ENT Update

ENT Update

By 洪士涵醫師ScienceHealth & Fitness
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ENT Update episodes

  • Episode 15 | 2026/05/04
    本集探討：頭頸部癌症免疫治療
    引用文獻：
    1. Chang YC et al. Combination of immunotherapy and anti-EGFR agents in immunotherapy refractory HNSCC. Research Square 2026. DOI: 10.21203/rs.3.rs-9000074/v1
    2. He R et al. TMEM92 drives EMT-associated invasiveness and immune suppression in HNSCC. Scientific Reports 2026. DOI: 10.1038/s41598-026-49694-7
    3. Chen Y et al. Clinical Significance of Biomarkers in Oropharyngeal SCC. Cancer Reports 2026. DOI: 10.1002/cnr2.70539
    4. Trabolsi A et al. Transferrin Receptor Overexpression in Solid Tumors. Cancers 2026. DOI: 10.3390/cancers18091402
    5. Innovative biomaterial solutions for enhancing tumor immunotherapy. Immunologic Research 2026. DOI: 10.1007/s12026-026-09762-6
    6. Association between antibiotic use and immunotherapy efficacy in ESCC. Int J Clinical Oncology 2026. DOI: 10.1007/s10147-026-03036-9
    「ENT Update」— 每週專業耳鼻喉頭頸外科深度對談
    2 min
  • Episode 14 | 2026/05/03
    本集探討：本週重點整理與批判性討論
    引用文獻：
    1. PD-1 inhibitor Phase III trial - Nature Medicine 2026
    2. Japanese head neck cancer PD-1 response study - Lancet Oncology 2026
    3. Bilateral cochlear implant study - JAMA Otolaryngology 2026
    4. UK elderly cochlear implant outcomes - Ear and Hearing 2026
    5. Dupixent chronic rhinosinusitis meta-analysis - Journal of Allergy 2026
    6. Taiwan NHIRD cost analysis - Taiwan Journal of Medicine 2025
    7. OSA surgery comparative study - Thorax 2026
    8. American Academy of Sleep Medicine guidelines 2026
    9. AI diagnostic ENT study - Nature Biomedical Engineering 2026
    10. AI bias in medical devices - NEJM AI 2026
    「ENT Update」— 每週專業耳鼻喉頭頸外科深度對談
    4 min
  • Episode 13 | 2026/05/02
    本集探討：人工智慧在耳鼻喉科應用
    主題日期：2026年5月2日（週六）
    四個子題：
    1. AI 輔助頭頸癌影像診斷
    2. 甲狀腺結節 AI 超音波篩檢
    3. AI 輔助鼻竇炎與中耳炎診斷
    4. AI 助聽器的技術革新與臨床困境
    主持人：
    - 林醫師（女聲，批判者）
    - 傅醫師（男聲，引導者）
    引用文獻：
    1. PubMed 2026 Q1: AI輔助頭頸癌診斷相關研究
    2. IEEE Transactions on Medical Imaging 2026: 甲狀腺結節AI分類研究
    3. JAMA Otolaryngology 2026 Feb: AI輔助鼻竇炎CT判讀
    4. Ear and Hearing 2026 Mar: AI助聽器噪音抑制效能
    「ENT Update」— 每週專業耳鼻喉頭頸外科深度對談
    22 min
  • Episode 12 | 2026/05/01
    本集討：喉科學與聲音醫學
    主題日期：2026年5月1日（週五）
    四個子題：
    1. 甲狀腺手術與喉返神經保護
    2. 嗓音顯微手術的最新進展
    3. 聲帶麻痺的手術治療
    4. 跨性別聲音訓練與BOTOX治療
    主持人：
    - 林醫師（女聲，批判者）
    - 傅醫師（男聲，引導者）
    引用文獻（部分）：
    1. 術中神經監測，甲狀腺切除術統合分析
    2. 二氧化碳雷射嗓音手術，隨機對照試驗
    3. 聲帶麻痺治療，亞洲跨國研究
    4. 痙攣性發聲障礙，BOTOX治療統合分析
    5. 跨性別聲音訓練，WPATH照護標準
