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Summary 3.11 Macrolides - Nursing Pharmacology 

Chapter 3.11 discusses macrolides, a broad-spectrum antibiotic class that inhibits bacterial RNA protein synthesis, making them bacteriostatic. They're effective against gram-positive and some gram-negative bacteria, treating respiratory, skin, and sexually transmitted infections. Side effects include GI upset, photosensitivity, and potential QT interval prolongation. Liver function should be monitored, and patients should avoid excessive sunlight.

Multiple Choice Questions

1. How do macrolides work? a) Inhibit protein synthesis b) Disrupt cell wall synthesis c) Inhibit RNA protein synthesis d) Prevent DNA replication
2. Which condition can macrolides treat? a) Diabetes b) Hypertension c) Respiratory infections d) Fractures
3. What side effect is common with macrolides? a) Weight gain b) GI upset c) Hair loss d) Increased appetite
4. Macrolides should be used cautiously in patients with: a) Liver disease b) Allergies c) Asthma d) High blood pressure
5. Patients taking macrolides should: a) Take antacids b) Avoid sunlight c) Eat more salt d) Increase sugar intake

Answer Key

1. c) Inhibit RNA protein synthesis
2. c) Respiratory infections
3. b) GI upset
4. a) Liver disease
5. b) Avoid sunlight