Semi respected scientist and fascinating bastard, Edward Jessup (William Hurt) embarks on a study into schizophrenia using isolation tanks and eventually psychedelics with the help of his cohorts Drs, Rosenberg (Bob Balaban) and Parrish (Charles Haid). His studies are put on the back burner when he meets anthropologist, Emily (Blair Brown). They eventually marry, have a couple kids, and decide to split. Eddie takes the opportunity to go trip balls with the Hinchi tribe in Mexico with his guide, Eccheverria (Thaao Penghlis) and decides that if he uses the drugs and the tanks in conjunction he can break through the barrier to discover the original self. Things get weird when his hallucinations begin to materialize in the physical world and Jessup begins to lose his grip on reality and achieves Altered States, this week on Doom Generation. 

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