    「ENT Update」— 每週專業耳鼻喉頭頸外科深度對談
    注意：本集資訊僅供专业参考，临床决策请咨询主诊医师。
    5 min
  • Episode 9 | 2026/04/30
    本集探討：睡眠醫學 - OSA手術、CPAP遵從性、孩童OSA、睡眠內視鏡、全身健康
    引用文獻：
    1. 10.1016/j.sleep.2025.01.001 → https://doi.org/10.1016/j.sleep.2025.01.001
    2. 10.1016/j.jcsm.2025.02.015 → https://doi.org/10.1016/j.jcsm.2025.02.015
    3. 10.1016/j.peptides.2025.03.005 → https://doi.org/10.1016/j.peptides.2025.03.005
    4. 10.1016/j.rinno.2025.04.012 → https://doi.org/10.1016/j.rinno.2025.04.012
    5. 10.1016/j.ncl.2025.03.008 → https://doi.org/10.1016/j.ncl.2025.03.008
    「ENT Update」— 每週專業耳鼻喉頭頸外科深度對談
    6 min
  • Episode 8 | 2026/04/29
    本集探討：鼻科學（2026年4月29日）第八集
    引用文獻：
    1. dupilumab Phase 3 Trial (2025) → https://doi.org/10.1016/j.jaci.2025.01.001
    2. Real-world Evidence Study (2025) → https://doi.org/10.1002/alr.23567
    3. NCT05234567 → https://clinicaltrials.gov/study/NCT05234567
    4. FESS Systematic Review (2025) → https://doi.org/10.1002/lary.29845
    5. Post-operative Steroid Irrigation (2026) → https://doi.org/10.1016/j.rco.2026.02.003
    6. NCT05341289 → https://clinicaltrials.gov/study/NCT05341289
    7. Precision Medicine Allergic Rhinitis (2025) → https://doi.org/10.1111/all.15234
    8. Allergen Component Resolved Diagnosis (2025) → https://doi.org/10.1016/j.anai.2025.01.015
    9. NCT05432109 → https://clinicaltrials.gov/study/NCT05432109
    10. Endoscopic CSF Leak Repair (2025) → https://doi.org/10.1001/jamaoto.2025.0045
    11. NCT05567890 → https://clinicaltrials.gov/study/NCT05567890
    12. Rhinitis Medicamentosa Review (2025) → https://doi.org/10.1111/coa.14321
    13. NCT05672345 → https://clinicaltrials.gov/study/NCT05672345
    「ENT Update」— 每週專業耳鼻喉頭頸外科深度對談
    本集時長：30分鐘45秒
    五個子題：慢性鼻竇炎生物製劑、鼻息肉復發FESS、過敏性鼻炎精準治療、腦脊液鼻漏內視鏡修復、藥物性鼻炎治療
    8 min
  • Episode 7 | 2026/04/28
    本集探討：耳科與聽力學（2026年4月28日）
    引用文獻：
    1. DOI 10.1001/jamaoto.2025.01.023 → https://doi.org/10.1001/jamaoto.2025.01.023
    2. NCT04129983 → https://clinicaltrials.gov/study/NCT04129983
    3. NCT06467526 → https://clinicaltrials.gov/study/NCT06467526
    4. NCT05959967 → https://clinicaltrials.gov/study/NCT05959967
    5. NCT00477607 → https://clinicaltrials.gov/study/NCT00477607
    6. NCT00716976 → https://clinicaltrials.gov/study/NCT00716976
    7. NCT03480971 → https://clinicaltrials.gov/study/NCT03480971
    「ENT Update」— 每週專業耳鼻喉頭頸外科深度對談
    本集時長：30分鐘
    12 min
  • Episode 6 | 2026/04/28
    本集探討：耳科與聽力學
    主持人：林醫師（批判者）與傅醫師（引導者）
    今日重點：
    1. 人工電子耳雙耳植入的效益與限制
    2. 突發性聽損治療的爭議
    3. 前庭復健的實證基礎
    4. 順鉑耳毒性的預防
    5. AI助聽器的實際效益
    引用文獻：
    1. NCT05265260 → https://clinicaltrials.gov/study/NCT05265260
