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Caring for patients with severe traumatic brain injury (TBI)—especially pediatric patients—is high-stakes and high-stress. In severe TBI, primary brain injury occurs at the moment of impact; our primary goal in the emergency department is preventing secondary brain injury caused by hypoxia, hypoperfusion, elevated intracranial pressure (ICP), seizures, hyperthermia, and dysglycemia.
In this episode, ED Clinical Pharmacist Haley Burhans returns to walk us through key medications for the acute management of severe TBI. We’ll cover airway management, rapid sequence intubation (RSI) drug choices, hyperosmolar therapy, seizure prophylaxis, TXA, and post-resuscitation care.
1. Airway & Rapid Sequence Intubation (RSI)
Optimizing oxygenation and ventilation is critical, as hypoxemia directly contributes to secondary brain injury. Selecting hemodynamically neutral agents is essential to maintain cerebral perfusion pressure (CPP).
Induction Agents
Paralytics
Pre-Medications (Lidocaine vs. Fentanyl)
2. Post-Intubation Sedation & Hemodynamic Support
3. Seizure Prophylaxis
Post-traumatic seizures increase metabolic demand and elevate ICP.
4. Hyperosmolar Therapy for Cerebral Edema
When signs of impending herniation or acute ICP elevation are present:
5. Role of Tranexamic Acid (TXA)
6. Critical ED Targets & Common Pitfalls
What are your go-to meds for severe TBI? What do you avoid? Share your experience with us on social media @empulsepodcast or at ucdavisem.com
Hosts:
Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis
Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis
Guests:
Haley Burhans, PharmD, Emergency Medicine Clinical Pharmacist at UC Davis
Resources:
ACEP Critical Care Medicine: Key Aspects in the Management of TBI in the ED to Minimize Secondary Injury by Miyant’e Newton, MD, March 12, 2024
Brain Trauma Foundation Guidelines for the Management of Severe TBI, 4th Edition
Brain Trauma Foundation Guidelines for the Management of Pediatric Severe TBI, 3rd Edition
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Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
Ultrasound-guided nerve blocks are no longer just a niche skill for fellowship-trained ultrasound specialists—they are a core component of modern multimodal pain management in the ED. Endorsed by ACEP, nerve blocks can offer rapid, targeted pain relief without relying solely on systemic opioids, making everything from rest to imaging and procedural workups significantly more comfortable for patients.
Today, Dr. Carlos Mikell, UC Davis Emergency Ultrasound Faculty and nerve block expert, joins us to share why every emergency physician should adopt nerve blocks as part of their practice. We’ll break down the top ED blocks, explore innovative indications like genicular nerve blocks for knee pain, and discuss essential safety protocols and how to get started – or become more comfortable – with blocks in your ED.
Why Nerve Blocks Belongs in the ED
The Most Common ED Nerve Blocks
According to data from the National Ultrasound Guided Nerve Block Registry:
Innovative Block Spotlight: Genicular Nerve Block
Streamlining Nerve Blocks in Your Department
To move nerve blocks from a rare procedure to a routine clinical tool:
Non-Negotiable Safety Guidelines & LAST Prevention
Nerve blocks are generally low-risk, but vigilance is critical to avoid complications like Local Anesthetic Systemic Toxicity (LAST) or direct nerve injury:
What is your favorite ultrasound-guided nerve block? What barriers do you encounter to doing blocks in the ED? We’d love to hear form you! Connect with us on social media @empulsepodcast or connect with us on ucdavisem.com
Hosts:
Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis
Dr. Sarah Medeiros, Professor of Pediatric Emergency Medicine at UC Davis
Guest:
Dr. Carlos Mikell, Assistant Professor of Emergency Medicine and Ultrasound Faculty at UC Davis
Resources:
ACEP Policy Satement: Ultrasound Guidelines: Emergency, Point-of-care, and Clinical Ultrasound Guidelines in Medicine, June 2016
ACEP Now: How To Build an Ultrasound-Guided Nerve Block Program
By Arun Nagdev, MD; Kaitlen Howell, MD; Akash Desai, MD; David Martin, MD; and Daniel Mantuani, MD, MPH | on January 6, 2023
ACEP Sonoguide: Nerve Blocks
NURVE Block Registry
Brown J, Milgrim F, Driver L, et al. Efficacy and Safety of Adjunct Medications in ED Ultrasound-Guided Nerve Blocks: A National Ultrasound-Guided NeRVE (NURVE) Block Registry Study. Acad Emerg Med. 2025 Dec;32(12):1299-1308. doi: 10.1111/acem.70128. Epub 2025 Aug 27. PMID: 40873157.
