GLP-1 Hub: Support, Community, and Weight Loss

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A daily GLP-1 pill sounds like an easy way to maintain your weight loss, but what happens when it doesn't work like the shot did? Registered dietitian Whitney Black, who lives with type 1 diabetes, shares what happened when she switched from Zepbound to Foundayo (orforglipron) for maintenance, and why she went back after two months. You'll hear how her fullness cues, blood sugar, and insulin needs changed, and what she tells clients about weight regain. The surprise wasn't the food noise. It was a different signal that quietly went missing. This is one person's experience, not a verdict on how the pill will work for everyone.

IN THIS EPISODE

- Whitney's path to Zepbound with type 1 diabetes, Hashimoto's, and PCOS
- Why hunger and fullness dysregulation is biology, not a personal failing
- Where GLP-1s stand for type 1 diabetes, and why insulin changes need your care team
- What Foundayo is (an oral GLP-1 from Eli Lilly, not tirzepatide) and how its dosing differs
- How her fullness cues and blood sugar changed on Foundayo, and the roughly 15 pounds she regained in two months
- Cost versus effectiveness when choosing a maintenance option
- Switching back to Zepbound and slowly titrating up again
- Practical and mental strategies when weight comes back after a break in medication

ABOUT THE GUEST

Whitney Black, MBA, MS, RD, LD, LMNT, is a registered dietitian specializing in weight management and practical nutrition for individuals using GLP-1 medications. Through her private practice and online education, she helps people navigate nutrition, weight management, and metabolic health with an evidence-based, realistic approach. Whitney also brings her own lived experience with weight management and GLP-1 medications to her work, allowing her to connect clinical expertise with the real-life experience of navigating these treatments. She is also the author of an upcoming GLP-1-focused cookbook with Fair Winds Press.

CONNECT WITH WHITNEY BLACK

Instagram: https://www.instagram.com/whitney.the.dietitian/
Work with Whitney (Nourish): https://signup.nourish.com/providers/whitney-black

SPONSORS

This episode is brought to you by Timeline. When you buy a one-month supply of Mitopure Gummies, you'll get a free Discovery Size Mitopure Firming Serum, an $85 value. Go to https://www.timeline.com/glp1bundle to claim yours.

This episode is also brought to you by Tyde Wellness, the GLP-1 provider Ana uses, with nutrition guidance built for GLP-1s, independent licensed providers, and a care team that answers when something comes up. Go to https://tydewellness.com/GLP1Hub and use code GLP1Hub50 for $50 off your first month.

CHAPTERS

00:00 Preview: why the pill appealed to her
00:21 Introduction
01:04 Welcome, Whitney Black
02:17 Life before GLP-1s with type 1 diabetes, Hashimoto's, and PCOS
04:54 Starting Zepbound as a dietitian
06:53 Fullness cues: it's biology, not willpower
08:38 GLP-1s and type 1 diabetes today
12:29 Maintenance, dosing, and why she tried Foundayo
12:57 What Foundayo is (and isn't)
14:29 Sponsor: Timeline
15:23 Foundayo dosing and the first weeks
16:44 Losing the fullness signal
18:53 Rising blood sugar and insulin resistance
19:26 Cost versus effectiveness
21:40 Back on Zepbound
24:00 Advice when weight comes back after a break
26:14 Sponsor: Tyde Wellness
27:14 Why it's not just an appetite suppressant
30:08 Where to find Whitney
31:26 Closing

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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If you're taking a GLP-1, headlines about sudden vision loss can leave you wondering whether the medication helping you lose weight is putting your eyesight at risk. Ana Reisdorf talks with Dr. Luke Sorrell about NAION, a rare optic nerve condition, and the semaglutide research behind those headlines. You'll learn how to put "double the risk" into perspective, what questions to bring to your doctor, and why your health history matters to the conversation.

