Eledon's CEO, Dr. David-Alexandre Gros, breaks down Tegoprubart, the company’s targeted immunosuppressant being studied alongside islet cell transplants for type 1 diabetes. The conversation covers the promising results seen so far, including insulin independence and improved A1C levels among trial participants, and why Tego could offer a different approach to protecting transplanted cells. The episode also explores what the future of type 1 diabetes treatment could look like as transplantation, stem-cell-derived islets, and new immunosuppressive therapies continue to advance.

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Watch Next: Type 1 Diabetes Cure Research 

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DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.

Ever wonder what insulin pump options exist outside the U.S.? Dr. Inge Van Boxelaer, a Belgian endocrinologist and founder of Diabetotech, joins us on the podcast and breaks down the European AID system landscape. We cover how MiniMed, Tandem, and Omnipod are performing across European markets, plus a deep dive into European systems like the Kaleido, mylife YpsoPump (with CamAPS FX and the upcoming Liberty algorithm), the Diabeloop-powered systems, and the Medtrum Touchcare. The conversation also explores how reimbursement and regulatory approval vary wildly by country, and where the market is headed next with patch pumps, phone-controlled systems, and fully closed-loop technology.

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Check out Diabetotech

Podcast: Medtrum User Interview, CamAPS FX Explained

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DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.

Part two of this series continues the conversation about what a cure for type 1 diabetes could actually look like, from cell replacement and immune therapies to insulin innovation and advanced diabetes technology. The discussion explores islet cell transplants, stem cell-derived beta cells, immune suppression, gene-edited cells, and the challenges of making these approaches safer and more widely available. The expert panel also break down why even the most advanced technology today still falls short of a true cure. A major focus is accessibility, including who could benefit from these therapies, how much they might cost, and the infrastructure needed to deliver them to millions of people with type 1 diabetes. The experts discuss their vision for the future of cure research and how far off it could be.

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Could Prevention be the Cure for Type 1 Diabetes?

The Cure Post-Show Reaction

Diabetech Feedback Survey

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DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.

In this episode, I sit down with leading type 1 diabetes researchers and clinicians to break down the science behind prevention, delaying disease progression, and replacing insulin-producing beta cells. We explore promising therapies like teplizumab, ATG, and verapamil, along with the challenges of immunotherapy, beta cell replacement, and making these treatments accessible to more people. This conversation also tackles why we’ve been hearing “a cure in 5 to 10 years” for so long, what researchers have learned about the root causes of type 1 diabetes, and why there’s more progress happening now than ever before.

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Inside the Vertex Participant Who's Cured of Type 1 Diabetes - Patti Columbe

The Cure Post-Show Reaction

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DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.

When your CGM fails, your pump dies, or you're caught in a situation without access to your tech, do you know what to do? Gary Scheiner and I break down the "back to basics" skills every T1D needs to know from manual carb counting to calculating correction doses without a pump, to safely transitioning from a pump to MDI (and back again). We also cover what belongs in your diabetes emergency go-bag and how to best manage your care in the event of a natural disaster.

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Integrated Diabetes - work with Gary and his team

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Emergency Resources: 

FRIO (10% off JUSTIN10)

Your'e Just My Type

Grown Up T1D

Breakthrough T1D

DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.

A cure for type 1 diabetes has always felt like a distant idea, but for Patti Columbe, it's now her reality. After living with type 1 for 40 years, Patti shares her journey as a participant of the Vertex VX-880 clinical trial, where a lab-grown islet cell transplant has left her insulin-free and functionally cured. She opens up about the emotional challenges of adapting to life without diabetes and why she believes hope is finally becoming reality for the T1D community. This conversation also explores the future of stem cell therapies, immunosuppression, and what it could take to make these treatments available to more people.

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Learn about the Eversense 365 CGM

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DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.

MiniMed’s new tubed insulin pump is finally here, and early users are beginning to share what life with the new insulin pump is really like. Our guests discuss using the system, the transition from previous pumps, what surprised them most, and how the smaller, app-controlled pump has impacted their day-to-day. The conversation also explores MiniMed's Meal Detection technology, how the algorithm handles missed or underestimated boluses, and what users would still like to see improved. Plus, stay until the end for a brand-new post-show discussion comparing the Flex to other insulin pump options and sharing the team's candid first impressions.

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T1D Exchange Registry (affiliate)

MiniMed Interview with CTO

Waterproof Connection Data 

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DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.

Greg Peterson has lived with type 1 diabetes for nearly 70 years and used an implantable insulin pump for more than two decades, even traveling from the U.S. to France to maintain it after the technology was discontinued. He shares how the implantable pump worked, how it dramatically improved his quality of life, and the profound impact it had on managing highs and lows as well as his relationships with loved ones. Two companies are currently working to bring next-generation implantable insulin pumps back. This conversation dives into the history of this remarkable technology, why it disappeared, and what the future could hold for implantable insulin pumps.

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DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.

I sat down with diabetes technology expert, and pharmacist, Diana Isaacs to compare every AID pump currently available in the Unites States. We dive into how each system works, who it's best suited for, and the features that truly set them apart; from Omnipod 5's tubeless form factor and Sequel's twiist DIY roots to Tandem's Control-IQ+ algorithm, the screenless MiniMed Flex, and the ease of Beta Bionics iLet. We discuss real-world pros and cons and explain what matters most when deciding on your next pump. Whether you're switching systems or considering your first pump, this conversation can help you better understand your options.

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Reviews & Resources: Omnipod 5, twiist, Tandem Mobi, Tandem tslim X2, MiniMed Flex, Beta Bionics iLet, Omnipod Recycle Program 

DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.

Gary Scheiner, CDCES, and I break down why carb counting is one of the trickiest parts of managing type 1 diabetes, and why getting it "close enough" is often more realistic than getting it perfect. We dive into how fat, protein, fiber, and alcohol each affect blood sugar differently, plus why insulin timing matters just as much as the dose. Gary shares practical estimation strategies like the hand and fist method, carb factors, and using AI tools and apps to get quick, accurate counts on the go. We also cover common "kryptonite foods" that trip people up and how to use CGM and pump data to fine-tune your ratios over time.

Learn about the Eversense 365 CGM

Learn about Omnipod 5 (today's sponsor)*

Integrated Diabetes - work with Gary and his team

Join the T1D Exchange Registry (affiliate)

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Carb Counting Quiz

SNAQ App

DISCLAIMER: This podcast is not medical advice and is for educational purposes only. Always consult with your doctor before making changes to your health care. 

*10-day trial eligibility may vary. Full terms and conditions apply. Visit omnipod.com/diabetech for clinical disclaimers, terms and important safety information. The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof.