Is knowledge of all knowledge, including of that which is not knowledge, logically possible? This, among other questions, was the subject of discussion in this March 14, 2021 live recording of a discussion of the Toronto Philosophy, Calgary Philosophy, and Online Rebels Meetup groups. The range of our own dialogue covered the nature of self and of temperance, which Plato represents as the “science of self”, and Socrates’ words that “…it was not living scientifically that was making us fare well and be happy, even if we possessed all the sciences put together but that we have to have this one science of good and evil.”