**IN THIS EPISODE**

- What NAION is and how it can affect vision
- What semaglutide studies suggest, and the limits of observational research
- Why relative risk and absolute risk tell different parts of the story
- How diabetes, sleep apnea, cardiovascular health, and optic nerve anatomy fit into the discussion
- Blood pressure changes, dehydration, and rapid blood sugar changes as possible contributing factors
- Questions to ask your prescriber and eye care professional about your individual risk
- What remains uncertain about tirzepatide and other GLP-1 medications
- Weighing potential eye risks alongside the benefits of GLP-1 treatment

**ABOUT THE GUEST**

Dr. Luke Sorrell is a board-certified internal medicine physician, Fellow of the American College of Physicians, and founder of Sorrell MD, a concierge longevity and precision telemedicine practice based in Dallas-Fort Worth, Texas, serving patients across the U.S. He trained at UT Houston McGovern Medical School and completed his residency at Baylor University Medical Center in Dallas. His career has spanned hospital medicine, primary care, and longevity medicine. Today, he works with high-performing and health-conscious individuals across the country, using tools like cardiac CT angiography, VO2 max and metabolic testing, DEXA, genomics, and advanced hormone and lipid panels to identify health risks earlier. He also advises health tech companies building the next generation of care.

**CONNECT WITH DR. LUKE SORRELL**

Website: https://www.sorrell-md.com
LinkedIn: https://www.linkedin.com/in/luke-sorrell-md/
Instagram: https://www.instagram.com/sorrellmd/
Facebook: https://www.facebook.com/SorrellMD
Substack: https://substack.com/@sorrellmd

**SPONSOR**

Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
https://tydewellness.com/GLP1Hub

**CHAPTERS**

00:00 GLP-1s and NAION: The "double risk" headline
01:42 Meet Dr. Luke Sorrell
02:52 What is NAION?
05:10 How rare is NAION?
06:13 Diabetes, sleep apnea, and other risk factors
07:50 What the studies show and their limitations
10:49 Relative risk versus absolute risk
11:58 Sponsor: Tyde Wellness
13:22 Semaglutide, tirzepatide, and unanswered questions
14:22 Possible mechanisms: Blood pressure, oxygen, and hydration
19:05 Eye exams, optic nerve anatomy, and rapid A1C changes
22:15 Questions to bring to your doctor
24:54 Ana's Plateau Breakthrough Playbook
26:15 Staying grounded when health headlines spread
27:20 Retatrutide and the future of GLP-1 treatment
29:31 Connect with Dr. Sorrell
30:01 Weighing eye concerns against cardiovascular benefits
31:25 Closing thoughts and podcast reviews

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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If breast cancer runs in your family, you may be wondering whether you're getting the right screening and what else you can do to lower your risk. Ana Reisdorf talks with Dr. Anne Peled about how GLP-1s may shift the balance, what everyday habits you should build, and why weight can become harder to manage during and after treatment. You'll learn which questions to bring to your care team, how to protect your nutrition, and what emerging GLP-1 research still hasn't answered.

**IN THIS EPISODE**

- How family history and breast density can shape your screening conversation
- Exercise, alcohol, and food choices in the discussion about lowering breast cancer risk
- Why weight, inflammation, and cancer risk are more complicated than a single cause
- What early GLP-1 research suggests, and why prevention questions remain unanswered
- Why hormone-blocking medications and other cancer treatments can affect weight
- Protecting protein and nutrient intake while coordinating weight management with cancer care
- Personalized treatment, emerging research, and advocating for yourself

**ABOUT THE GUEST**

Dr. Anne Peled is a breast cancer and reconstructive surgeon in San Francisco and a two-time breast cancer survivor. She earned her medical degree at Harvard Medical School and completed plastic and reconstructive surgery training and a breast surgical oncology fellowship at UCSF. She is co-director of the Breast Care Center of Excellence at Sutter Health California Pacific Medical Center. Her work focuses on improving breast surgery and reconstruction outcomes, and she brings both a surgeon's and a patient's perspective to care.

