May 10, 2023

#73: atropine (Isopto) | Used in Anesthesia, Bradycardia, and Organophosphate Poisoning

12 minutes

Atropine is an acetylcholine receptor antagonist that competitively inhibits autonomic effectors at muscarinic receptors. It has chronotropic effects and anticholinergic effects. Atropine comes in various injectable concentrations as low as 0.25mg/3mL up to 2mg/0.7mL. The most common side effects are xerostomia, blurred vision, tachycardia, constipation, dizziness, and headache. Some serious side effects are respiratory failure and pulmonary edema. Atropine is used in ACLS for bradycardia, anesthesia adjunct, neuromuscular blockade reversal adjunct, and for treating organophosphate poisoning.

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