Dr. Suresh Durgam (Intra-Cellular Therapies, a Johnson & Johnson Company, Bedminster, NJ) joins AJP Audio to discuss a phase 3 randomized controlled trial looking at the use of the antipsychotic medication lumateperone as adjunctive to antidepressant therapy in the treatment of patients with major depressive disorder. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the rest of the December issue of the Journal.

• 00:48 Durgam interview
• 03:09 Mechanism of action
• 04:44 Patient-reported outcomes
• 06:31 Immediate clinical implications
• 07:32 Limitations
• 08:08 Further research
• 09:25 Kalin interview
• 09:38 Durgam et al.
• 13:09 Lin et al.
• 17:22 Brodsky et al.

Transcript

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