**CONNECT WITH DR. ANNE PELED**

Website: https://www.annepeledmd.com
Instagram: https://www.instagram.com/drannepeled/

**SPONSOR**

Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
https://tydewellness.com/GLP1Hub

**CHAPTERS**

00:00 Body fat, estrogen, and breast cancer risk
00:24 Ana's personal connection and the questions this episode explores
01:33 Meet Dr. Anne Peled
03:29 Early detection, family history, and breast density
05:59 Mammograms and questions about additional scans
07:33 Exercise, alcohol, and nutrition
10:05 Weight, inflammation, and emerging GLP-1 research
11:18 GLP-1s for prevention: What we still don't know
13:39 Sponsor: Tyde Wellness
15:05 GLP-1 cancer concerns and unanswered questions
16:30 Why breast cancer treatment can affect weight
18:58 Discussing GLP-1 treatment with your care team
20:12 Protecting nutrition during cancer treatment
22:53 Survivorship and personalized treatment
25:12 Emerging microbiome research
26:44 Beyond the Shot guide
27:46 Genetics and the future of personalized screening
31:03 Self-advocacy, second opinions, and everyday movement
32:46 Connect with Dr. Peled

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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How are GLP-1 type medications and weight control changing the landscape of heart health? If you're using a GLP-1 for weight or blood sugar, which habits and risk factors still deserve attention? Ana Reisdorf talks with Dr. Melanie Icard about stress, sleep, muscle, food choices, and questions to bring to your healthcare team when heart disease runs in the family.

Dr. Icard shares how her experience with prediabetes shaped her practice and why she asks patients, "What are you doing to relax?" Ana brings the GLP-1 user's perspective: how to eat well with a smaller appetite and make strength work realistic when life is already full. They also discuss what Ana's family history has prompted her to ask about lab markers and heart imaging.

**IN THIS EPISODE**

- Why stress and sleep belong in a conversation about heart and metabolic health
- What it can look like to make room for real rest during a busy week
- How strength work and everyday movement fit into GLP-1 weight loss
- Choosing nourishing meals when your appetite is smaller
- Questions to ask your clinician about family history, lab markers, and heart imaging
- Building habits you can keep up as your health goals change

**ABOUT THE GUEST**

Dr. Melanie Icard, NMD, is a naturopathic and regenerative medicine physician with 24 years of clinical experience, including 11 years in hospital medicine. She leads Dr. Mel Holistic, a cardiovascular and metabolic medicine practice in Scottsdale and Sedona, Arizona, with a national virtual practice. Her Biohacked Heart Blueprint™ examines how chronic stress and HPA axis dysregulation (changes in the body's stress response) may relate to cardiovascular and metabolic health. She teaches the framework to medical professionals nationally.

**CONNECT WITH DR. MELANIE ICARD**

Website: https://www.drmelanieicard.com/
Instagram: https://www.instagram.com/drmelholistic/
YouTube: https://www.youtube.com/@Itsdrmel

**SPONSORS**

Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
https://tydewellness.com/GLP1Hub

**CHAPTERS**

00:00 What are you doing to relax?
00:18 Ana's family history and heart health beyond the scale
01:11 Meet Dr. Melanie Icard
06:23 Family history, calcium scoring, and prevention
07:09 Stress and sleep in the heart health conversation
08:44 Heart imaging and risk questions
12:58 Finding time to truly relax
15:42 Sponsor: Tyde Wellness
17:19 Stress, blood sugar, and GLP-1 goals
20:41 Meal habits and nutrient dense choices
23:54 Lab markers, imaging, and family risk
26:53 GLP-1s and preserving muscle
28:09 Making relaxation realistic
29:23 Beyond the Shot guide
30:24 Workload, boundaries, and healthy habits
32:10 Who Dr. Icard works with
33:42 Connect with Dr. Icard

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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If you're taking a GLP-1, you've probably heard plenty about protein and strength training. Where does creatine fit, and what does it mean if the scale rises after you start taking it? Ana Reisdorf talks with Kristin Kirkpatrick about muscle health, the practical choices involved in taking creatine, and what the research can and cannot yet tell us about benefits beyond the gym.

Kristin explains how creatine works alongside resistance training, why a loading phase may not be necessary, and what to consider when choosing a form. She and Ana also discuss bloating, water retention, early research on brain health, and whether you can build muscle after starting a GLP-1.

