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Authentic Biochemistry
Authentic Biochemistry episodes
- ImmunoEpigenetics59. The P53/AKT/PHLDA3 axis over tumorigenicity is controlled by endomembraneous targeting via glycerol lipid PhosphatidylInositol bis-phosphate (PIP2) phosphorylation to PIP3.5.12.23
References
Int J Mol Sci. 2020 Jun; 21(11): 4098.
Authentic Biochemistry lectures :ImmunoEpigenetics 56-58
30 min - ImmunoEpigenetics 58. Epigenetic mechanisms role in Loss of Heterozygosity (LOH) in TSG's advancing targeting of solid tumors via pharmacotherapeutic CAR-T cells. DJGPhD 27.4.23. Authentic Biochem.
References
BMC Medical Genomics. 2015. volume 8, Article number 45.
Journal for ImmunoTherapy of Cancer 2022;10:e003826.
30 min - ImmunoEpigenetics 57. Plasmacytoid dendritic cell neoplasias and the CAR-T cell tumor microenvironment exposure altering epigenetic TF regulation leading to diverse differentiation. DJGPhD.20.4.23
References
Current Oncology Reports. 2020. 1534-6269, May 15, Vol. 22, Issue 6.
Cell. 2021 Dec 9; 184(25):6081–6100.e26.
30 min - ImmunoEpigenetics 56. Dendritic cell immunobiochemistry introductions. DJGPhD. Authentic Biochemistry 15.4.23
References
Autoimmunity. 2012 Aug;45(5):333-47
Clinical and Experimental Rheumatology 2019: One year in review 2019: systemic lupus erythematosus
Trends in Immunology, 2021-01-01, Volume 42, Issue 1, Pages 59-75
Annu. Rev. Immunol. 2000. 18:767–811
29 min - ImmunoEpigenetics55. ILC and Treg differentiation is mediated by acetylation and methylation epigenegtic authorship at discrete TF binding site domains.DJGPhD.14.4.23. Authentic Biochemistry
References
Cell Reports 2015 10, 2043-2054DOI
ID2_HUMAN,Q02363
Experimental & Molecular Medicine 2019. volume 51, Article number: 80.
29 min - Immunoepigenetics 54. Macrophages, T lymphocytes and neutrophils each comply with epigenetic alterations to mediate the inflammatory response. DJGPhD.12April.2023.Authentic Biochemistry
References
Guerra's notes
30 min - ImmunoEpigenetics 53.The metaphysics of biochemical control within epigenetic alteration of gene expression as obtained in macrophage mediated immune activation. DJGPhD.7April23'Authentic Biochem
References
Dr Guerra's lecture notes-Immunology
DJGPhD writings on Middle Platonist Metaphysics in Biochemistry: unpublished
Curr Opin Biotechnol. 2020 Jun; 63: 111–117
30 min - ImmunoEpigenetics 52. Integration of intermediary metabolism with epigenetic modification of immune cell activation and proliferation.DJGPhD. 5April23. Authentic Biochemistry Podcast.
References
Curr Opin Biotechnol. 2020 Jun; 63: 111–117
Epigenomics. 2019. VOL. 11, NO. 68 May
Front.Genet., 23 October 2018 Sec. Epigenomics and Epigenetics Volume 9.
30 min - ImmunoEpigenetics 51. The Glutamine contribution to tumor bioenergetics and lipogenesis and the role of storage TAG in macrophage pro-inflammation. DJGPhD. 29.3.23
References
Nature Communications 2020.volume 11, Article number: 4107.
Nutrire 2016. volume 41, Article number: 14
28 min - ImmunoEpigenetics 50. Malic Enzyme serves as a cytosolic circuit to generate pyruvate from glutamine to drive cancer cell division by altering TCA flux and indirectly, cell cycle progression.DJGPhD
References
Cell 2012 148DOI: (10.1016/j.cell.2012.01.031)
Biotechnology Journal 2016. Volume11, Issue1 Special Issue: Biotech Methods and Advances: 71-79.
Molecular Cancer. 2020. volume 19, Article number: 39.
30 min
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.