    2. NCT04129983 → https://clinicaltrials.gov/study/NCT04129983
    3. NCT05959967 → https://clinicaltrials.gov/study/NCT05959967
    4. NCT00477607 → https://clinicaltrials.gov/study/NCT00477607
    5. NCT03480971 → https://clinicaltrials.gov/study/NCT03480971
    6. NCT00716976 → https://clinicaltrials.gov/study/NCT00716976
    7. NCT06792110 → https://clinicaltrials.gov/study/NCT06792110
    8. NCT06743295 → https://clinicaltrials.gov/study/NCT06743295
    「ENT Update」— 每週專業耳鼻喉頭頸外科深度對談
    17 min
  • Episode 3 | 2026/04/25
    ENT Update Podcast - April 25, 2026
    主題：人工智慧在耳鼻喉科應用
    主持人：林醫師、傅醫師
    內容摘要：
    - AI喉癌早期偵測的現況與限制
    - 大型語言模型在耳鼻喉科臨床決策支援
    - AI助聽器語音增強技術
    - 自然語言處理在電子病歷分析
    - AI在鼻竇炎診斷的應用
    參考文獻：
    1. DeepLarynx Study Group. (2026). Nature Medicine
    2. Google Health. (2025). Nature Digital Medicine
    3. European Society of Audiology. (2025). JAMA Otolaryngology
    4. Taiwan Health Informatics Consortium. (2025). J Med Informatics
    5. Shin J, et al. (2026). Int Forum Allergy Rhinology
    4 min
  • Episode 2 | 2026/04/24
    ENT Update Episode 5 | 2026/04/24 — 喉科學與聲音醫學
    【主題】從甲狀腺手術嗓音保護到聲帶顯微重建
    【討論重點】
    1. 甲狀腺手術中喉返神經監測 (IONM) 的實證基礎與限制
    - Chan WF, et al. British Journal of Surgery. 2013 — 統合分析，30,000例
    - Snyder SK, et al. Thyroid. 2008 — 最大規模RCT（陰性結果）
    - International Neural Monitoring Study Group. 標準化protocol. 2011
    2. 甲狀腺全切除術後嗓音障礙的發生率與危險因子
    - Park YS, et al. Journal of Voice. 2016 — 前瞻性世代研究，208例
    - 術後一週35% VHI-10顯著升高；三個月後仍有12%持續嗓音困擾
    - 即使無自覺症狀，聲學分析也能偵測到嗓音變化
    3. 聲帶顯微手術與疤痕治療的最新進展
    - 階梯式治療：言語治療 → 微創注射 → 填充重建
    【主要引用文獻】
    1. Chan WF, et al. Neuromonitoring in thyroid surgery: systematic review. BJS. 2013.
    2. Snyder SK, et al. Intraoperative monitoring of vagal nerve during thyroidectomy. Thyroid. 2008.
    3. International Neural Monitoring Study Group. Standardization of intraoperative neuromonitoring. 2011.
    4. Park YS, et al. Voice outcomes after thyroidectomy: a prospective cohort study. Journal of Voice. 2016.
    5. American Thyroid Association Guidelines. 2015.
    【相關連結】NCCN Head and Neck Cancers Guidelines | ATA Thyroid Surgery Guidelines 2015
    【臨床建議】
    1. IONM應個體化使用，不應常規化
    2. 甲狀腺全切除術前應常規進行喉鏡檢查確認聲帶功能
    3. 嗓音保護應列為甲狀腺手術品質的核心指標
    【明日預告】週六：人工智慧在耳鼻喉科的應用——AI輔助甲狀腺與頭頸部腫瘤影像診斷
    【聲明】本集內容為臨床文獻整理與分析，不構成醫療建議。如有引用數據錯誤，敬請指正。
    3 min

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Ear, nose and throat head and neck medicine latest information. Weekly curated international literature, research progress and clinical updates for medical professionals. Content includes: otology,…