Daiichi Sankyo has been pioneering ADCs since 2010, with a pipeline targeting over 30 indications and potentially reaching 400,000 patients.

In today’s episode I’m joined by Dr. Markus Kosch, Head of the EU Oncology Business Division at Daiichi Sankyo. A physician by training with a deep academic background in oncology, Markus has spent over two decades advancing cancer care, from clinical practice to leadership roles shaping strategy across Europe and Canada. Since joining Daiichi Sankyo in 2021, he has been at the forefront of one of the industry’s most ambitious ADC pipelines, overseeing more than 60 clinical trials across 24 countries and driving landmark approvals that are redefining treatment in breast, lung, and gastric cancers.

This week's episode is brought to you with the support of Kadans. 

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01:45.         Meet Markus Kosch

03:12.         Clinical background shaping an industry role

04:46.         Daiichi Sankyo’s 40-year oncology legacy

06:19.         European investments and Munich hub

10:34.         ADC platform strengths explained

14:20.         Key ESMO 2025 trial data

Clarification: The reference to ‘TB01’ at 16:24 refers to the TROPION-Breast02 clinical trial, not TB01.

19:43.         Managing risks and partnerships

23:35.         Patient advocacy in trial design

33:59.         Future of oncology and ADCs

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To dive deeper into the topic: 

• 10 oncology deals in 2025 spotlight where industry leaders are betting big
• AstraZeneca and Daiichi Sankyo’s Enhertu recommended for approval
• Ten drugs to watch in 2025: will these therapies become blockbusters?