After a wave of high-profile pledges to bring pharmaceutical manufacturing back to the United States, a clearer picture of what reshoring actually looks like is starting to emerge. Tens of billions of dollars have been committed to new U.S. plants, but those investments are unlikely to translate into immediate gains in domestic production.

In this week’s episode of "The Top Line," Fierce’s Eric Sagonowsky sits down with Rosemary Coates, executive director of the Reshoring Institute, to unpack where the trend stands today and what comes next. Coates explains why the pharma industry is uniquely positioned to bring supply chains back to the U.S., and the challenges companies face as they try to do it.

To learn more about the topics in this episode: 

• UCB unveils plan to build $2B biologics plant near its US headquarters in Atlanta 

• Pharmas have promised $370B in US investments amid 2025's onshoring boom: DPR 

• Global pharma manufacturing output surged in '25 in 'front-loading' response to US tariff threats: report 

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