Cutting cysteine = 🔥 30% weight loss in 7 days!

🧬 Triggers stress pathways (ISR/OSR)

❌ CoA & glutathione drop

🔥 Browning fat, futile cycling, energy drain

💡 Reversible & promising for obesity research!

#Metabolism #Obesity #AminoAcids #Science 🧪⚖️🧠

🚨 TAVI Trials Update!

🆚 COMPARE-TAVI 1: 🇮🇳Myval = 💪SAPIEN 3 in safety & efficacy

🆚 ACURATE IDE: ACURATE neo2 ❌not non-inferior to 💥SAPIEN/EVOLUT

📊 Valve wars intensify! #TAVI #HeartValve #Cardiology 🫀

🌶️ Not all chili heat is created equal!

Scientists found hidden compounds—like capsianoside I & roseoside—that cool the burn without changing flavor 🔬❄️

Your next spicy dish might be hot… but not hurt.

#FlavorScience #Capsaicin #TRPV1 #FoodTech 🍽️🧠🔥

📊 New study shows Topological Flow Data Analysis (TFDA) 🌀 detects early cardiac dysfunction in childhood cancer survivors—before LVEF or strain drop!

🔍 A game-changer in cardio-onc surveillance. #CardioOncology #TFDA #EchoRevolution

📉 Mucus plugs matter! In COPD, persistent or new plugs accelerate FEV₁ decline 🫁💨

🖥️ CT imaging tracks their impact

🚬 Smoking worsens the hit

👉 Clear the plugs, preserve the lungs!

#COPD #LungHealth #NEJM #FEV1 #Pulmonology

🩺 New hope for #ResistantHypertension!

A 12-week RCT 🇰🇷 shows 💊 amiloride is noninferior to spironolactone in lowering SBP 📉

Fewer side effects, similar BP drop!

But spironolactone may still reign 👑 for organ protection 🫀🧠

🧪 #Hypertension #Cardiology #JAMA2025

🧬✨ A baby with deadly CPS1 deficiency (which results in elevated ammonia levels) gets a custom-made gene edit—delivered by lipid nanoparticles—in just 6 months! 🚀

Ammonia levels down, no hospitalizations, and hope up.

N-of-1? More like Future-of-Many. 💡👶🔬 #GeneTherapy #PrecisionMedicine #RareDisease

🚨 New framework alert!

Systemic Metabolic Disorder (SMD) gets a clinical staging makeover 🧬

From reversible risks 🌱 to systemic damage 🔥—this EAS consensus guides timely, targeted care 🎯

#MetabolicHealth #Cardiology #PrecisionMedicine #SMD 🩺📊

Pyrrho of Elis (c. 360–270 BCE) was an ancient Greek philosopher and founder of Pyrrhonism, a school of philosophical skepticism.

He advocated for epoché (suspension of judgment) as a path to ataraxia (peace of mind).

Influenced by his travels to India with Alexander the Great, Pyrrho believed that nothing could be definitively known and that by refraining from beliefs, one could achieve tranquility.

His teachings laid the foundation for later skeptical thought in philosophy and medicine.

🧬 New hope for lipid warriors!

Solbinsiran (siRNA) slashed apoB 🩸, TGs 🍟, LDL-C 💔 & liver fat 🫀 in just 205 pts with mixed dyslipidaemia.

Safe ✅ Durable ✅ Quarterly dosing? Maybe ✅

Let's talk outcomes! 🎯

#PROLONGANG3 #RNAtherapy #CardioTwitter #LipidLowering