The wealthy real estate tycoon Alexander brothers are charged with conspiring to drug, sexually assault, and rape dozens of women, according to investigators. Their Federal trial is set to begin at the end of January. In this episode, we investigate the allegations that stretch from South Florida to New York.

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2025 was a busy year with many of the cases I'm covering including Nick Reiner, alleged Charlie Kirk assassin Tyler Robinson, the mysterious cruise ship death of Anna Kepner, Sheriff Stines accused of killing Judge Mullins, and the D4vd case -- among many others. In this episode -- I look ahead to 2026 what key developments could come in the biggest cases.

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The family of Sydney Marquez says they are clueless about where she could have disappeared to or how she went missing. The 24-year-old has been missing since Dec. 11th. Surveillance video showed her last seen walking near the hotel where she was staying while in Houston visiting friends. In this episode, we investigate what may have happened -- and also discuss the tragic end to another Texas case.

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A Utah judge unsealed a court transcript in the Tyler Robinson case. Robinson is accused of assassinating Charlie Kirk. The new transcript was kept secret for over a month — and certain parts are still redacted. In this episode — we analyze what the redacted portions could mean and the defense’s fight to get prosecutors thrown off the case.

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Reports indicate police were called to the Reiner home numerous times dating back to 2013. The calls included a mental health related check and battery of family violence investigation. But could there have been more incidents involving Nick Reiner that were not reported officially to police? We’re looking into that — and also the time of death and a possible insanity defense in this episode of Brian Entin Investigates.

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Is Nick Reiner legally insane -- and if his defense attorney can successfully argue he is -- would that keep him out of jail forever? In this episode, former FBI profiler Jim Clemente shares his thoughts on Reiner and whether an insanity defense could work in California where the law is especially unique.

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A 73-year-old true crime producer turned phony heiress with ties to Los Angeles is on the run after reportedly conning several high-profile financial institutions out of nearly $30 million, officials with the Federal Bureau of Investigation say.

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The possible motive for Brown University shooter Claudio Manuel Neves Valente is starting to come into focus. A former classmate shares his story about Valente at Brown -- as we learn more about possible warning signs the university missed leading up to the shooting. And a criminal profiler weighs in on why Valente also allegedly shot an MIT professor.

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There are several developments in the Charlie Kirk alleged assassin Tyler Robinson's ongoing criminal case. The defense is trying to get the prosecution team thrown off the case. Also, new messages from Robinson to a friend on the day of the assassination have surfaced. And the judge still has to decide whether cameras will be allowed to remain in the courtroom.

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Nick Reiner, son of Hollywood director Rob Reiner and his wife, Michele Reiner, was reportedly diagnosed with schizophrenia and was being treated by a psychiatrist in the weeks leading up to his parents’ murders. But did he actually have schizophrenia? In this episode of Brian Entin Investigates, Dr. Drew Pinsky explains why he believes it's not schizophrenia, but instead the murders were brought on by meth psychosis.

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