**IN THIS EPISODE**

- What creatine does in the body and why it comes up in the muscle-health conversation
- How creatine, protein, and resistance training fit together during GLP-1 weight loss
- What emerging research suggests about brain health and what it does not establish
- Creatine monohydrate, HCl, powders, and gummies: questions to consider when choosing a product
- Loading phases, dose, and timing, and why individual needs vary
- Water retention, bloating, and why a change on the scale may not mean fat gain
- Building strength and muscle after starting a GLP-1

**ABOUT THE GUEST**

Kristin Kirkpatrick, MS, RD, is a registered dietitian at Cleveland Clinic and president of KAK Consulting, LLC. She has worked in nutrition and integrative care for more than 20 years, contributes to TODAY.com, and co-authored Skinny Liver and Regenerative Health with gastroenterologist Ibrahim Hanouneh, MD.


**CONNECT WITH KRISTIN**

Website: https://www.kristinkirkpatrick.com/
Instagram: https://www.instagram.com/fuelwellwithkrissy/


**SPONSOR**

Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
https://tydewellness.com/GLP1Hub

Velogenix's Project Aeterna offers a free at-home mobility baseline and Pro assessments of strength, balance, and gait. Use code OFF for $50 off your first year of Pro.
https://velogenix.com

**CHAPTERS**

00:00 Why creatine is getting attention beyond the gym
01:30 Meet Kristin Kirkpatrick
03:22 Kristin's approach to integrative nutrition
06:09 What creatine does in the body
08:05 Creatine myths: Is it just for bodybuilders?
09:09 What the brain-health research can and cannot tell us
12:03 Creatine, strength training, and GLP-1 muscle health
15:13 Sponsor: Tyde Wellness
16:39 Monohydrate vs. HCl, dose, and timing
19:29 Gummies, powder, and the coffee question
23:24 Water retention, side effects, and the scale
26:07 Do you need a loading phase?
28:11 Sponsor: Velogenix
29:14 Muscle, mobility, and healthy aging
31:55 Can you build muscle after starting a GLP-1?
32:58 Connect with Kristin

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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What can getting out of a chair tell you about your muscle health? Ana Reisdorf, Registered Dietitian and GLP-1 user, joins muscle and bone researcher Mark Hamrick to explore staying strong during GLP-1 weight loss, perimenopause, and menopause. You'll learn what three simple assessments can reveal about physical function, and why muscle size alone doesn't tell the whole story.

Mark explains the differences between muscle mass, quality, strength, and power, and how they connect to everyday movement and healthy aging. Ana shares her own assessment results and asks whether her regular exercise routine is enough. They also discuss bone density, fall risk, and finding an approach to exercise that works when pain or physical limitations get in the way.

**IN THIS EPISODE**

- Why losing muscle size doesn't necessarily mean losing the same amount of strength
- What chair rises, single-leg balance, and walking speed can tell you about physical function
- How menopause, sleep, and activity levels enter the muscle-health conversation
- Resistance training, protein, and the research Mark discusses on creatine
- Adapting exercise with help from a physical therapist when movement is painful
- Bone density, DEXA scans, fall risk, and questions to bring to your healthcare provider

**ABOUT THE GUEST**

Mark Hamrick is president and co-founder of Velogenix and a former Regents Professor at the Medical College of Georgia. His research on muscle and bone aging has received NIH funding over the last two decades. He has published more than 225 peer-reviewed papers and advised NASA on muscle and bone loss in space. At Velogenix, he is applying that experience to tools for quickly assessing muscle health at home.

