Big shift in Alzheimer's care!

We can now predict it years in advance using 🩸 biomarkers like p-tau217, 🧬 genetic risk, & 🤖 AI-analyzed retina scans.

Prevention = lifestyle 🥦🏃‍♂️💤, vaccines 💉, & maybe GLP-1s 💊.

Why wait to treat when you can PREVENT? 🔍

#Alzheimers #PrecisionMedicine #AI

🧬 Did you know your blood cell metabolism could fuel heart disease?

🔁 Disrupted haematometabolism = more inflammation, less cleanup

🧹 Efferocytosis fails → plaques grow

🧠 Aging + CHIP mutations = 🔥 risk

🥗 Fix it with fasting, fitness & future therapies!

#CardioTwitter #MedEd #Haematometabolism ❤️

🧬 The microbiome is medicine's next frontier!

From Fecal Transplants 💩 to probiotics 🦠, diagnostics 🔍 to designer bugs 🧪—we're decoding disease, predicting treatment, and redefining care.

But challenges remain.

🎙️ Dive into the FAQs with Got Knowledge Doc! #Microbiome #GutHealth #MedTwitter 🚀

📢 New from the SOUL trial!

💊 Oral semaglutide cuts heart attack risk in T2DM 🫀 but shows no benefit for stroke 🧠 or kidney disease 🧫.

A win for adherence, a push for CKM integration! 🔄💡 #Diabetes #Cardiology #NEJM #CKM #GLP1RA @doximity

🏌️‍♂️⛳ Living near golf courses may increase Parkinson's risk!

📊 Case-control study: Risk highest within 1–3 miles

💧 Contaminated groundwater & pesticides likely culprits

🧠 aOR up to 2.98 for 6 miles!

📉 Risk ↓ 13% per mile after 3 miles

🔗 [JAMA 2025] #Neurology #Parkinsons #EnvironmentalHealth #GolfRisk @doximity

🚨 BREAKING: Sotatercept cuts risk by 76% in advanced #PAH!

💉 Targets activin signaling

🫁 Fewer deaths, transplants & hospitalizations

📉 HR 0.24 | Trial stopped early for efficacy

⚠️ Epistaxis, ↑Hgb, telangiectasia noted

🔬 A new era in pulmonary hypertension care! #ZENITHTrial #CardioTwitter 🫀📊 @doximity

🚨New COPD diagnosis alert!🫁

A multidimensional schema using CT 🖼️ + symptoms 😮‍💨 + spirometry 📉 identified high-risk patients missed by GOLD!

📈↑Mortality (HR 1.98)

📉FEV1 decline (–7.7 mL/y)

📊 Reclassified 15% w/o obstruction as COPD!

👉CT matters. #PulmTwitter #COPD #MedTwitter @doximity

🚨 New data! In the KARDIA-2 trial, 🧬 zilebesiran—an RNAi therapeutic—cut SBP by up to 12 mmHg when added to common antihypertensives

💊. One shot, 6 months of BP control!

📉 Promising for poor adherence.

Mild AEs. #Hypertension #Cardiology #RNAi 🌍【JAMA 2025】

🧬 Big win for longevity!

A Nature Aging study shows that combining 💊 trametinib + rapamycin extends lifespan, reduces tumors, and tames inflammation in mice 🐭🔥

Dual geroprotectors = additive benefits without added toxicity 🛡️🕰️

Future of anti-aging? Watch this space 👀

#Aging #Longevity #Geroprotectors #Science 🧪 @doximity

🧠💉 New Lancet study (OPTIMISTmain) shows low-intensity monitoring after thrombolysis in mild strokes may be just as safe as standard care!

💤 Less sleep disruption, 🧑‍⚕️ lighter nursing load, ⚖️ similar outcomes.

Could this change global stroke care? 🌍🏥

#Stroke #Thrombolysis #OPTIMISTmain #Neurology