simpson case. Dr. Henry Erlich returns to the show to talk about human ancestry and evolution. 

Dr. Henry Erlich has authored over 450 publications and spent decades applying DNA analysis to criminal investigations, missing persons cases, and ancestry research. His work has helped us trace human origins, understand genetic diversity, and uncover how DNA links us to Neanderthals and Denisovans. His lab performed the first DNA case in the US and, in 1988, the first DNA exoneration. Erlich was the Director of the Department of Human Genetics and Vice-President of Discovery Research for Roche Molecular Systems, Inc until 2013. He is currently a Senior Scientist at Benioff Children’s Hospital Oakland Research Institute. 

Topics Covered in This Episode:
  • How PCR revolutionized genetic research and our understanding of evolution
  • What genetic diversity within African populations tells us about human origins
  • Debunking myths about Mitochondrial Eve and human ancestry
  • The genetic connections between humans, Neanderthals, and Denisovans
  • How ancient DNA from medieval bones reshapes what we know about genetic bottlenecks
  • Insights from the Pangenome Project and its potential to improve our understanding of genetic variation
  • Relevant Episodes: 
    • #326: How DNA Solves Crimes – The Forensic Science Behind True Crime (First Episode with Dr. Henry Erlich)
    • #216 African American Ancestry with Nicka Smith
    • #117 Dr. Janina Jeff on African Genomes
    • #251 Diversifying Genetic Research with 23andMe (Explores African American Sequencing Project)
    • #182 Dr. Eric Green on the Complete Human Genome Project and Pan Genome Project
    • Resources and Links:
      • Read Genetic Reconstruction of the Past by Dr. Henry Erlich
      • Explore the National DNA Index System (NDIS) and CODIS
      • The Innocence Project: Fighting wrongful convictions with DNA evidence
      • GEDmatch and its role in forensic investigations
      • Get ready, genetic nerds—another brand-new episode of DNA Today drops next Friday! You can always count on us to deliver fresh content every Friday. 

        While you wait, why not dive into our library of over 300 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen—just search “DNA Today.”

        Prefer watching? We’ve got you covered! For the past four years, we’ve been recording episodes with video, including some filmed at the iconic NBC Universal Stamford Studios. Check them out on our YouTube channel

        DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Video Lead is Amanda Andreoli. Our Social Media Lead is Kajal Patel. Our Outreach Intern is Liv Davidson. And our logo Graphic Designer is Ashlyn Enokian, MS, CGC. 

        ...more
        View all episodesView all episodes
        Download on the App Store

        DNA Today: A Genetics PodcastBy Kira Dineen

        • 4.7
        • 4.7
        • 4.7
        • 4.7
        • 4.7

        4.7

        153 ratings


        More shows like DNA Today: A Genetics Podcast

        View all
        Hidden Brain by Hidden Brain, Shankar Vedantam

        Hidden Brain

        43,767 Listeners

        This Week in Virology by Vincent Racaniello

        This Week in Virology

        2,054 Listeners

        Nature Podcast by Springer Nature Limited

        Nature Podcast

        761 Listeners

        Big Picture Science by Big Picture Science

        Big Picture Science

        941 Listeners

        This Week in Microbiology by Vincent Racaniello

        This Week in Microbiology

        518 Listeners

        Discovery by BBC World Service

        Discovery

        961 Listeners

        BBC Inside Science by BBC Radio 4

        BBC Inside Science

        436 Listeners

        Science Weekly by The Guardian

        Science Weekly

        417 Listeners

        Science Magazine Podcast by Science Magazine

        Science Magazine Podcast

        824 Listeners

        Science Friday by Science Friday and WNYC Studios

        Science Friday

        6,352 Listeners

        TED Health by TED

        TED Health

        1,427 Listeners

        Science In Action by BBC World Service

        Science In Action

        354 Listeners

        Unexpected Elements by BBC World Service

        Unexpected Elements

        352 Listeners

        The world, the universe and us by New Scientist

        The world, the universe and us

        111 Listeners

        NEJM AI Grand Rounds by NEJM Group

        NEJM AI Grand Rounds

        59 Listeners