Goldsmith A, Driver L, Duggan NM, et al. Complication Rates After Ultrasonography-Guided Nerve Blocks Performed in the Emergency Department. JAMA Netw Open. 2024 Nov 4;7(11):e2444742. doi: 10.1001/jamanetworkopen.2024.44742. Erratum in: JAMA Netw Open. 2024 Dec 2;7(12):e2455847. doi: 10.1001/jamanetworkopen.2024.55847. PMID: 39535792; PMCID: PMC11561692.
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Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
Disclaimer: The opinions expressed on this podcast are those of the hosts or guests and do not necessarily reflect the views of UC Davis Department of Emergency Medicine, UC Davis Health, or their parent organizations.
The Outbreak
With over 17,000 cases reported across the U.S., a massive Cyclospora outbreak has taken center stage in public health news, marking it as the third-largest foodborne outbreak in modern American history (behind the 1994 Schwan’s ice cream salmonella outbreak and the 1985 Illinois milk outbreak). Infection causes gastrointestinal symptoms, including diarrhea, bloating, nausea and sometimes vomiting.
So, what’s actually driving this surge? Is it safe to eat salad? Pediatric infectious disease expert Dr. Dean Blumberg joins us to break down the science behind the “explosive” symptoms, separate real outbreak epicenters from everyday travel cases, and when to test and treat.
Transmission & Geography
Pathophysiology & Presentation
Diagnostic Strategy
Routine “O&P x3” tests are obsolete—use multiplex PCR panels (e.g., GI BioFire).
Treatment
Have you seen many Cyclospora cases? Or an influx of concerned patients with mild GI symptoms? Share your experience with us on social media @empulsepodcast or at ucdavisem.com
Hosts:
Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis
Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis
Guests:
Dr. Dean Blumberg, Chief of Pediatric Infectious Diseases at UC Davis
Resources:
CDC: Cyclosporiasis
AAP News: CDC offers guidance on cyclosporiasis outbreaks for clinicians, public July 14, 2026 Melissa Jenco, Senior News Editor
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Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
Cannabinoid Hyperemesis Syndrome (CHS) continues to be a major clinical challenge in the emergency department. Patients present with severe abdominal pain, intractable vomiting, and significant fluid and electrolyte derangements. CHS often affects people who have been using cannabis routinely for months to years – it can be difficult for patients to understand that their symptoms are related to cannabis.
Today, emergency pharmacist Haley Burhans joins us to discuss first-line treatments, fluid management, discharge strategies, and how to navigate these tough bedside conversations.
First-Line Therapies: Haldol vs. Droperidol
Backup Options & Anti-Emetics
QTc Prolongation Warning:
Chronic vomiting leads to electrolyte depletion. Combining anti-emetics and haloperidol or droperidol increases the risk of QTc prolongation.
Baseline EKG: Not strictly required for every low-risk patient, but strongly recommended for patients with multiple risk factors (e.g., co-ingestion/use of methadone, history of heart failure, or severe baseline bradycardia).
Fluid Resuscitation & Electrolyte Management
CHS patients can vomit to the point of severe dehydration and profound electrolyte/acid-base derangements.
Discharge Planning: What to Send Home
Navigating the Bedside Conversation
Explaining to a chronic user that their daily cannabis—the very thing they use to relieve nausea—is causing their illness requires empathy and validation.
What do you find most helpful for treating CHS? How do you have these difficult conversaions with your patients? Share your experience with us on social media @empulsepodcast or at ucdavisem.com
Hosts:
Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis
Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis
Guests:
Haley Burhans, PharmD, Emergency Medicine Clinical Pharmacist at UC Davis
Resources:
Borgundvaag B, Bellolio F, Miles I, et al. Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department. Acad Emerg Med. 2024 May;31(5):425-455. doi: 10.1111/acem.14911. PMID: 38747203.
Rech MA, Shalaby M, Gage KA, Gottlieb M. Managing Cannabinoid Hyperemesis Syndrome. Ann Emerg Med. 2026 Jun;87(6):717-722. doi: 10.1016/j.annemergmed.2025.12.024. Epub 2026 Feb 3. PMID: 41632059.
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Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
A landmark international trial published in the New England Journal of Medicine evaluated whether fluid type impacts patient outcomes.
In this episode, we welcome back guest host Dr. Neelou Weeker and ED nurse Leigh Clary to talk about a tough emergency medicine reality that we often avoid discussing: what teamwork looks like when, despite our best efforts, the patient doesn’t survive. We work though a recent, emotionally heavy resuscitation and explore how TeamSTEPPS tools—specifically the structured debrief—serve as a vital safety net for our own mental health, helping us find our footing and reclaim our humanity in a chaotic environment.
