Since it’s discovery, CRISPR Cas9 gene editing technology has blossomed and boomed.  It’s moved from a highly technical niche technique to one that is arguably mainstream and being applied to countless challenges in applied biology. In this episode we talk with Travis Hardcastle, who previously worked in R&D to develop gene editing products and is now a Product Manager for Engineered Cell Lines at Synthego. Travis helps explain the basics of gene editing and how it’s being applied to cell line engineering and provides a well-informed perspective on the past, present, and future of the CRISPR revolution. This conversation touches on automation, bioproduction, and the feedback loop of guide DNA and cell line development. The therapeutic application of this technology, which has the potential to truly enable personalized medicine, is a focal point of this personal and informative conversation.  

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