Curing with Sound

Ep-23: Treating Melanoma with Focused Ultrasound and Immunotherapy: A Conversation with Lynn Dengel, MD

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In this episode of Curing with Sound, Lynn Dengel, MD, a surgical oncologist at UVA Health, discusses her groundbreaking clinical trial combining focused ultrasound with immunotherapy to treat patients with advanced melanoma.  She shares insights into how this Foundation-funded trial – which is still enrolling patients – could help those who don't benefit from standard immunotherapy alone.

Key points from the conversation:

  • Melanoma is the most invasive type of skin cancer and accounts for the majority of skin cancer deaths. More than 100,000 Americans are diagnosed with melanoma each year.

  • The study will enroll approximately 11 participants with advanced melanoma who are receiving a cancer immunotherapy drug (PD-1 antibody blockade) as part of their regular care and having the melanoma surgically removed.

  • Dr. Dengel explains how focused ultrasound not only targets tumor tissue but may also create an enhanced environment for immunotherapy to work more effectively.

  • As a senior advisor to the Foundation's immunotherapy program, Dr. Dengel highlights the value of cross-institutional collaboration in advancing focused ultrasound research and improving patient outcomes.

    • UVA Health Study: Seeking Adult Patients with Advanced Melanoma Who are Receiving Immune Therapy and Who are Planning to Receive Surgery - MORE INFO

    EPISODE TRANSCRIPT


    ----------------------------

    QUESTIONS?
    Email [email protected] if you have a question or comment about the show, or if you would you like to connect about future guest appearances. 

    Email [email protected] if you have questions about focused ultrasound or the Foundation. 

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