The Curbsiders Internal Medicine Podcast

#399 Wisely Ordering Autoantibodies - ACP IM2023


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The ANA, anti-CCP, RF, and beyond!

We all have ‘rheum’ to grow when it comes to making sense of autoantibodies and common markers. We talk through the nuances with rheumatologist Dr. Matthew B. Carroll (biography here!). Our interview covers physical exam tips for inflammatory arthritis, basic interpretation of rheumatologic testing, and what to do with the dreaded ‘vaguely positive’ speckled ANA!

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Show Segments
  • Intro
  • Case 1
  • History clues
  • Physical exam pearls; what does synovitis look like?
  • Interpreting mixed labs
  • Rheumatoid Factor tips
  • Role for imaging
  • Importance of early diagnosis
  • New testing modalities
  • Case 2
  • Oh no– a vaguely positive ANA!
  • ANA testing basics
  • Outro
  • Credits
    • Showrunners, Hosts, Producers and Writers: Matthew Watto MD, FACP; Paul Williams MD, FACP   
    • Show Notes, Infographic, Cover Art: Beth Garbitelli MD
    • Reviewer: Emi Okamoto MD 
    • Technical Production: PodPaste
    • Guest: Matthew B. Carroll MD

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