In this episode of Note to File, Brad and Denali dig into the messy realities of modern clinical research operations:

The growing disconnect between cancer center administration and clinical operations How siloed academic structures make research less efficient (and more frustrating) Sponsors asking for constant E‑source access and screenshots (!?) The coming wave of continuous data streams (EHR, eSource, ePRO, wearables) and what that means for site workload Why the complexity of clinical trials is a feature, not a bug—and why sites should be paid accordingly EPRO in the real world: who's actually watching the data, and what do patients think is happening? Budgets, holdbacks, renegotiations, and the misaligned incentives between sites, CROs, and sponsors If you work at a site, sponsor, or CRO and feel like expectations keep going up while budgets stay flat, this one's for you.

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