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Editor-in-Chief, Robert Amdur, MD, discusses using molecular markers to make decisions about adjuvant radiotherapy for Endometrial Cancer. The main references for the podcast are the PROshot article in the January 2024 issue of PRO (2024, Issue 1, January/February) and a Topic Discussion paper currently published online ahead of print with title "Path to Precision: Refining Radiation Therapy Guidelines for Early-Stage Endometrial Cancer Through Incorporation of Primary Tumor Size, Lower Uterine Segment Invasion, and Molecular Markers" (PMID 38048989).