Actor and comedian Ilana Glazer joins the show. Over celebrity chicken and crab leg curry, Ilana tells me about their motherhood inspired Hulu standup special 'Human Magic,' their iconic meet-cute with their now husband, and hilarious conversations they've had with their doctor. This episode was recorded at Jitlada in East Hollywood, CA.

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Introducing Why 90% of Alzheimer's cases are preventable | Drs. Ayesha and Dean Sherzai from ZOE Science & Nutrition.

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Dementia is one of the fastest-growing health crises in the developed world, with cases expected to double in the coming decades. But despite common misconceptions, cognitive decline isn’t inevitable. The latest research shows that lifestyle choices play a far greater role in brain health than genetics alone.

In this episode, neurologists Drs. Ayesha and Dean Sherzai share practical, science-backed strategies to help you protect your brain and reduce your risk of dementia.

As co-directors of the Alzheimer’s Prevention Program at Loma Linda University, they’ve spent their careers studying how habits like diet, exercise, sleep, and stress management influence long-term cognitive health.

🥑 Make smarter food choices. Become a member at zoe.com - 10% off with code PODCAST

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*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

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Timecodes

00:00 Meet the brain doctors fighting dementia

01:04 Parents have dementia – are you doomed?

02:00 Can dementia be reversed?

02:25 Five lifestyle changes to prevent Alzheimer’s

06:07 What is dementia vs. Alzheimer’s?

08:50 Are your genes to blame?

12:49 Dementia starts 20+ years before diagnosis

14:10 Four biggest causes of Alzheimer’s

19:04 How to build brain reserve & stay sharp

22:50 Are dementia rates rising or falling?

25:30 How the brain declines over decades

29:00 This diet cuts Alzheimer’s risk by 53%

32:40 Three nutrients your brain can’t live without

38:15 The surprising link between LDL cholesterol & dementia

44:10 Leg workouts slash dementia risk by 35%

46:20 Why strength training is critical for brain health

50:36 How stress shrinks your brain

54:00 Sleep: The brain’s natural detox

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Free resources from ZOE

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Mentioned in today's episode

Association of Lifestyle and Genetic Risk With Incidence of Dementia, 2019, published in JAMA

Dementia statistics, published by Alzheimer's Disease International (ADI) 

World Alzheimer Report 2015 - The Global Impact of Dementia, published by Alzheimer's Disease International (ADI) 

Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later, 2009, published in Dementia and Geriatric Cognitive Disorders 

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Tony-award winning actor Nathan Lane joins the show. Over spicy yellowtail sashimi and coconut prawns, Nathan tells me about his new sitcom ‘Midcentury Modern,’ how he almost didn’t do ‘The Birdcage’ and the iconic audition that led to him being Timon in ‘The Lion King.’ This episode was recorded at Crustacean in Beverly Hills, CA.

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Introducing Do vitamin D supplements work? | Prof. Tim Spector and Dr. Federica Amati from ZOE Science & Nutrition.

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Vitamin D is the world’s favorite supplement. Governments around the world recommend people take the supplement for at least six months out of the year. But do we really need these pills? Do they even work? And could they actually be harming us?

In this episode, two ZOE scientists - Professor Tim Spector and Dr Federica Amati reveal the truth about vitamin D.

Tim is scientific co-founder of ZOE and professor of epidemiology at King’s College London. Federica is head nutritionist at ZOE and author of the Sunday Times bestseller ‘Every Body Should Know This’.

🥑 Make smarter food choices. Become a member a zoe.com - 10% off with code PODCAST

🌱 Try our new plant based wholefood supplement - Daily 30+

*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

Follow ZOE on Instagram.

Timecodes:

00:00 The sunshine vitamin

01:50 Quickfire questions

04:05 What is vitamin D?

07:12 Is sunlight the best source of vitamin D?

09:40 Does vitamin D keep my bones strong?

15:34 Are vitamin D levels a marker of good health?

20:00 What counts as normal levels of vitamin D? 

24:42 Supplement controversy

29:10 Do calcium supplements help bones?

31:29 Can I take too much vitamin D?

37:50 Could vitamin D prevent these health conditions?

42:54 Tim’s sunscreen controversy

46:46 Vitamin D and immunity

Books by our ZOE Scientists:

Mentioned in today’s episode:

Other ZOE Science & Nutrition episodes to try:

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

‘Thelma’ star June Squibb joins the show. Over grilled cheese, June tells me about exotic dancing for her audition for ‘Gypsy’ on Broadway, getting her first Oscar nomination in her eighties for ‘Nebraska,’ and how Beanie Feldstein helped her get her first leading role.  This episode was recorded at Zinc Cafe & Bar in West Hollywood, CA.

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Introducing 4 immunity tips for healthy ageing | Dr. Jenna Macciochi from ZOE Science & Nutrition.

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Over the last two years, there’s been a rise in “immune-boosting” foods, supplements and trends. Today's guest, immunologist Dr. Jenna Macciochi, believes the immune system doesn’t need boosting. Instead, it should be balanced.

