Today’s guest is Antonio Sersale, the owner and custodian of one of the world’s most beloved and sought-after hotels—Le Sirenuse in Positano. Since his family transformed it from a private holiday home into a legendary destination, Antonio has carried on their legacy, curating not just a hotel but an experience, a feeling, and a sense of place unlike any other.

Le Sirenuse is more than a luxury retreat—it’s a living collection. From its carefully chosen art and design collaborations to the meticulous attention to detail in every corner, Antonio has elevated the idea of hospitality into an art form. His passion for collecting extends beyond objects—it’s about moments, traditions, and the invisible thread that connects past and present.

We explore how Antonio selects artists for the Artists at Le Sirenuse program, the role of contemporary art in a historically rich setting, and the personal philosophy that guides both his hotel and his own growing collection. We also discuss the delicate balance of preserving history while embracing change, the small yet significant details that make a lasting impression, and the unexpected ways collecting and hospitality intersect.

Next time we do this, it will for sure be at Le Sirenuse, negroni in hand. But for now, please enjoy, this is Antonio Sersale, for Collectors Gene Radio.

Le Sirenuse - https://sirenuse.it/en/

Le Sirenuse Instagram - https://www.instagram.com/lesirenuse/?hl=en

Antonio Sersale's Instagram - https://www.instagram.com/antoniosersale/?hl=en

Cameron Steiner - https://www.instagram.com/cameronrosssteiner

Collectors Gene - https://www.collectorsgene.com