Dr Glenn McConell chats with Associate Professor Chris Fry from the University of Kentucky, USA. Joint injury causes muscle weakness and atrophy (reductions in muscle size) due to the the inactivity but also separately due to the injury itself. Substances are released from muscle to help repair the joint/bone. Prehab is important before surgery. There can be residual effects long after joint injury. We also discussed hypertrophy and aging and the importance of having a lot of muscle capillaries as age to obtain the optimum response to resistance training. Lots more. We had a really great chat. Chris has a very pleasant manner. I enjoyed it a lot. Twitter: @ChrisFryPhD
0:00. Introduction and welcome
3:09. How Chris got into exercise research
6:10. ACL injuries and muscle wasting /weakness
9:05. Joint injuries and the risk of arthritis
10:05. The effects of the inactivity vs the injury itself
13:55. Protein synthesis vs breakdown after an ACL injury
19:30. Why in evolutionary sense does joint injury result in muscle atrophy
22:50. What are the signals to cause muscle atrophy
24:00. Myostatin release after joint injury
26:55. Acute vs chronic injury
28:15. Other joint injuries to joints (other than ACL)
29:25. Atrophy in different muscle fibre types
31:15. Best way to prepare for surgery after an injury
34:05. How quickly start rehab after surgery
35:45. Are there residual effects long after joint injury?
39:55. Bone vs joint injury
43:30. Muscle reactive oxygen species/ mitochondria after injury
46:05. Aerobic capacity of muscle still reduced after rehab
47:05. Should take anti inflammatories after injury?
49:20. Vitamin D and muscle injury
52:15. Does joint injury affect muscle in the non injuried limb?
54:45. What can do to slow atrophy after injury?
55:55. Does muscle size and strength go hand in hand after injury
57:15. Time since injury/trauma and surgery
58:55. Sex difference and joint injury
1:00:20. Age and joint injuries
1:01:10. Hypertrophy and aging
1:02:05. Aging: inactivity vs training response
1:03:00. More capillaries in muscle increases response to resistance training
1:05:00. Aerobic pre conditioning can help with hypertrophy
1:08:30. Anabolic resistance and aging
1:12:25. Connective tissue and training responses with aging
1:15:20. Satellite cells and muscle growth
1:17:45. Takeaway messages
1:19:01. Outro