**CONNECT WITH MARK**

Website: https://velogenix.com
LinkedIn: https://www.linkedin.com/in/mark-hamrick-44b287121/

**SPONSORS**

Velogenix, co-founded by our guest, Mark Hamrick. Project Aeterna offers at-home assessments of strength, balance, and walking speed. Try the free baseline test, or use code OFF for $50 off your first year of Pro.
https://velogenix.com

Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
https://tydewellness.com/GLP1Hub

**CHAPTERS**

00:00 Why muscle and bone health deserve attention
01:27 Meet Mark Hamrick
02:39 Three simple assessments of physical function
05:11 Muscle size, quality, and the menopause transition
09:59 The connection between muscle and longevity
12:21 Walking, strength training, and protein
13:57 Everyday signs your strength may be changing
15:08 Sponsor: Tyde Wellness
16:33 What to do with your assessment results
17:48 Exercising with pain or physical limitations
19:13 Ana's results: Is regular exercise enough?
22:22 Sitting, standing, and moving more
24:08 Bone density, DEXA scans, and fall risk
28:46 Beyond the Shot guide
29:47 Mark's three takeaways for muscle and bone health
34:19 Try Project Aeterna and connect with Mark

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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You've reached your goal weight on a GLP-1. Now what: stay on it, lower the dose, or take a break? Ana Reisdorf, Registered Dietitian and GLP-1 user, joins pharmacist Dr. Stephanie Redmond to explore microdosing, cycling on and off medication, and the questions coming up around perimenopause and menopause. You'll hear where clinical experience meets unanswered questions—and why a smaller dose can still bring surprises.

Stephanie shares her own experience with low-dose side effects and returning hunger. Together, they discuss concerns about weight regain and muscle loss, telehealth screening, and why your long-term plan deserves as much attention as getting started.

**IN THIS EPISODE**

- What people mean by GLP-1 "microdosing" and why the term can be confusing
- Emerging uses beyond weight loss and diabetes, and where evidence is still limited
- Stephanie's experience with constipation, bloating, and returning hunger
- Questions about cycling, stopping treatment, and maintaining weight loss
- Perimenopause, menopause, insulin resistance, and individualized care
- The role of muscle preservation, nutrition, movement, and ongoing clinical support

**ABOUT THE GUEST**

Dr. Stephanie Redmond, PharmD, CDE, BC-ADM, is a pharmacist specializing in hormone health and diabetes management. She founded the Medication Therapy Management practice at Ridgeview Clinic System in Minnesota and has educated clinicians nationally on GLP-1 therapies. She is also the founder of Dr. Stephanie's®, a clinician-led supplement brand focused on GLP-1 support, hormone health, and women's wellness.

**CONNECT WITH STEPHANIE**

Website: https://drstephanies.com
Instagram: https://www.instagram.com/drstephanies
YouTube: https://www.youtube.com/@drstephanies

**SPONSORS**

Svalto Cooler Pro is a portable, battery-powered cooler for refrigerated medication. Use code GLP1HUB for 15% off.
https://svalto.com

Velogenix's Project Aeterna offers at-home assessments of strength, balance, and mobility. Take the free baseline test, or use code OFF for $50 off your first year of Pro.
https://velogenix.com

**CHAPTERS**

00:00 GLP-1 maintenance: What happens next?
01:34 Meet Dr. Stephanie Redmond
04:08 Emerging uses and gaps in the evidence
07:46 What does "microdosing" actually mean?
11:08 Telehealth screening and questions about inflammation
14:24 Sponsor: Svalto
15:20 Weighing the risks of low-dose use
17:05 Stephanie's personal experience with side effects
18:43 Cycling, returning hunger, and weight regain
22:39 GLP-1s, perimenopause, and menopause
26:59 Sponsor: Velogenix
27:58 The future of GLP-1 use and long-term planning
32:24 Connect with Dr. Stephanie Redmond
34:19 Stay connected with GLP-1 Hub

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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You can feel good about your GLP-1 weight loss and still wonder why your face looks different. Ana Reisdorf, Registered Dietitian and GLP-1 user, talks with wound-healing scientist Brian Pilcher, PhD, about what people call "Ozempic face," how volume loss differs from loose skin, and the treatment options available today. Could future treatments help the body rebuild some of its own tissue?

Brian explains the science behind tissue regeneration and what his company, Conexeu Sciences, is studying. Its technology remains preclinical, with safety and effectiveness still to be established in human trials.

