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Authentic Biochemistry
Authentic Biochemistry episodes
- ImmunoEpigenetics XXXIX. T cell acute lymphoblastic leukaemia genetics and epigenetics: the role of chromatin retailoring via histone LYS acetylation/deacetylation event ontology. DJGPhD.3March23
References
Genes (Basel). 2021 Aug; 12(8): 1118.
Nature Reviews Immunology 2018. volume 18, pages 617–634.
30 min - ImmunoEpigenetics XXXVIII. Tcell receptor activation and the PIP3/AKT/mTORCI/mTORCII control over cytokine expression:a primer. DJGPhD.2March2023.Authentic Biochemistry Podcast.
References
Guerra's immunology lectures
Experimental & Molecular Medicine volume 51, Article number: 80 (2019)
Genes (Basel). 2021 Aug; 12(8): 1118
30 min - ImmunoEpigenetics XXXVII. Differential substrates for the Adenylate Cyclase-PKA phosphorylation cascade distributes assymetric inflammatory, hormonal and metabolic sequalae. DJGPhD.01March23.
REferences
Dr Guerra's graduate biochemistry lectures
J Biol Chem. 2013 Mar 8; 288(10): 7137–7146
30 min - ImmunoEpigeneticsXXXVI. Tumor-specific methylation respondent transcription of Adenylate Cyclase 2 may be linked to differential cytokine expression controlling T cell activation. DJGPhD.01March23.
References
Naunyn Schmiedebergs Arch Pharmacol . 2014 Apr;387(4):329-39.
J Biol Chem. 2013 Mar 8; 288(10): 7137–7146
J Anim Sci. 1998 Jan;76(1):160-72
Journal of Bone Oncology 2017. Volume 9: 34-40
30 min - Immunoepigenetics XXXIV. Methylation signatures in neoplasias1. DJGPhD. Authentic Biochemistry Podcast Productions. 26.2.23
References
Journal of Bone Oncology 2017. Volume 9, November. Pages 34-40
Journal of Disease and Global Health 15(3): 22-47, 2022.ISSN: 2454-1842, NLM ID: 101664146
https://www.ikppress.org/index.php/JODAGH/article/view/8023
30 min - ImmunoEpigenetics XXXIII. Crisper CAS , small molecule,and LOXP-CRE targeting of SDH/ComplexII decrease Th1 cytokine production: Standard Oxidation Potentials and TCA anapleurotic involvement.DJGPhD.
References
Nature. 2019 Jul; 571(7765): 403–407
Dr Guerra's lectures
30 min - ImmunoEpigeneticsXXXII. Apriori synthesis of the glycolytic/TCA/ETC axis mediating target and endogenous apoptotic control with Th and NK cell activation/proliferation and effector function. DJGPhD.
References
Authentic Biochemistry Podcast Immunoepigenetics lectures XXIX-XXX1
Dr. Guerra's intermediary metabolism and bioenergetics lectures
Nature. 2019 Jul; 571(7765): 403–407
30 min - ImmunoEpigenetics XXXI. The role of SDH on Complex II electron flow to ubiquinone subsequent to cardiac arrest is associated neuronal PCD similar to Tcell bioenergetic switching during activation.
References
J of Intensive Care. 2020. volume 8, Article number: 60.
Neuroscience. 2018 Nov 21;393:24-32
Cancers 2020, 12(11), 3237
Nature. 2019 Jul; 571(7765): 403–407
30 min - Immunoepigenetics XXX.NK lymphoyctes programed tumor cell death by titrating anti-apoptotic BCL proteins with BH3 pro-apoptotic events. DJGPhD. 17.2.23. Authentic Biochemistry Podcast
References
Cancers (Basel). 2020 Aug; 12(8): 2137.
Cell Death Dis. 2020 Jan 2;11(1):5
Cell. 2022. 185. 9. :521-1538.e18
30 min - ImmunoEpigenetics XXIX. Apoptosis unthwarted:preventing phosphorylation of RNAPOLII tanks histone acetylation near Mcl enhancer region thus epigenetically inhibiting expression in glioblastoma cells.
References
Cell Death & Differentiation 2020.27: 3374–3385
Cell Death & Differentiation 2019. 26: 1501–1515
Cancers 2020, 12(8), 2137.
30 min
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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.