The Curbsiders Internal Medicine Podcast

#342 Checkpoint Inhibitors: The power, and adverse effects, of immunotherapy (ACP 2022)

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With great power comes great immunogenicity.  Learn about the ins and outs of immunotherapy–its indications, its power, and its adverse effects–in this episode with Dr. Christian Cable, hematologist/oncologist and medical educator extraordinaire.  We learn a riveting history of immunotherapy and about how checkpoint inhibitors work, as well as the best practices for identifying downstream effects of checkpoint inhibitors and their immune system activation (it’s all about the -Itis!).

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Show Segments

  • Intro
  • What is Immunotherapy?
  • A History Lesson
  • Immune Checkpoint Inhibitors (ICIs) 
  • Immune Related Adverse Events (irAEs) 
  • Endocrine complications of checkpoint inhibitors
  • Rheumatologic complications of checkpoint inhibitors 
  • Considerations before starting checkpoint inhibitors (and what labs to check) 
  • Diagnosing and Managing irAEs 
  • Common post-irAE questions 
  • New Kids on the Block: CAR-T 
  • Take Home Points 

    • Credits

    • Written and Produced by: Nora Taranto MD
    • Hosted by: Molly Heublein MD; Nora Taranto MD; Paul Williams MD, FACP  
    • Guests: Christian Cable MD 
    • Show Notes: Nora Taranto MD 
    • Cover Art: Andrea Perdigão
    • Infographics: Andrea Perdigão
    • Reviewer: Emi Okamoto MD, FACP 
    • Production team: Pod Paste
      • Sponsor: Southern California Permanente Medical Group
      Learn more or apply at scpmgphysiciancareers.com

      Sponsor: Locumstory
      Visit locumstory.com to learn more about locums.

      Full transcript HERE

      The Curbsiders are partnering with VCU Health Continuing Education to offer FREE continuing education credits for physicians and other healthcare professionals. Visit curbsiders.vcuhealth.org and search for this episode to claim credit
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