**IN THIS EPISODE**

- How weight loss can change facial volume and skin support
- The differences between fillers, biostimulators, and skin-tightening treatments
- Why tissue regeneration involves cells, biological signals, and a supporting framework
- What early research can tell us, and what still needs to be tested in people
- Why wound-care development and potential aesthetic applications have different timelines
- Unanswered questions about GLP-1s and skin, plus caution around exosome claims

**ABOUT THE GUEST**

Brian Pilcher, PhD, is a wound-healing biologist and Chief Medical Officer of Conexeu Sciences. He brings more than 25 years of experience in dermatology and aesthetics, including leadership roles at BioForm Medical, Merz North America, and Suneva Medical. He holds a doctorate in cell and molecular biology from the University of Oklahoma College of Medicine. His research career included postdoctoral work at Washington University in St. Louis and a faculty position studying wound repair at UT Southwestern Medical Center. Today, his work focuses on translating tissue-repair science into the development of medical devices and potential regenerative treatments.

**CONNECT WITH BRIAN**

Conexeu Sciences: https://www.conexeu.com/

**SPONSORS**

Tyde Wellness offers clinician-guided GLP-1 care and ongoing support. Get $50 off your first month with code GLP1Hub50.
https://tydewellness.com/GLP1Hub

Calocurb is an appetite-support supplement made with Amarasate hops extract. Use code ANA10 for 10% off.
https://www.calocurb.com/

**CHAPTERS**

00:00 Facial changes after GLP-1 weight loss
05:23 What people mean by "Ozempic face"
08:58 What tissue regeneration actually means
13:51 Sponsor: Tyde Wellness
15:17 Targeting different tissues
16:27 Fillers, biostimulators, and skin tightening
21:27 What researchers still need to prove about safety
22:52 Human studies and the development timeline
26:32 Combining treatments and deciding when to start
28:23 Sponsor: Calocurb
29:22 Unanswered questions about GLP-1s and skin
30:45 Future research and caution around exosomes
33:42 Where to learn more and breast-tissue research
35:05 Stay connected with GLP-1 Hub

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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Your appetite is smaller on a GLP-1, but how do you know whether those few bites are giving you what you need? US Dietitian Ana Reisdorf and UK Nutritionist Rob Hobson explore how to put together balanced meals, make room for protein and fiber, and eat regularly without returning to calorie counting. They also unpack why familiar diet rules can make nourishing yourself harder when you’re already eating less.

**IN THIS EPISODE**
- What “every bite counts” means when your appetite and portions shrink
- Moving beyond calorie counting and fear of carbohydrates or healthy fats
- Finding a regular eating pattern that works with a low appetite
- Rob’s “rule of four” for building meals with protein, produce, a fiber-rich carbohydrate, and healthy fat
- Using convenient foods like precooked chicken, canned beans, and frozen vegetables
- Looking beyond high-protein labels and understanding where protein shakes can fit
- Understanding lean mass versus muscle loss and the role of resistance exercise
- Adding fiber gradually, staying hydrated, and taking a food-first approach to supplements

**ABOUT THE GUEST**
Rob Hobson is an award-winning Registered Nutritionist and Sunday Times bestselling author with over 20 years of experience in public health and sports nutrition. His latest book, Every Bite Counts, explores how to maximize nutrition when appetite is reduced, including during GLP-1 treatment. His practical approach focuses on building nutrient-dense meals that support muscle, energy, long-term health, and sustainable eating habits.

**CONNECT WITH ROB**
Instagram: https://www.instagram.com/robhobsonnutritionist
YouTube: https://www.youtube.com/@robhobsonnutritionist
Website: https://robhobson.co.uk
Every Bite Counts: https://theexperimentpublishing.com/catalogs/summer-2026/every-bite-counts/

**SPONSORS**
This episode is supported by Svalto and CaloCurb.

Svalto: Learn more about the Svalto Cooler Pro, the portable medication cooler for traveling with your GLP-1 or peptides medications, at https://svalto.com. Use code GLP1HUB for 15% off.

