This week, Jon and Charlene are six weeks into their Ozempic journey and getting real about the emotional ups and downs of plateauing, the weird “stoned” side effect, and what it actually means to feel full on this medication. Plus, Jon dives deep into the world of GLP-1 medications and what’s coming next—from Ozempic and Wegovy to Mounjaro and the mysterious “Retatrutide.”

💉 Is Ozempic really the best option?

📉 How much weight are they losing week to week?

🌀 That strange semi-stoned side effect—Charlene finally feels it too.

🧪 Plus: a breakdown of the current and future weight-loss drugs shaking up the market.

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Timestamps & Highlights

⏳ [00:00] – Week 6 begins: Moving up to 0.5mg

⏳ [01:00] – “Wait… am I stoned?” Charlene experiences a new Ozempic side effect

⏳ [03:30] – Feeling overfull, even with small meals—managing food + hydration

⏳ [04:30] – Rehydration & electrolytes: Are you accidentally flushing out too much?

⏳ [05:35] – Weekly weigh-in: Jon hits 93.6kg, Charlene’s down another 800g

⏳ [06:30] – Half a kilo a week = success: The power of slow, steady progress

⏳ [08:40] – 🧬 Ozempic Johnsplains: A full breakdown of semaglutide, tirzepatide, and what’s next in weight-loss medication

⏳ [12:30] – Why Charlene’s staying at 0.5mg (and why she dreads nausea!)

⏳ [13:30] – Goals for Week 7: Gym motivation, protein intake, and winter creeping in

⏳ [15:30] – When exercise becomes part of your identity—and the temptation of red wine season

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