Winter pressures and COVID-19 have catalyzed a blood supply crisis around the world. As part of National Blood Donor Month in the United States, Dr. Hilary Guite investigates blood transfusions with Maria Cohut, Medical News Today’s feature editor, and Dr. Baia Lasky, medical director of the American Red Cross. Hilary and Maria also speak with Shaun, a blood donor, about the process of giving blood, and hear from blood transfusion recipient-turned-donor, Brian.