In this episode, Jenna - a Senior Lecturer in Immunology at the University of Sussex - reveals how your immune system is your body’s housekeeper. Jenna highlights the case for the ‘good bugs’ in our gut microbiome, the role of micronutrients and how our immune system isn’t born, but made.

We'll also tackle the age-old question: do we really need Vitamin C supplements?

🥑 Make smarter food choices. Become a member at zoe.com - 10% off with code PODCAST

🌱 Try our new plant based wholefood supplement - Daily 30+

*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

Follow ZOE on Instagram

Timecodes:

01:21 Quickfire questions

04:51 What is the immune system?

06:49 How your immune system works

09:35 What are natural killer cells?

14:18 Is your immune system inherited?

16:42 The impact of sleep and stress 

19:53 Cancer and immunotherapy

28:23 This can trigger inflammation

30:25 Are vitamin C supplements worth it?

31:30 Foods to empower your immune system

40:10 How inflammation affects your brain

44:10 New science of the impact of stress

48:52 Immunity and your body clock

📚 Get Jenna's book Your Blueprint for Strong Immunity

📚 Books by our ZOE Scientists:

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Mentioned in today’s episode:

“Immune Boosting” in the time of COVID: selling immunity on Instagram (2020), published in Allergy, Asthma & Clinical Immunology

Vitamin C for preventing and treating the common cold (2013), published in Cochrane Database of Systematic Reviews

Effects of stress on immune function: the good, the bad, and the beautiful (2014), published in Journal of Immunology Research

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Oscar-winning actor Kathy Bates joins the show. Over pizza and a caprese salad, Kathy tells me about who she wishes was her Oscar date the year she won, an iconic drink with Meryl Streep and why she's having the most fun she's ever had leading the Paramount + reboot of 'Matlock.' This episode of Dinner’s On Me was recorded at La Bettola di Terroni in Larchmont Village, CA.

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Introducing Ozempic & Weight Loss Drugs: How They Work in Your Brain | The Oprah Podcast from The Oprah Podcast.

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In this episode of The Oprah Podcast, Oprah sits down with Dr. Ania Jastreboff, an endocrinologist and associate professor at the Yale School of Medicine, to talk about the new GLP-1 medications like Ozempic, Wegovy, Mounjaro and Zepbound. Dr. Ania, who has been on the forefront of GLP-1 medication research for the past 20 years, will talk through why it is biologically difficult for some people to lose weight, maintain weight loss and why obesity is a disease. She explains how the new GLP-1 medications work, how they can facilitate weight loss, and if they are safe. Dr. Ania answers questions from people around the country who are taking the GLP-medications and have lost a significant amount of weight. We will also share an update from Amy Kane who told her story of losing 160 pounds on weight loss medications last year on Oprah’s ABC Special: Shame, Blame and the Weight Loss Revolution.

Also referenced in this episode: "The Let Them Theory: A Life-Changing Tool That Millions of People Can’t Stop Talking About" by Mel Robbins, published by Hay House LLC is available wherever books and audio books are sold.

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DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Cabaret star, actor and producer Bridget Everett joins the show. Over some deliciously hot griddle cakes, Everett tells me about the special connection she has to her HBO show “Somebody Somewhere,” why “Sex and the City” co-creator Michael Patrick King is such an important person to her, and the interesting place she put her late mother’s ashes. This episode was recorded at Salt’s Cure in Hollywood, CA.

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Introducing Blood sugar hacks to give you more energy | Glucose Goddess Jessie Inchauspé and Prof. Tim Spector from ZOE Science & Nutrition.

Follow the show: ZOE Science & Nutrition

Why do some people feel fine eating lots of carbs when others feel energy slumps? Is blood sugar to blame?

In this episode, we learn why blood sugar varies so much between people, and the tools to manage these levels. 

Tim Spector and Jessie Inchauspé (aka the Glucose Goddess) will discuss the latest science around glucose control, what the cool new device on the block – the CGM – can tell us and why blood sugar levels are only one part of the picture of our health.

Jessie is a bestselling author and science communicator with a community of over 5 million followers. Tim is a professor of epidemiology at King’s College London and ZOE’s scientific co-founder.

🥑 Learn how your body responds to food 👉 zoe.com/podcast for 10% off

🌱 Try our new plant based wholefood supplement - Daily 30

*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

Follow ZOE on Instagram.

Timecodes:

00:00 Introduction

01:14 Quickfire questions

02:39 What is glucose?

07:50 What are blood sugar spikes?

09:15 Are lots of spikes dangerous?

10:45 What happens when your blood sugar spikes?

14:03 Should I worry about blood sugar levels?

15:11 HbA1c and fasting glucose explained

19:30 What are CGMs?

23:24 How breakfast impacts the rest of your day

29:07 Eat these foods first

33:12 Can physical activity reduce spikes?

35:46 How gut microbiome and blood fat play a role

41:39 The risks of ultra-processed foods

Find more from Jessie at glucosegoddess.com 

Books by our ZOE Scientists:

Free resources from ZOE:

Studies relevant to this episode:

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].