In the 19th century, French doctors were finally on the cusp of treating pain. It was a new horizon in the history of medicine. Sara Black says they were experimenting with all kinds of mind-altering drugs… on themselves. And: Greg Wrenn’s journey to forgiving his parents through a psychedelic rainforest tea called ayahuasca. Also: If you’ve had a cable TV subscription in the last 20 years, chances are you’ve seen at least an episode or two of Crime Scene Investigation. Tracy Sohoni looks at how CSI depicts drugs and violence over the course of its 15 seasons.

Later in the show: Sabrina Laroussi studies books about the world of Latin American drug trafficking called narconovelas. She says this emerging genre of literature tends to glorify drug lords and downplay the brutality of drug war violence. Plus: Whether through a family member, friend, or even our own personal struggles - we’ve all been touched by addiction. But Regina Brisgone says addiction isn’t a one-size-fits-all disease, women experience it differently than men.