CNN One Thing

As a measles outbreak continues to grow in West Texas, questions are mounting over the quality of federal response, as Health and Human Services secretary Robert F. Kennedy Jr. downplays the outbreak’s severity. We ask a Houston doctor if he’s expecting a major livestock show to bring more measles cases to his city. Meanwhile, experts fear disrupted meetings about vaccines could threaten timelines and transparency from health officials around other key shots.

Guests: Meg Tirrell, CNN Medical Correspondent & Dr. Wesley Long, Director of Microbiology at Houston Methodist Hospital

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Some progressive groups are calling for an ‘economic blackout’ on Friday, urging Americans not to purchase anything from major retailers in protest of corporate greed and Trump administration actions. But what could it accomplish? We examine why similar calls to boycott companies retreating from DEI policies could have unintended consequences.

Guest: Nathaniel Meyersohn, CNN Business Reporter

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As the Trump administration works to carry out its mass deportation operation, undocumented immigrants without criminal records fear being caught up in potential raids at schools, churches, or other places in their communities. In this episode, we hear from people doing what they can to fight back.

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As US and Russian officials meet about the war in Ukraine - without Ukraine - European leaders are feeling similarly sidelined. Meanwhile, Germany’s controversial far-right party could make major gains in elections on Sunday – and Elon Musk is cheering them on.

Guest: Sebastian Shukla, CNN Producer 

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If you’ve been to the grocery store recently, you know egg prices are through the roof (if you can even find any). We explore how a growing avian flu outbreak is frustrating farmers and hindering President Donald Trump’s plans to lower prices.

Guests: Doug Corwin, President of Crescent Farms & Vanessa Yurkevich, CNN Business and Politics Correspondent

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As many of President Donald Trump’s sweeping executive actions get challenged in court, some on the right are suggesting his presidential power could exceed certain legal rulings. We examine the implications of ignoring court orders and what could put us on a path towards a constitutional crisis.

Guest: Paula Reid, CNN Chief Legal Affairs Correspondent

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Many aid programs around the world have been paralyzed in the wake of the Trump administration’s 90-day pause on foreign aid. We hear how an Elon Musk-led effort to dismantle the US Agency for International Development (USAID) is already having ramifications at home and abroad.

Guests: Teddy Ruge & Brian Aliganyira

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Some federal employees are on edge as Elon Musk continues his work on behalf of President Donald Trump to overhaul the federal government in unprecedented ways. We examine just how sweeping his actions are and why resistance to them is growing. 

Guest: Zachary Wolf, CNN Politics Senior Writer

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In the days since the deadly midair collision outside Washington DC, questions are being asked about what could have contributed to the tragedy. We hear from an expert who says the push for more flights isn’t making jobs easier for a workforce already stretched thin.

Guest: David Soucie, CNN Safety Analyst/Author, ‘Safer Skies’ 

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Wall Steet, Washington, and Silicon Valley are scrambling after a little-known Chinese startup claimed its artificial intelligence model can operate like ChatGPT at just a fraction of the cost. We examine why the breakthrough could reverberate beyond the tech sector as President Donald Trump looks to counter China's influence.

Guest: Matt Egan, CNN Reporter

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