CaloCurb: Learn more about the plant-based supplement featured in this episode’s sponsor message at https://calocurb.com. Use code ANA10 for 10% off. Discuss supplement use with your healthcare provider.

**CHAPTERS**
00:00 Making every bite count with a smaller appetite
04:42 Nutrient density and moving beyond calorie counting
09:23 Eating regularly when you’re not hungry
12:55 Sponsor: Svalto
13:47 Building balanced meals with the rule of four
16:10 Convenience foods that make meals easier
18:31 Protein-added foods and when shakes can help
20:40 Protein, muscle, and resistance exercise
24:45 Sponsor: CaloCurb
25:45 Fiber, hydration, and starting small
27:37 A food-first approach to supplements
29:29 Building habits without chasing perfection
31:00 Where to find Rob and Every Bite Counts

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail

Poor sleep, mood changes, low energy, and new weight around the midsection can be easy to blame on aging or GLP-1 treatment alone. In this episode, Ana Reisdorf and Sharon Lemoine explore how hormone changes, thyroid function, insulin resistance, muscle loss, and lifestyle can overlap, and what a more complete evaluation may include. You’ll learn what to look for in a hormone-informed provider, why protein and muscle monitoring matter when using a GLP-1, and why a “normal” test result may not tell the whole story.

**IN THIS EPISODE**

- Sharon’s experience with type 1 diabetes, surgical menopause, Graves’ disease, and thyroid cancer
- What hormones do and why hormone-related symptoms can be difficult to recognize
- Common signs of changing estrogen, progesterone, and testosterone levels
- Why patients may still feel something is wrong after being told their results are normal
- Questions to discuss with a provider when considering hormone testing or therapy
- How menopause, muscle loss, and insulin resistance may contribute to changes in body composition
- Why protein, resistance training, and body-composition monitoring matter during GLP-1 treatment
- How Sharon decides when a GLP-1 may fit into a broader health plan
- Hormone-related symptoms and low testosterone in men
- How to find a qualified provider who listens and evaluates the complete picture
- Why hormone therapy requires an individualized discussion of potential risks and benefits

**SPONSORS**

CaloCurb:
https://calocurb.com
Use code ANA10 for 10% off.

Tyde Wellness:
https://tydewellness.com/GLP1Hub
Use code GLP1Hub50 for $50 off your first month.

**ABOUT THE GUEST**

Sharon Lemoine, MSN, ARNP, is a Nurse Practitioner, entrepreneur, public speaker, and advocate for a new model of healthcare that integrates faith, science, and personal responsibility. With more than 25 years of experience in emergency medicine and over 30 years in healthcare, Sharon has dedicated her career to helping patients move beyond symptom management and reclaim ownership of their health through hormone optimization, functional medicine, preventative care, and faith-based wellness principles.

**CONNECT WITH SHARON**

Website:
https://gigharbormedicalspa.com/

YouTube:
https://www.youtube.com/@SharonLemoine-ARNP


**CHAPTERS**

00:00 When Hormonal Symptoms Feel Overwhelming
00:26 What This Episode Covers
01:42 Meet Sharon Lemoine
02:42 Type 1 Diabetes, Surgical Menopause, and Thyroid Disease
07:13 What Hormones Do
08:29 Signs Your Hormones May Be Involved
10:57 Common Perimenopause and Menopause Symptoms
12:49 How Long Does Hormone Therapy Continue?
15:37 Sponsor: CaloCurb
16:36 Life After the Menopause Transition
17:35 Midsection Weight Gain, Hormones, and GLP-1s
20:41 Lifestyle and When a GLP-1 May Fit
22:04 Finding the Right Hormone Provider
23:05 Hormone Panels and Other Lab Tests
24:50 Hormone Concerns in Men
26:48 Sponsor: Tyde Wellness
28:13 Low Testosterone in Younger Adults
30:36 The Future of Hormone Health and Peptides
31:31 Hormone-Therapy Fears and Individual Risk
33:17 Connect With Sharon

MORE FROM GLP-1 HUB

📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.