The Reality of “Doing Everything Right” and Still Losing
We often connect good teamwork with saving lives, but in the ED, bad outcomes sometimes happen. The true test of a team’s culture is how we handle the aftermath of those tough cases.
1. The Emotional Roller Coaster of the ED
2. The Anatomy of a High-Quality Debrief
Debriefing after a tough case should be a priority, not a luxury. A solid debrief balances a clinical review with immediate psychological first aid.
The Power of Prioritization: The emergency department is chronically busy, but a culture of safety means charge nurses actively shuffle staff and adjust coverage to carve out the 10 to 15 minutes required for a team to debrief.
Applying TeamSTEPPS to Team Longevity
1. The Need for a Clinical Respite
Data shows that the most important thing for a clinician after a bad outcome is just a brief break from the clinical area to regroup and compose themselves. Since we physically can’t just leave the ED to get a breath of fresh air, a structured debrief acts as that necessary “bubble” outside of active patient care.
2. Modeling Vulnerability as Leaders
To move away from the expectation that healthcare workers must act as emotionless automatons, leaders must intentionally model healthy processing.
Key Takeaways
Do you use TeamSTEPPS or a similar model in your ED? We’d love to hear what has been successful for your team. Hit us up on social media @empulsepodcast or connect with us on ucdavisem.com
Host:
Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis
Guest Host:
Dr. Neelou Tabatabai, Assistant Professor of Emergency Medicine at UC Davis
Guest:
Leigh Clary, RN, BSN, RN, CEN, ADCES, MICN , ED Nurse and TeamSTEPPS Project Lead at UC Davis
Resources:
TeamSTEPPS Player of the Month Program, Presentation by Leigh Clary and Jose Metica
TeamSTEPPS™: Team Strategies and Tools to Enhance Performance and Patient Safety Heidi B. King, MS, CHE, James Battles, PhD, David P. Baker, PhD, Alexander Alonso, PhD, Eduardo Salas, PhD, John Webster, MD, MBA, Lauren Toomey, RN, BSBA, MIS, and Mary Salisbury, RN, MSN.
TeamSTEPPS Pocket Guide – Agency for Healthcare Research and Quality
EM Pulse: TeamSTEPPS, September 17, 2021
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Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
Disclaimer: The opinions expressed on this podcast are those of the hosts or guests and do not necessarily reflect the views of UC Davis Department of Emergency Medicine, UC Davis Health, or their parent organizations.
In this episode, the we welcome back guest host, Dr. Neelou Weeker, and ED nurse, Leigh Clary, to discuss the critical intersection of language barriers, patient equity, and emergency care. Through two powerful clinical scenarios, the team explores the “gold standards” of medical translation, the challenges of resource-limited community settings, and how TeamSTEPPS tools—specifically closed-loop communication and situational monitoring—can be leveraged to ensure true informed consent and patient safety.
The Gold Standard vs. Clinical Reality
Providing equitable care means ensuring every patient, regardless of language or culture, fully understands their medical team. While academic centers are often highly resourced, executing communication seamlessly remains a universal challenge.
1. Translation Tools and Hierarchy
2. Academic vs. Community and Rural Settings
Applying TeamSTEPPS to Patient Communication
We routinely use TeamSTEPPS tools to communicate with our fellow clinicians, but we must remember that the patient is the most important member of the healthcare team.
1. Closed-Loop Communication & The Teach-Back Method
To confirm true patient understanding, avoid simple “yes or no” questions, nods, or smiles. Instead, utilize the Teach-Back Method, requiring the patient to repeat the instructions or choices back to you in their own words.
2. Situational Monitoring
Resuscitative environments are chaotic, and the primary physician trying to run a cod or secure an airway has immense cognitive load.
Reconciling Clinical Urgency with Informed Consent
How do you balance the immediate need to save a life with the time-consuming process of formal translation?
Key Takeaways
Do you use TeamSTEPPS or a similar model in your ED? We’d love to hear what has been successful for your team. Hit us up on social media @empulsepodcast or connect with us on ucdavisem.com
Host:
Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis
Guest Host:
Dr. Neelou Tabatabai, Assistant Professor of Emergency Medicine at UC Davis
Guest:
Leigh Clary, RN, BSN, RN, CEN, ADCES, MICN , ED Nurse and TeamSTEPPS Project Lead at UC Davis
Resources:
TeamSTEPPS Player of the Month Program, Presentation by Leigh Clary and Jose Metica
TeamSTEPPS™: Team Strategies and Tools to Enhance Performance and Patient Safety Heidi B. King, MS, CHE, James Battles, PhD, David P. Baker, PhD, Alexander Alonso, PhD, Eduardo Salas, PhD, John Webster, MD, MBA, Lauren Toomey, RN, BSBA, MIS, and Mary Salisbury, RN, MSN.
TeamSTEPPS Pocket Guide – Agency for Healthcare Research and Quality
EM Pulse: TeamSTEPPS, September 17, 2021
***
Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
Disclaimer: The opinions expressed on this podcast are those of the hosts or guests and do not necessarily reflect the views of UC Davis Department of Emergency Medicine, UC Davis Health, or their parent organizations.
It is getting hot in California, which has us thinking about the massive carbon footprint of healthcare. The emergency department is famously resource-heavy, but can we save lives and reduce waste? Dr. David Barnes joins us to explain how going green isn’t just about being a “tree hugger”—it’s about saving money, cutting waste, and making our hospitals resilient against supply chain chaos.
Defining Healthcare Sustainability
The Three Scopes of Emissions
Clinical Traps: Where We Waste the Most
Shifting the Culture
Key Takeaways for the ED Clinician
Hosts:
Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis
Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis
Guest:
Dr. David Barnes, Professor of Emergency Medicine, Director of ED Sustainability, and Member of the Sustainability Committee at UC Davis Health
Resources:
Practice Greenhealth
Health Care Without Harm
Green ED (Royal College of Emergency Medicine)
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Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
It’s one of the most common—and most frustrating—complaints in the Emergency Department: the patient covered head-to-toe in hives, miserable, itching, and desperate for relief. In this episode of EM Pulse, we welcome back ED Clinical Pharmacist Haley Burhans to tackle the “uncomfortable” topic of urticaria. We move past the myths of one-and-done doses and explore why your standard allergy dosing might be leaving your patients itching for more.
The Power of Second-Generation Antihistamines
Haley explains why second-generation antihistamines (cetirizine, levocetirizine, fexofenadine) should be your first-line ED therapy, rather than the old school standard, diphenhydramine (Benadryl).
The Steroid Trap and the Rebound Effect
Patients often come in requesting steroids but they are NOT the primary cure for urticaria.
Beyond the Basics: Benadryl and the MABs
Key Takeaways
How do you handle the “itch that won’t quit”? Do you have a favorite antihistamine cocktail? Share your experience with us on social media @empulsepodcast or at ucdavisem.com
Hosts:
Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis
Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis
Guests:
Haley Burhans, PharmD, Emergency Medicine Clinical Pharmacist at UC Davis
Resources:
The international EAACI/ GA²LEN/ EuroGuiDerm/ APAAACI guideline for the definition, classification, diagnosis, and management of urticaria
Emergency Department and Primary Care Clinical Pathway for Evaluation/Treatment of Children with Urticaria or Angioedema (CHOP)
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Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
Menopause is not just “hot flashes”—it is a systemic hormonal shift that affects almost every organ system. For the emergency clinician, recognizing the symptoms of perimenopause and menopause is crucial for expanding the differential diagnosis once life-threatening conditions are ruled out. Dr. Pam Dyne joins us for a crash course on evaluating menopausal and perimenopausal patients in the ED.
The “Why”: Why Menopause Matters in the ED
Physiology Refresher: When the Ovaries Retire
Hormone Therapy (MHT): Debunking the Myths
A major barrier to treatment is the “mass hysteria” caused by the 2002 Women’s Health Initiative (WHI) study.
The Difficult Pelvic Exam: ED “Hacks”
Examining older female patients can be challenging for myriad reasons, including physical limitations and lack of proper ED pelvic exam gurneys.
Clinical Pearls: Specific Presentations
1. Post-Menopausal Bleeding
2. Genitourinary Syndrome of Menopause (GSM)
3. Pelvic Organ Prolapse
4. Musculoskeletal (MSK) Syndrome of Menopause
Key Takeaways for the ED Clinician
Hosts:
Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis
Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis
Guest:
Dr. Pamela Dyne, Professor of Clinical Emergency Medicine and Chief Physician Wellness Officer at Olive View UCLA Medical Center
Resources:
North Americal Menopause Society (NAMS) – Menopause.org
UTIs and Estrogen: the Overlooked Link, By Ashley Winter, MD; Rachel Rubin, MD; and Howie Mell, MD, MPH. ACEP Now, February 16, 2022
American College of Obstetricians and Gynecologists (ACOG): Menopause
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Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
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